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Doctor insights on: Ana Tests

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What does it mean when you have symptoms and have had several positive and both negative ANA tests and autoimmune tests? I want answers to my sympt.

What does it mean when you have symptoms and have had several positive and both negative ANA tests and autoimmune tests? I want answers to my sympt.

Not enough info: You have not provided enough specifics about you symptoms to draw a conclusion. Have you seen a rheumatologist? ...Read more

Ana (Definition)

An "ana" is a blood test used to screen a person for the possibility of several autoimmune diseases. It is important to remember that this is a screening test and a positive result only indicates more testing may be warranted. No blood test is perfect, and getting to a diagnosis is usually much more complex than drawing blood and looking at a number ...Read more


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Could a person with 2 different negative ANA tests have lupus?

Could a person with 2 different negative ANA tests have lupus?

Yes, but ANA: Negative lupus is uncommon. ANA is one of the criteria for diagnosing lupus, but a negative ANA does not rule out lupus. See this site for more info.

http://www. Webmd. Com/lupus/guide/laboratory-tests-used-diagnose-evaluate-sle ...Read more

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Although I have had many symptoms and +ana tests my rheumy seems to be reluctant to diagnos lupus. Says autoimmune yes but no specific dx. Is this norm?

Although I have had many symptoms and +ana tests my rheumy seems to be reluctant to diagnos lupus. Says autoimmune yes but no specific dx. Is this norm?

Yes: Nobody really knows what lupus is and it's diagnosed by criteria -- get a certain number and you can make the call. The real question is, "do we want to treat this? If so, how? " I believe in "semi-lupus", an entity often ana-positive and with some other lupus signs but never quite sufficient to make the call -- it tends to remit. Stay proactive & get a 2nd opinion as you think best. ...Read more

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I have had 2 positive ANA tests & 1 negative. I was just dx'd with small fiber axonopathy. I have pots/dysautonomia. What r the chances it's autoimmun?

Possible: There are a number of causes for small fibre neuropathy, and if associated with lupus, would of course be autoimmune, but other categories could include toxins, such as industrial solvents, alcohol and nutritional issues, and even early presentation of diabetes. Cancer at a distance, para-neoplastic syndromes may present this way rarely. Your doc will guide all of this. ...Read more

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Do I have scleroderma 46 year old female positive. Ana two times 1:40 and 1:160 negative nucleolar pattern negative subtests. No skin issues, eye irritation once in awhile. Ana tests done 1 1/2 years ago. Rheumatalogist finds nothing except ANA and I

Do I have scleroderma 46 year old female positive. Ana two times 1:40 and 1:160 negative nucleolar pattern negative subtests. No skin issues, eye irritation once in awhile. Ana tests done 1 1/2 years ago. Rheumatalogist finds nothing except ANA and I

Unlikely: The combination of your very low ANA titers and lack of symptoms make scleroderma unlikely. Patterns of ANA are not reproducible, and an ANA titer of <1:80 has been reported in up to 13% of healthy patients.
Ana is a screening assay which should be followed by a more specific autoantibody tests. 95% of scleroderma patients will have an identifiable positive autoantibody. (uptodate. Com, 7/16/12). ...Read more

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Do I have scleroderma 46 year old female positive. Ana two times 1:40 and 1:160 negative nucleolar pattern negative subtests. No skin issues, eye irritation once in awhile. Ana tests done 1 1/2 years ago. Rheumatalogist finds nothing except ANA and I

Nothing to do: The only thing you can do is to wait. In rheumatologic diseases, the components of the syndrome sometimes don't manifest at once but during the curse of several years. Worrying now for something that can be nothing is not good for your mind. Positive ANA test doesn't mean that you have a disease. ...Read more

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Sir, my ESR is 34, rf, aso, ANA tests al are -ve. I ve joint pain in finger, knee & toe. Mild swelling in 3 fingers at distal proximal joint. Pls help?

Sir, my ESR is 34, rf, aso, ANA tests al are -ve. I ve joint pain in finger, knee & toe. Mild swelling in 3 fingers at distal proximal joint. Pls help?

? Psoriatic Arthritis: Do you have a history of psoriasis? The dip inflammation may be consistent with psoriatic arthritis. Sometime the joint swelling can precede any evidence of the skin disease. See a rheumatologist if you have not done so already. ...Read more

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How are ANA blood tests related to autoimmune disease?

How are ANA blood tests related to autoimmune disease?

One marker: Anti-nuclear antibodies (ANA) are one marker of auto-immune disease. There are sub-types of ANA that have specificity for different diseases. The antibodies may not be the casue of disease, but a marker of the disorder. ...Read more

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C-ANCA, P-ANCA, ANA & CRP tests stands for what.?? Does it belongs to any cancer testing for kidneys.?? Please suggest

Vasculitis tests: The first two test for autoimmune diseases that affect your vessels. These diseases are uncommon, lethal if missed, and fairly easy to treat. ANA is a screen for some of the autoimmune illnesses, and CRP is a not-that-helpful measure of inflammation that's often misleading. These are not cancer tests. ...Read more

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36F. My c-reactive protein is 17.4. ANA/Ra tests negative. Same with all other rheumatology tests. Is this emergency? I'm panic. 5'3/180

Needs attention: It is not an emergency, but it points to an inflammatory condition that needs attention and evaluation by a doctor. ...Read more

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Unexplained high ANA, other tests norm. Lupus symptoms, but spondylitis symptoms too. Heel pain, SI pain sometimes, shoulder weak sometimes. Full MRI?

Unexplained high ANA, other tests norm. Lupus symptoms, but spondylitis symptoms too. Heel pain, SI pain sometimes, shoulder weak sometimes. Full MRI?

How about...: HLA B-27 (I know you're not the typical gender), Rheumatoid Factor, ESR, CRP, Anti-DNA double stranded AB's? Any of those tests been run yet? Why are your fingers permanently flexed, Lupus Anticoagulant? ...Read more

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Does cutaneous lupus always present with positive ANA? What other tests besides skin biopsy can tell?

See below: There is no single test for lupus. A person can have lupus without ANA. The following website provides information about diagnostic criteria for lupus. May I add that there experts for such disease at UPMC in Pittsburgh.

http://forums. Webmd. Com/3/lupus-exchange/resource/26 ...Read more

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Looking for autoimmune diseases to be sure don't have any. Had ana, lupus blood tests, crp, blood counts, all normal, what else can I get?

Looking for autoimmune diseases to be sure don't have any. Had ana, lupus blood tests, crp, blood counts, all normal, what else can I get?

Urinalysis: You have had the screening tests. If the urine is normal and you do not have a skin rash and fever, use you money instead for exercise and relaxation. ...Read more

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Female 11 year old fever + pain doctors tested her for some blood tests (ana) = negative anti ds DNA = 42.769 what we have to do?

Female 11 year old fever + pain doctors tested her for some blood tests (ana) = negative anti ds DNA = 42.769 what we have to do?

See details: You need to see a pediatric rheumatologist. Juvenile inflammatory arthritis needs to be ruled out. Speak with the doctor who ordered these tests. ...Read more

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Causes of chronic enthesitis at heel without injury? Have had flares of SI pain for 7 yr, but also have high titre ANA. All other blood tests normal.

Causes of chronic enthesitis at heel without injury? Have had flares of SI pain for 7 yr, but also have high titre ANA. All other blood tests normal.

Suspect spondyloarthropathywithout further information it's hard to say: Without further information it is hard to say. You had enthesitis but what studies have been done about the sacroiliac pain. Also your physician will have to do a lot more evaluation of your positive AMA and decide what subsets if any are positive. As you can see we will need more clinical and imaging information as well as laboratory information including HLA B 27 ...Read more

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Tested positive for ANA and now further tests show I'm also positive for ENA antibodies - sm b and rnc. Is it more likely to be mctd or sle? Thanks

Depends: We know false antibody results exists. It is up to your rheumatologist to interpret the test results in the context of your history, exam, and other lab findings. ...Read more

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Referred to nephrologist to see if kidneys contributing to hypertension. He ordered blood tests, including ANA. Why? What would it tell?

ANA: ANA or antinuclear antibody titers are typically used for screening for connective tissue disease, lupus or lupus like diseases that are typically affecting the kidneys in time. ...Read more

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If ANA and other blood tests for autoimmune diseases came negative, how do I know I do have one like autoimmune suppressor as doctor say?

Ask your doctor: Hashimoto's thyroidits is an autoimmune disease where there are antibodies to the thyroid gland. Other antibodies such as ANA may develop along with the thyroid antibodies, but only in some patients. Autoimmune suppressor - you may have misunderstood your doctor. ...Read more

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Negative ANA levels. High TBO tests (118 iu/ml). Negative TSH. Could I still have lupus? So frustrated with my results! Doc says hashimotos.

Negative ANA levels. High TBO tests (118 iu/ml). Negative TSH. Could I still have lupus? So frustrated with my results! Doc says hashimotos.

No but: Why are you not trusting your doctor's conclusion? By the way, did you mean high TPO instead of TBO? Was the TSH negative =zero or normal? None of these tests however pointed to lupus but were compatible with Hashimoto's with still normal thyroid function (normal TSH) eventually leading to hypothyroid status and thus requiring regular follow-up. ...Read more

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My february blood tests showed ANA 1:80, rnp positive, CRP 5.1, TSH 1.83 also sed rate 25, mpv 12.1 what does this mean?

My february blood tests showed ANA 1:80, rnp positive, CRP 5.1, TSH 1.83 also sed rate 25, mpv 12.1 what does this mean?

Just a screening: An "ana" is a blood test used to screen a person for the possibility of several autoimmune diseases. It is important to remember that this is a screening test and a positive result only indicates more testing may be warranted. No blood test is perfect, and getting to a diagnosis is usually much more complex than drawing blood. ...Read more

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24m muscle twitch in arm for a while. Worried could be ALS or something. Blood tests urine ANA test and so on all norm frustrated with no answers?

24m muscle twitch in arm for a while. Worried could be ALS or something. Blood tests urine ANA test and so on all norm frustrated with no answers?

Fasciculations: Twitching or vibrations under the skin are likely caused by fasciculations. Fasciculations are fine twitchings of the muscle fibres under the skin. This is usually most obvious when the muscle is at rest. It can be completely benign and not significant except as a nuisance. It is made worse by fatigue, caffeine, or a combination of both. See your doctor or a neurologist for a proper evaluation. ...Read more

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I have had positive ANA and high rnp tests, rosacea, multiple surgeries for massive scar tissue in multiple organs, interstitial cystitis, can I have sle?

I have had positive ANA and high rnp tests, rosacea, multiple surgeries for massive scar tissue in multiple organs, interstitial cystitis, can I have sle?

Many possibilities.: Lupus is certainly possible with +ana and high rnp, rosacea, but so are other diseases. Scleroderma can have +ana and fibrosis/scarring of many organs. Sarcoidosis also can have granulomas of many organs that can appear to be scars and purple lesions on the face, fingers, and knees and would need biopsy for diagnosis. Sjogren's syndrome also has high rnp, +ana, and dry eyes, mouth, and skin. ...Read more