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Doctor insights on: Ana Positive Lupus

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Ana screen, ifa positive a (negative) means?

Ana screen, ifa positive a  (negative)   means?

Nothing by itself: One person in four tests positive. The vast majority of these people have no problems. The clinical picture is key, and how high the titer is may be helpful. ...Read more

Ana (Definition)

An "ana" is a blood test used to screen a person for the possibility of several autoimmune diseases. It is important to remember that this is a screening test and a positive result only indicates more testing may be warranted. No blood test is perfect, and getting to a diagnosis is usually much more complex than drawing blood and looking at a number ...Read more


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Positive ana positive rnp low positive ccp positive dsdna can you tell me if this means lupus or mctd?

?: depends on the clinical picture as well, results point towards auto immune disorder, but need to be put in clinical context and follow up to commit to a diagnosis ...Read more

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Sm/rnp antibody- ANA choice- positive, speckled/titer: 1:1280; sm & rnp (done alone) negative; sm/rnp antibody (together?) positive 3.0 guessing mctd?

Sm/rnp antibody- ANA choice- positive, speckled/titer: 1:1280; sm & rnp (done alone) negative; sm/rnp antibody (together?) positive 3.0 guessing mctd?

Heads up: One of the things that's frustrating about these antibody tests looking for different connective tissue diseases is that they are difficult to do and are fraught with pitfalls. I suspect you've had at least one lab error to complicate your workup. Have you have a tube test for u1-rnp? Your clinical symptoms and signs actually tell more about your diagnosis ; best direction for treatment. ...Read more

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How about Ana screen positive, Ana titer (ifa) 1:80 Hi, and pattern speckled?

How about Ana screen positive, Ana titer (ifa) 1:80 Hi, and pattern speckled?

How about it?: Up to a quarter of women your age have an ANA (immunofluorescent antibody) at a low titer like yours with a speckled pattern. If there's a question of whether you have lupus or one of its relatives, it's a piece of information to note and file for future reference. A negative ANA would rule several things out. Your result proves nothing positive. Best wishes. ...Read more

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Av test positive .Ra factor positive .Joint pain .Ccp antibody test negative.Raised esr.Plz diagnose my disease.

Av test positive .Ra factor positive .Joint pain .Ccp antibody test negative.Raised esr.Plz diagnose my disease.

Cannot diagnose: Although these lab values are interesting, taken out of the context of your symptoms and findings on physical examination, plus further testing there is no way in which to diagnose over the internet. See a rheumatologist and get appropriately assessed. ...Read more

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ANA positive SSA SSB weekly positive SCL weekly positive RNP SM weekly positive. Any implications? What are the differential diagnosis? WaDoes it mean

ANA positive SSA SSB weekly positive SCL weekly positive RNP SM weekly positive. Any implications? What are the differential diagnosis? WaDoes it mean

Pos auto ab tests: You are describing positive tests for auto antibodies. The differential diagnosis can be extensive. I am assuming a rheumatologist has ordered these tests? You need f/u with them to educate you what they mean, what further tests may need to be done and review your symptoms. Proper rheum DX is not based only on test results, but exam findings and symptoms of patient. Good luck. ...Read more

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Ana test results 1:320 mean? Speckled homogeneous

Ana test results 1:320 mean? Speckled homogeneous

Not necessarily: The ANA is a screening test for lupus but is not specific. It can be positive in numerous other diseases and in normal people. It has to be evaluated in the context of the clinical picture and the results of other autoantibody tests. ...Read more

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Does highly elevated antinuclear antibody result always mean systemic lupus erythematosus?

Not always: Unfortunately, there is no single laboratory test that absolutely rules in or out systemic lupus erythematosis (sle). Although a highly positive antinuclear antigen (ANA) is common in sle, diagnosis is based on a careful history, physical exam and laboratory evaluation. ...Read more

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What does this mean ? SSB(La)IGG Positive 85 SSA(Ro)AB IGG Neg. ANA NEG. SED RATE Neg. CRP Neg. RF NEG.

Depends: All lab results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that antibodies to SSA suggest auto-immune disorder, however, if that is the only abnormal test and you do not have any symptoms, I would leave it alone and re-evaluate in six months. ...Read more

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Can ANA test be false negative for lupus?

Lupus: Has specific criteria for diagnosis, ANA is just one of them and canot be relied on by itself for a diagnosis. ...Read more

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(Biopsy DLE Inconclusive)ds-DNA Normal.Weak Positive ANA,ENA R Positive ANT RNP positive FBC &Urine Ok.Photosen,Rash face&Ears blister fingers... SLE?

(Biopsy DLE Inconclusive)ds-DNA Normal.Weak Positive ANA,ENA R Positive ANT RNP positive FBC &Urine Ok.Photosen,Rash face&Ears blister fingers... SLE?

No: DLE , even if you have it, does not necessarily translate into SLE in the absence of other system involvement. True blisters are not usually found with DLE. Have you been checked for porphyria? ...Read more

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Could fibromalagia cause ANA positive? 1:640 speckled and sed rate elevated? Lupus panel negative

NO: The ANA is there because of some other reason. Because it's there does not mean you have lupus. There are many other reasons to have a positive ana. Your evaluation by your physician can clarify. ...Read more

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What would cause a high positive ANA (1:640) speckled, nucleolar with a low positive smooth muscle antibody (1:40) but negative SS-A, SS-B, anti-Smith, RNP, SCL-70, Anti Jo antibodies? Liver disease?

Probably normal: Many people have a positive ANA without being sick. If you also have elevated liver enzymes, a workup for autoimmune hepatitis may be continued, but if there's nothing to suggest a liver problem biochemically, I'd not be in a hurry to diagnose despite anti-smooth-muscle. ANA means nothing apart from the clinical picture. Best wishes. ...Read more

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C reactive protein 0.81h Ana screen, IFA positive Ana pattern homogeneous Ana titter 1:80H What's wrong with me ?

Maybe nothing: C reactive protein is famously insensitive and nonspecific. Many young women have an ANA titer like yours. The diagnosis, if one is to be made, will be on history and physical exam. ...Read more