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Doctor insights on: Ana Positive Arthritis

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Mild Psoriasis sufferer, chronic pain right forarm & elbow. Blood tests 80 titre ana, positive anticentromere. Psoriatic arthritis or scleroderma?

Mild Psoriasis sufferer, chronic pain right forarm & elbow. Blood tests 80 titre ana, positive anticentromere. Psoriatic arthritis or scleroderma?

Occam's Razor: Usually Systemic Sclerosis and/or limited Scleroderma is not characterized by arthritis like you describe. The typical biomarker the anti Scl-70 (anti-topoisermorase). Symptoms have to be put into context and better described than elbow and forearm pain. This one you should see a rheumatologist about. Dermatology would be useful as well. Best of luck! ...Read more

Dr. Thomas Namey
2,400 doctors shared insights

Arthritis (Definition)

A condition where there is progressive degeneration of one or more joints. Symptoms may include joint pain, swelling, decreased motion, and stiffness. The two most common types of arthritis are osteoarthritis, which is associated first with articular cartilage breakdown with a component of inflammation, and rheumatoid arthritis, which is a systemic autoimmune disorder that affects joint linings first and secondarily ...Read more


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What is ANA positive means?

What is ANA  positive means?

Family practice : ANA , antinuclear antibody, testing is ordered to help detect auto immune disorders. It is a screening test and if positive prompts you to go further to detect causes. Lupus for one but there are others. ...Read more

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What does an ANA positive 1:40 nucleolar pattern mean?

What does an ANA positive 1:40 nucleolar pattern mean?

Probably nothing: Most rheumatologists consider an ANA titer of only 1:40 to really be a negative test. ...Read more

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I'm ana-positive; could I have lupus without any symptoms?

I'm ana-positive; could I have lupus without any symptoms?

See a Rheumatologist: This really needs to be discussed with a rheumatologist who can take a complete history and do a physical exam. In addition he or she will need to do additional laboratory tests before making the diagnosis of lupus or ruling it out. ...Read more

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Ana test results question - how many people have ANA positive but don't ever get lupus?

Age and gender: Positive ANA test is commoner in older people and women. Up to 25% of the people may have positive ANA test at some time or the other. Only 0.1-0.15% of the population has systemic lupus. ...Read more

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So confused 4 xs ANA positive low titers now I am negative how is that ENA always been negative?

It varies: ANA can vary and by itself does not make a diagnosis.I would not fret about it if you do not have symptoms to diagnose you with any particular autoimmune disease. ...Read more

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Saw rhumy for app.2. Sojourn ANA positive but not high.Lots of mixed symptoms. Starting plaquanil what does this mean exactly? Worst case and best

Saw rhumy for app.2. Sojourn ANA positive but not high.Lots of mixed symptoms. Starting plaquanil what does this mean exactly?  Worst case and best

See details: Plaquenil (hydroxychloroquine) is a basic theory for a number of the connective tissue disorders such as ra, lupus or sjogrens. It is well tolerated and has a relatively low risk of side effects. It is a good choice. ...Read more

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Ana positive 1.80 speckled, what does that mean?

Ana positive 1.80 speckled, what does that mean?

Often nothing: The ANA is not very specific. It can be positive in numerous diseases including viral diseases. It can also be positive in individuals without any disease. The ANA needs to be interpreted in the clinical setting to be properly evaluated. An ANA of only 1:80 is borderline at most. ...Read more

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Can you tell me what can ANA positive & rnp 1.1 mean?

Probably nothiung: If it is just the ANA screen that is positive, it means nothing. An rnp of that level definitely means nothing. Why wre the tests ordered in the first place? ...Read more

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What does this mean? Ana positive 1:80 and bordering rnp?

Probably nothing: These results are unimpressive and likely mean nothing. The results should be evaluated in the context of the clinical symptoms. Ask the doctor who ordered them if they mean anything. If unsure, see a rheumatologist. ...Read more

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After testing I have ANA positive and rnp positive (1.4). What could this mean? ?

Context: If the titers are both 1:4 and you do not have obvious lupus or mixed connective tissue disease, then i'd bet they mean little or nothing. Diagnosis in rheumatology is based on history and physical exam, with labs just for confirmation. ...Read more

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Ana positive twice 1:40 speckled and again 1:160 atypical speckled and nucleolar what is the atypical speckled?

Indicator of antibod: The speckled pattern represents different types of antibodies in your nucleus. These can go with variety of nucleoprotines such as rnp, smith, ssa, ssb. The nucleolar pattern is the staining of the nucleolus a certain defined structures inside the nucleus. These can be associated with a variety of specific connective tissue disease but may not also. A evaluation of you will tell. ...Read more

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Hemoglobin has been low in the 12.- area also ANA positive than my hemoglobin went to 13.1...My question is since it's back normal is the ANA moot?

Not necessarily: A low level ANA may not cause any disease and it would help to know the titer/level of antibody and the type of ANA you have. It is good that hemoglobin has increased but that may not have been related to ana. All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. ...Read more

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I know you get this a lot, but i had ANA positive 1:80 speckled. I kind or know that these can be a false positive.What dose the flag a & range n mean?

I know you get this a lot, but i had ANA positive 1:80 speckled. I kind or know that these can be a false positive.What dose the flag a & range n mean?

ANA titer matters.: ANA, or anti-nuclear antibody, is a a sensitive and specific test for systemic lupus erythematosus ONLY at high titer >1:320. Up to one in ten HEALTHY women can have a positive low-titer ANA, 1:40 or 1:80, which does NOT indicate lupus. Only a high-titer ANA can be used to diagnose lupus. To measure clinical activity in lupus, a different antibody called anti-double stranded DNA is measured. ...Read more

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Is a ANA positive when u have temporal artertis if its a immune problem too?

No: The histopathology and the little bit we know of how the disease works indicates it's a cell-mediated rather than an antibody-mediated problem. ...Read more

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Ana positive result (1:1280) in blood tests. All other blood tests normal. What could that mean?

Ana positive result (1:1280) in blood tests. All other blood tests normal. What could that mean?

Risk: That may mean you are at higher risk to develop an autoimmune disorders in the future. Since you are suffering from back pain already at your young age, perhaps you should see a rheumatologist to find out if there is any autoimmune disorder affecting your back unless the cause for the back pain is already known. ...Read more

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Does ANA 1:320 make diagnosis of RA more definitive? My RF was negative but I have multiple symptoms over 6 months. ANA positive 1:320

No: ANA actually isn't something we expect to be positive in rheumatoid arthritis. Your physician is thinking about lupus as a possible explanation, I'll bet. I'm sorry you're having this illness and difficulty in getting diagnosed, but this is common. Usually the nature of a systemic immune disease such as lupus or RA becomes clear over time unless it remits on its own. ...Read more

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I was diagnosed with mono yesterday. Is it possible to have this a whole year? Guess that would explain ANA positive and high sed rate.

Mono is not a likely: Explanation for the symptoms lasting a year and ANA and sed rate abnormalities. Infectious mono is not a usual cause of an illness lasting longer than 4 months. See this site for more info. http://www.cdc.gov/ncidod/diseases/ebv.htm. ...Read more

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Rough year . Ana positive 1;640 sed rate 30. When i visit the drs and randomly throughout day my temp is elevated off and on. Never over 99.9. ?

Autoimmune disease: A positive ANA can occur in autoimmune disorders, which can affect many organs including joints, musculoskeletal system, kidneys, liver, salivary glands, thyroid and many more. A thorough work up with your internal medicine doctor and appropriate specialist may be needed. The sed rate and fevers may all be related to the inflammation associated with possible autoimmune disorders. ...Read more

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ANA positive SSA SSB weekly positive SCL weekly positive RNP SM weekly positive. Any implications? What are the differential diagnosis? WaDoes it mean

ANA positive SSA SSB weekly positive SCL weekly positive RNP SM weekly positive. Any implications? What are the differential diagnosis? WaDoes it mean

Pos auto ab tests: You are describing positive tests for auto antibodies. The differential diagnosis can be extensive. I am assuming a rheumatologist has ordered these tests? You need f/u with them to educate you what they mean, what further tests may need to be done and review your symptoms. Proper rheum DX is not based only on test results, but exam findings and symptoms of patient. Good luck. ...Read more

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Please can someone explain these ANA results - ANA positive (centromere 0.2) an ENA revealed positive ssa and ssa60 (4.5) I am grateful for any advice?

Sjogrens Syndrome: Anti centromere antibody is associated with limited scleroderma. A positive ANA and ss-a, ss-b antibodies are associated with sjogrens syndrome. These tests are not diagnostic by themselves and have to be evaluated along with your symptoms and physical examination to get a definite diagnosis. ...Read more

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Tested ANA positive. What exactly does this mean?

Not much alone: A positive antinuclear antibody test can be found in normal people or diseases, and as such doesn't mean much by itself. You need a thorough history and physical exam and tests if indicated to know what this means. ...Read more

Ana (Definition)

An "ana" is a blood test used to screen a person for the possibility of several autoimmune diseases. It is important to remember that this is a screening test and a positive result only indicates more testing may be warranted. No blood test is perfect, and getting to a diagnosis is usually much more complex than drawing blood and looking at a number ...Read more


Dr. Robert Lowe
1,537 doctors shared insights

Painful Joints (Definition)

That term is not really a specific diagnosis, but rather somewhat of a general term. The medical term is arthralgias, which implies pain in multiple joint possibly coming from a single cause. Don't hesitate to be seen and evaluated for ...Read more