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Doctor insights on: Ana Ifa Screen

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Dr. Ronald Krauser
3 doctors shared insights

Ana Ifa Screen (Overview)

Anti-nuclear antibodies (anas) are autoantibodies directed against certain parts of a cell nucleus. Anas are present in increased amounts in a variety of autoimmune diseases. An ANA test measures the pattern and amount of these autoantibodies that can attack the body's tissues as if they were foreign. An indirect fluorescent antibody (ifa) test is one that uses two antibodies for detection.


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I have a lab result of positive ANA screen, ifa. Ana pattern is speckled and ANA tilter is 104H. Is this of concern. Have fingers and toes draw up.

I have a lab result of positive ANA screen, ifa.  Ana pattern is speckled and ANA tilter is 104H. Is this of concern.  Have fingers and toes draw up.

Big picture: About one grown woman in four has detectable antinuclear antibodies. They are only on part of the workup for your back pain / fatigue. For most people, they are of no consequence. They are of course the basic screening test for lupus and for a few other illnesses, but you're not a lupus patient yet. Best wishes -- stay proactive and keep asking these good questions. ...Read more

Dr. Ronald Krauser
3 doctors shared insights

Ana Ifa Screen (Overview)

Anti-nuclear antibodies (anas) are autoantibodies directed against certain parts of a cell nucleus. Anas are present in increased amounts in a variety of autoimmune diseases. An ANA test measures the pattern and amount of these autoantibodies that can attack the body's tissues as if they were foreign. An indirect fluorescent antibody (ifa) test is one that uses two antibodies for detection.


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What is the definition or description of: ANA ifa screen?

What is the definition or description of: ANA ifa screen?

A lab test.: Anti-nuclear antibodies (anas) are autoantibodies directed against certain parts of a cell nucleus. Anas are present in increased amounts in a variety of autoimmune diseases. An ANA test measures the pattern and amount of these autoantibodies that can attack the body's tissues as if they were foreign. An indirect fluorescent antibody (ifa) test is one that uses two antibodies for detection. ...Read more

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Positive ANA IFA screen with reflex is it contagious?

Antibodies: A positive ANA means antibodies which can react with your body's cells. They can form after an infection, but do not indicate anything about the infection which is usually long since gone. There are many, many people whose ANA is positive and very, very few who have actual autoimmune disease. The question to ask is: for what symptoms was the ANA ordered? ...Read more

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What does a positive ANA screen ifa and dual ANA pattern mean?

What does a positive ANA screen ifa and dual ANA pattern mean?

ANA : ANA test is a screening test to diagnose auto immune diseases especially lupus. ANA stands for anti nuclear anti bodies directed against nuclear components called antigens. Ifa stands for immuno fluorescent assay .There patterns that develop based on which anti body is directed against which antigen and such patterns are called homogenous , nucleolar etc signifying different disease patterns. ...Read more

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Ana screen, ifa positive a (negative) means?

Nothing by itself: One person in four tests positive. The vast majority of these people have no problems. The clinical picture is key, and how high the titer is may be helpful. ...Read more

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What is the difference between the anachoice screen and the ANA screen, ifa? The first one came back positve, but the second came back negative.

IFA better: For a screen the ifa is much better. It is the gold standard. The ANA choice is not a screening test and should not be offered as a screening test. Your question is somewhat counter intuitive. The ifa is a better test and if choice is positive - it can be subseted into 12 antigens and the lab can tell you. I would follow your test results with ANA subsets per your rheumatologist. ...Read more

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What is the difference between the anachoice screen and the ANA screen, ifa? The first one came back positve, but the second came back negative.

What is the difference between the anachoice screen and the ANA screen, ifa? The first one came back positve, but the second came back negative.

Diff. lab techniques: Different labs have different ANA tests, which is a test for antibodies a person makes that attach to his own body's tissues, that end up causing auto-immune disease. Modern tests use "reflex" or "cascade" techniques, meaning one test is done first, and then if positive, another test is done, and then if positive again, a third test is done. Tests have various "positive" ranges (gets complicated). ...Read more

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C reactive protein 0.81h Ana screen, IFA positive Ana pattern homogeneous Ana titter 1:80H What's wrong with me ?

Maybe nothing: C reactive protein is famously insensitive and nonspecific. Many young women have an ANA titer like yours. The diagnosis, if one is to be made, will be on history and physical exam. ...Read more

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I have a lab result of positive ANA screen, ifa. Ana pattern is speckled and ANA tilter is 104H. Is this of concern. Have fingers and toes draw up.

Big picture: About one grown woman in four has detectable antinuclear antibodies. They are only on part of the workup for your back pain / fatigue. For most people, they are of no consequence. They are of course the basic screening test for lupus and for a few other illnesses, but you're not a lupus patient yet. Best wishes -- stay proactive and keep asking these good questions. ...Read more

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How about Ana screen positive, Ana titer (ifa) 1:80 Hi, and pattern speckled?

How about it?: Up to a quarter of women your age have an ANA (immunofluorescent antibody) at a low titer like yours with a speckled pattern. If there's a question of whether you have lupus or one of its relatives, it's a piece of information to note and file for future reference. A negative ANA would rule several things out. Your result proves nothing positive. Best wishes. ...Read more

Ana (Definition)

An "ana" is a blood test used to screen a person for the possibility of several autoimmune diseases. It is important to remember that this is a screening test and a positive result only indicates more testing may be warranted. No blood test is perfect, and getting to a diagnosis is usually much more complex than drawing blood and looking at a number ...Read more