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Doctor insights on: Amylase And Lipase Levels In Pancreatic Cancer

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Are normal cbc, billuprin, amylase and lipase levels, CT scan and qualitative fecal fat test a good indication against pancreatic cancer?

Are normal cbc, billuprin, amylase and lipase levels, CT scan and qualitative fecal fat test a good indication against pancreatic cancer?

Yes: Pancreatic cancer is most uncommon at your age to begin with (it is not a common cancer in general). Normal blood tests and ct scan should reassure you that pancreatic cancer is not there. ...Read more

Dr. Barry Rosen
4,351 Doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


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Would amylase and lipase be high or low with pancreatic cancer?

Amylase and lipase: Are usually elevated with inflammation such as pancreatitis and could be normal with pancreatic cancer. A tumor marker ca 19-9 is usually elevated with pancreatic tumors. Depending on the location of tumor biliary enzymes could be elevated too. ...Read more

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Mom has jaundice w elevated liver enzymes, and elevated amylase and lipase. Ct w contrast was done, no tumors seen. Could this be pancreatic cancer?

Mom has jaundice w elevated liver enzymes, and elevated amylase and lipase. Ct w contrast was done, no tumors seen. Could this be pancreatic cancer?

It is unclear: Hi kitten40047. The jaundice and elevated enzymes are concerning. It is reassuring to hear that the ct was negative. There may be other reasons for her symptoms. However, in the absence of any other explanation for the symptoms she has, you may want to have mom undergo additional tests, including perhaps MRI or endoscopy, which may shed more light on the pancreatic and liver areas. ...Read more

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When lipase levels do elevate because of pancreatic cancer, how high do the levels tend to get? Very high or just slightly elevated?

When lipase levels do elevate because of pancreatic cancer, how high do the levels tend to get? Very high or just slightly elevated?

May/may not. Unrelia: Lipase is not a reliable test for making a diagnosis of Pancreatic Cancer. It is test which is largely limited in its usfulness, mostly for cases of pancreatitis. ...Read more

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I am still so anxious about having pancreatic cancer. My lipase levels have fluctuated slightly over the past year - from 1 to 20 points over the reference range. I've had normal ultrasound and CT scan. Dr seems to think it's just me. But why??

I am still so anxious about having pancreatic cancer. My lipase levels have fluctuated slightly over the past year - from 1 to 20 points over the reference range. I've had normal ultrasound and CT scan. Dr seems to think it's just me. But why??

Lipase barely high: 33 F anxious re pancreatic CA. Notes lipase has fluctuated slightly 1 yr. 1 to 20 points over norm. US&CT scan OK. Dr seems to think it's just me. ANS: I agree with Dr. Norm means 95% of normals are in n range but 5% aren't. Suspect you are in the 2.5% upper. All lab tests can vary 10% day to day. So if ur reading is 200 then expect it to vary by 20. Recommend u worry about other things. ...Read more

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Can pancreatic enzymes with protease, amylase and lipase hurt or help cancer?

Health fraud: Giving the pancreatic enzymes that help in pancreatic insufficiency (cystic fibrosis, chronic pancreatic scarring) as a cancer treatment is a cynical, cruel fraud. It's often packaged with "detoxification" and coffee enemas. Don't pay money to the people who've tried to deceive you on the thought "what if it did work? ". ...Read more

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Which test is better for diagnosing pancreas insufficiency: stool panc elastase or serum lipase/amylase? Would either diagnose pancreatic cancer?

Which test is better for diagnosing pancreas insufficiency: stool panc elastase or serum lipase/amylase? Would either diagnose pancreatic cancer?

Both together: Neither of the tests alone tells much. A combination of tests and exams will lead to diagnosis. Pancreatic cancer is not able to be ruled out by any test or imaging study. It can only be absolutely proven by some form of biopsy. A ct guided needle or egd with brushing a may be the only way to find it. ...Read more

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If someone has chronic pancreatitis, will their amylase and lipase levels always be elevated? Or only during flare ups?

Not Necessarily: Serum amylase and lipase may or may not be elevated in cases of chronic pancreatitis, depending on the severity of inflammation and cell damage. Of the two, lipase is more likely to mildly elevated. While lipase is specific to the pancreas (amylase comes from other sources), both are commonly elevated in cases of acute pancreatitis. ...Read more

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Pain RUQ-x6mos- dr says gall bladder but HIDA, CBC, CMP, lipase, amalyse, EGD and abdom US 6m ago nml- can this pancreatic cancer? 30 yo. No Weight loss

Pain RUQ-x6mos- dr says gall bladder but HIDA, CBC, CMP, lipase, amalyse, EGD and abdom US 6m ago nml- can this pancreatic cancer? 30 yo. No Weight loss

No...Second opinion: Not likely to be pancreatic cancer given the imaging you've had so far. There is a blood test you can get that you that might be reassuring. I suggest a second opinion to evaluate for something more usual such as sphincter dysfunction. In the meantime avoid foods that induce symptoms ...Read more

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My lipase level is very low, amylase normal, left upper pain, light stools, CT is negative, pancreatic insufficiency maybe? Started 3wks ago.

My lipase level is very low, amylase normal, left upper pain, light stools, CT is negative, pancreatic insufficiency maybe? Started 3wks ago.

Doubt pancreas: If you've got pancreatic insufficiency, you'll be able to tell that you're seriously sick. The light stools of biliary and pancreatic duct insufficiency aren't just pale, they look like clay. You'd also have obvious weight loss and diarrhea by now. You'll be followed, early gluten enteropathy is a possibility and there are a host of others. ...Read more

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If mid back and abdominal discomfort were caused by pancreatic cancer, would not blood work be off in CBC, amylase, or lipase in a 27 yo male?

If mid back and abdominal discomfort were caused by pancreatic cancer, would not blood work be off in CBC, amylase, or lipase in a 27 yo male?

See below: Blood test results may be normal in a person with pancreatic cancer.
You, at 27, are unlikely to have pancreatic cancer.
For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Drink enough water daily, so that your urine is mostly colorless. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form.
Practice safe sex. ...Read more

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What is the usual level of lipase in someone with pancreatic cancer? How elevated does it get?

What is the usual level of lipase in someone with pancreatic cancer? How elevated does it get?

Poor test for cancer: Lipase is usually not elevated in Cancer arising from the Pancreas...so it is not a test we do to check for Cancer. Lipase and Amylase are tests done to make a diagnosis of Pancreatitis ...Read more

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Would an abdominal ultrasound, amalyse/lipase blood test, reveal pancreatic cancer or even hints it?

Would an abdominal ultrasound, amalyse/lipase blood test, reveal pancreatic cancer or even hints it?

Blood test no help: Ultrasound may point to the presence of mass that would need to investigated further to rule in or rule out cancer. The blood test you listed are not helpful in the diagnosis of cancer. ...Read more

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Had slightly elevated lipase (80 when normal reference range was 13-60). I'm terrified of pancreatic cancer! I'm only 33! ?

Lipase, not reliable: Lab tests are only done if the doctor suspects something, based on your symptoms. So you need to tell us why was this test done? Did the ordering doctor tell you what may be wrong and what the Lipase test means? It is important to tell us the complete story!
Basically Lipase is not a particularly useful test and rarely helps in making any diagnosis. So it is not likely to indicate Cancer at all. ...Read more

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My labs came back should I be worried my lipase are elevated to 59, wondering what could it be. Hoping its not pancreatic cancer?

My labs came back should I be worried my lipase are elevated to 59, wondering what could it be. Hoping its not pancreatic cancer?

Why was it tested?: That's the most important question to ask. The context in which the lab was drawn will inform how it is interpreted. Lots of things can raise your lipase (e.g. Alcohol use, gallstones, medications, etc.) while pancreatic cancer is a (remote) possibility, have a positive attitude and follow up with your doctor. They can better help interpret the test. 59 is normal in my hospital, btw. ...Read more

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Is elevated lipase and A1C of 5.8% an early sign of pancreatic cancer for someone who is slim and has great uncle who died from disease.

Elevated lipase: Elevated lipase is usually as sign of pancreatitis (acute or chronic) caused by a variety of factors (too much alcohol; too much starch/sugar consumption; excessive fat intake; smoking, obesity, etc). It is not a sign of pancreatic cancer ...Read more

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If steatorrhea is caused by pancreatic cancer, will a lipase blood test show abnormalities?

If steatorrhea is caused by pancreatic cancer, will a lipase blood test show abnormalities?

Not really: Brother Fadi.
steatorrhea is not caused by pancreatic cancer, but by pancreatic deficiency.
the pancreatic enzyme, and function could be completely normal in the case of cancer.
I hope that answer your concerns.
fi amani Allah. ...Read more

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My A1C is climbing from 5.6 to 5.8 in over 1 year. I also have fluctuating lipase numbers without symtoms. This has been going on 4 years. MRCP clear. Does this sound like early pancreatic cancer?

My A1C is climbing from 5.6 to 5.8 in over 1 year. I also have fluctuating lipase numbers without symtoms. This has been going on 4 years. MRCP clear. Does this sound like early pancreatic cancer?

Panc Ca: The change in A1C is not significant. Its unlikely you have pancreatic cancer. But if you are concerned get a CT of the abdomen. (However, we now know that CT scans can significantly increase the risk of a number of cancers.) ...Read more

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If pancreatic cancer was the cause of mildly elevated lipase, would the tumor likely be big enough to be seen on a CT scan?

If pancreatic cancer was the cause of mildly elevated lipase, would the tumor likely be big enough to be seen on a CT scan?

Possibly: This enzyme, produced by the pancreas to break down triglycerides can result from any physiologic changes in the pancreas ranging from mild to sever pancreatitis to carcinoma of the pancreas. Mild inflammation is not seen on CT scan ...Read more

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Elevated lipase lab value 180/290 mine 309, 329 then 369 on Lipitor (atorvastatin), mother passed at 84 pancreatic cancer no family history I'm so scared.?

Not enough info: By itself this number can not tell a doctor if there is a problem. This elevation is not that impressive. If you have concerns, see a surgeon or a GI for further blood work or just a discussion to see if you have any signs of a problem. Once again, lipase alone is not enough ...Read more

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Can gallstones cause only lipase levels to elevate (and not amylase)?

Depends: If and where gallstones are obstructing biliary system. If gallstones obstruct pancreatic duct and inflame pancreas, both Lipase and Amylase levels can rise, but Lipase is a more specific and accurate measure of pancreatic damage. ...Read more

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What can cause amylase & lipase levels to slightly elevate? They weren't too high like norm is under 300 it was 332. All rad tests are negative!

More than a little: Elevated. Elevations of amylase and lipase are usually due to pancreatic damage, and some times due to intestinal obstruction, renal failure. X-ray is not the most sensitive diagnostic tool for pancreatic lesions. Do you drink; or have gall stones? It would be prudent to consult a gasto-enterologist for a proper workup for your level of enzyme elevations. ...Read more

Dr. Todd Igel
359 Doctors shared insights

Lipase (Definition)

Lipases, such as lipoprotein lipase and endothelial lipase, are enzymes that breakdown circulating triglycerides (tg). Specifically, lipases degrade tg rich lipoproteins including chylomicrons, very low density lipoprotein (vldl) and remnant particles produced by breakdown of chylomicron and vldl particles. Decreased lipase function leads to accumulation of ...Read more


Dr. Heidi Fowler
3 Doctors shared insights

Pancreas (Definition)

Abdominal organ. It is digestive organ: it secretes enzymes into the small bowel which break down food and help its absorption. It is also an endocrine organ: it produces hormones involved in sugar control and control of digestion. Insulin is one of these hormones. Diabetics either lack Insulin (type 1 diabetes) or have inadequate ...Read more