Doctor insights on:
Amniotic Fluid Test
I had an amniotic fluid test which showed a high concentration of alpha-fetoprotein. What does this mean?
Oligohydramnios: Low amniotic fluid or oligohydramnios is a condition brought about by a decreased production of urine by the fetus either through a decreased placental perfusion or blocked urinary outlet, to name a few. It could also result from a ruptured amniotic membrane. One of the first signs of low fluid is a size-date discepancy of the growing uterus. An ultrasound will help to diagnose the condition. ...Read moreSee 1 more doctor answer
I had done triple test on 18th week n result shows 810:1risk.Do I need to take amniotic fluid test.please suggest.
No: A 1:810 risk isn't very high. I wouldn't recommend an amniocentesis. I don't know what cut-off is used in China. In the USA, Amnio is frequently recommended if the triple-screen risk is greater than the risk of a 35 year-old women (once chance in 365) The UK frequently uses a cutoff of greater than once chance in 150. ...Read more
5 months pregnant. On amniotic fluid sample test, "fetal karyotype was found to be 47, ##, +21 indicating down syndrome.". Should i go for abortion?
Personal decision: Yes, your child has down's syndrome. I have no idea how those children are treated in india. However, they are the most loving, kind people i care for. They have the capacity for love and joy unlike any of my other patients. Will the child require extra care and have different needs - absolutely. Only you can decide if you have the capacity to provide this and continue the pregnancy. ...Read moreSee 1 more doctor answer
Rapid look for Down.: Fish stands of fluorescent in-situ hybidization of the chromosomes in fetal cells obtained after invasive prenatal diagnosis (such as amniocentesis). When time is of the essence, fish can give a preliminary result of fetal aneuploidy (e.g. Down syndrome) within 24 hours from the procedure. It should be followed by a full karyotype and chromosomal microarray analysis. ...Read more
Ultrasound at 40weeks today showed AFI 28cm. Excess amniotic fluid? All scans until now had normal amount. Should I worry? Glucose test was normal.
High: The AFI is a little above high normal. There can be several causes, including human error on how they measured. You say ALL scans, why were they doing more than one scan during you pregnancy. There must have been other concerns going on. But, since all were normal until now, I would suggest this is still a low risk finding. Speak with your OB for final interpretation. ...Read more
Clinical and DIC: Amniotic fluid embolism, depending on the amount of fluid getting into maternal circulation can be catastrophic. The diagnosis depends on clinical suspicion and testing for disseminated intra-vascular coagulation, namely low platelet count, elevated pt ptt, abnormal shape of red cells, low fibrinogen and fibrin split products, chest x-ray etc. ...Read more
Amniocentesis: The diagnosis is suggested by severe abdominal pain, decreased fetal movement, and maternal fever. The definitive test is amniocentesis, which is to obtain a sample of fluid, usually under ultrasound guidance, and then sending the fluid for appropriate laboratory studies. This is a very serious condition that, if confirmed, almost always requires delivery of the baby. ...Read more
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