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Doctor insights on: Amitriptyline Uses Other Than Depression

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Dr. Pamela Pappas
4,588 doctors shared insights

Depression (Definition)

Depression is a mood disorder that can affect behavior and emotions. Symptoms of depression include feeling down most of the time, losing interest in previously enjoyable activities, increase or decrease in appetite or weight, sleeping more or less, becoming easily agitated or lethargic, feeling worthless, feeling guilty, having difficulty concentrating, thinking more about death and dying. Depression can sometimes result in suicidal thoughts and plans. In this case, emergent ...Read more


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How effective is amitriptyline for treating depression?

How effective is amitriptyline for treating depression?

Elavil (amitriptyline): Is an antidepressant with sedating and drying effects, causing heart rate changes, dry mouth/eyes, constipation, depending on dose. It relieves depression, pain of neurogenic origin, headache and insomnia. Can also be used at low dose for Nocturnal enuresis. ...Read more

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How effective is Elavil (amitriptyline) for treating depression?

How effective is Elavil (amitriptyline) for treating depression?

Elavil (amitriptyline): Is an antidepressant with sedating and drying effects, causing heart rate changes, dry mouth/eyes, constipation, depending on dose. It relieves depression, pain of neurogenic origin, headache and insomnia. ...Read more

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Why is elavil (amitriptyline) supposed to help depression when it sometime can cause it?

Why is elavil (amitriptyline) supposed to help depression when it sometime can cause it?

In addition, : True. Elavil (amitriptyline) is not used as antidepressant that often anymore. As a tricyclic, therapeutic doses leads to problematic sidd effects (e.g., sedation, weight gain, dry mouth, etc.). However, Elavil (amitriptyline) at loeer doses is commonly used in pain management and as a non-addictive sleep aid. ...Read more

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Is elavil (amitriptyline) supposed to be taken for sleep, for depression, or for pain?

Is elavil (amitriptyline) supposed to be taken for sleep, for depression, or for pain?

Elavil (amitriptyline): Elavil (amitriptyline) may be used for pain and depression, one of the side effects is somnolence so it helps with sleep problems as well. ...Read more

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I've been prescribed mirtazapine for depression and amitriptyline for pain. Is it okay to be on both?

I've been prescribed mirtazapine  for depression and amitriptyline for pain. Is it okay to be on both?

Just take one.: Both can cause mouth dryness/constipation & both are sedating anti-depressants. Would prefer mirtazapine although you did not really provide details of what type of depression you have. If you really need to continue amitriptyline, would suggest SSRI like sertraline instead of mirtazapine in AM to counteract the constipation side effect of amitriptyline. ...Read more

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How long does it usually take elavil (amitriptyline) to work for chronic pain and depression together?

How long does it usually take elavil (amitriptyline) to work for chronic pain and depression together?

A lot: Although Elavil (amitriptyline) is an antidepressant, the medicine is out of traditional repertoire for depression. Very high dose will be required, and may be poorly tolerated. ...Read more

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I'm 3 days in to taking 10mg of amitriptyline for IBS and i'm having bad depression and dizzyness. Will the side effects get better? If so when? Thnx

I'm 3 days in to taking 10mg of amitriptyline for IBS and i'm having bad depression and dizzyness. Will the side effects get better? If so when?  Thnx

Amitriptylene: Amitriptylene is an antidepressant whose side effects can help ibs -- especially when bowel activity is overactive. It can also cause changes in blood pressure when standing up from a lying position. This may dissipate in a few more days. Taking it at bedtime may help alleviate this & any sedating effects too. Please tell your doctor about any increase in depressive symptoms though! ...Read more

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Can I please get a prescription for elavil (amitriptyline)? I suffer from depression also anxiety.

Can I please get a prescription for elavil (amitriptyline)? I suffer from depression also anxiety.

Elavil (amitriptyline): Prescription medications can only be dispensed after face-to-face contact with the doctor. Sorry. ...Read more

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I take 150 mg. Amitriptyline at night for anxiety and depression. Does drinking caffeine takes away the benefits of the medication?

I take 150 mg. Amitriptyline at night for anxiety and depression. Does drinking caffeine takes away the benefits of the medication?

Can add to anxiety: Caffeine doesn't alter the antidepressant effect of Elavil (amitriptyline), but it can cause or worsen anxiety. So in that sense it could counteract the effect of the medication. Low to moderate amounts of caffeine shouldn't be a problem unless you're fairly sensitive to it, but on general principles i advise anxious patients to minimize caffeine. ...Read more

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Which is better for anxiety disorer ,depression,panic attack and help you gain weight, amitriptyline or remerom?

Which is better for anxiety disorer ,depression,panic attack and help you gain weight, amitriptyline or remerom?

Horse racing: Picking the winner is not possible. Each medication works well for some and causes problems for others. Your doctor may know you well enough to make a good choice or may need to refer you to a trained specialist. This is not a D.I.Y. type project - you need to be monitored and note that CBT therapy always optimizes medication effectiveness. Best! ...Read more

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I want to know how many milligrams of amitriptyline equivalent to 75 of sertraline for the treatment of severe depression...

I want to know how many milligrams of amitriptyline equivalent to 75 of sertraline for the treatment of severe depression...

Not exactly what: you asked - but 98.5 of sertraline equivalent to 122.3 of amitrypline. I don't think that this is a useful equivalent now adays. The reason is that the dose of amitryptyline needed to tx depression would be high enough that side effects may not be tolerable.

https://www.nationalelfservice.net/treatment/antidepressants/dose-equivalents-antidepressants-standardising-prescribing-different-drugs ...Read more

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I'm taking Amitriptyline HCL 25 mg at night for Depression, TMJ pain, and insomnia. My Dr is over 2 hrs away and I think I need an increased dosage?

Face-to-face: Unfortunately TCA (Amitriptyline ) medication monitoring must be done face-to-face or via video conferencing. The only allowable exception is when a patient is experiencing adverse symptoms from psychotropic medication and phone consultation with another professional is necessary. Call your doctor for appointment. ...Read more

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I take levothyroxine 50mcg in morning for hypothyroidism - safe to take 10mg amitriptyline at bed for depression? I've heard there's an interaction.

I take levothyroxine 50mcg in morning for hypothyroidism - safe to take 10mg amitriptyline at bed for depression? I've heard there's an interaction.

Epocrates no interac: Epocrates shows no interactions between levothyroxin and amitriptyline. Even if there were, it would be likely to be insignificant due to the low dose of Amitriptyline that you are taking. No need to worry. Have a good night. ...Read more

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I have gad and depression, why does my doc want me to take elavil (amitriptyline) during the day and before bed instead of just before bed? Many thanks

Duration : The duration of action of Amitriptyline is ~18 hours and is usually dosed once daily. Using it twice a day may be to prevent side effects. Please ask your doctor why this is being done in your case. ...Read more

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I was given 10mg Elavil (amitriptyline) for insomnia. Read up on drug, its an antidepressant. I don't have depression. Will this drug alter my mood or make me weird?

I was given 10mg Elavil (amitriptyline) for insomnia. Read up on drug, its an antidepressant. I don't have depression. Will this drug alter my mood or make me weird?

Weird, huh?: You didn't read far enough: You didn't read the information on indications and dosage. Antidepressant doses are at least 75-100 mg/d. It's also used for migraine at lower doses. It causes drowsiness, hence its use for sleep, but 10 mg is such a low dose it may have no effect on you at all, or lose what effect it does have after a week or so. It's usual to escalate the dose gradually to 30-50 mg/d. ...Read more

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Is it okay if I take small dose amitriptyline (25mg) for neuropathic pain and regular dose of citalopram for depression and OCD ?

Is it okay if I take small dose amitriptyline (25mg) for neuropathic pain and regular dose of citalopram for depression and OCD ?

Use Caution : The combination of these drugs can be used Important to check with your doctor .combining these medications can cause Serotonin syndrome such as confusion hallucinations and even seizures changes in blood pressure increase heart rate fever , excessive sweating blurred vision muscle spasms nausea vomiting and tremors. There may be alternatives you can use check with your doctor. ...Read more

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Can i take 150 mg elavil (amitriptyline) for depression and 25 mg. Of trazadone to help me sleep. Elavil (amitriptyline) alone doesn't help me fall asleep?

Can i take 150 mg elavil (amitriptyline) for depression and 25 mg. Of trazadone to help me sleep. Elavil (amitriptyline) alone doesn't help me fall asleep?

Yes: While Elavil (amitriptyline) can be good for sleep, sometimes people need more as a sleep aid. Trazodone 25 mg is a very low dose, and if it helps with your sleep, there is no problem taking it together with your elavil (amitriptyline). ...Read more

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Which meds is better amitriptyline or seroquerl or Prozac (fluoxetine). I have depression, anxiety disorder, panic disorder, dr has change meds 5 times now?

Which meds is better amitriptyline or seroquerl or Prozac (fluoxetine). I have depression, anxiety disorder, panic disorder, dr has change meds 5 times now?

Can't say: The 'best' one is the one that works for you. Unfortunately it is difficult to predict how people will respond to psychoactive medications and medication changes are not uncommon. Once someone has tried (honest effort of at least a few weeks) several medications without the desired response, a re-evaluation of the original diagnosis should be considered. ...Read more

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I'm on elavil (amitriptyline) 25 yrs.150 mg. For depression & anxiety-xanax on & off could i switch to ssri. I'd need ssri w/ sedative effect like elavil (amitriptyline) - recommend?

I'm on elavil (amitriptyline) 25 yrs.150 mg. For depression & anxiety-xanax on & off could i switch to ssri. I'd need ssri w/ sedative effect like elavil (amitriptyline) - recommend?

Options are availabl: Alternatives to xanax (alprazolam) are available. Discuss options with your physician. Abrupt unsupervised discontinuation of high regular xanax (alprazolam) doses can lead to withdrawal symptoms and possibly seizures. ...Read more

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Recently i just know that I am anemic , is it ok to take amitriptyline 5mg, Xanax (alprazolam) 0.25 mg and sangobion. I have a bit depression and panic attack.

Anemia and mood: I don't know the last medication you mentioned but otherwise it's okay. Treating the cause of your anemia will help your mood issues. ...Read more

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Is Imipramine with Buspirone a good option to treat social anxiety & depression if sertraline,duloxetine, venlaflaxine,amitriptyline haven't helped ?

Is Imipramine with Buspirone a good option to treat social anxiety & depression if sertraline,duloxetine, venlaflaxine,amitriptyline haven't helped ?

Caution: Imipramine + buspirone may interact to increase risk for serotonin syndrome. Be sure you are closely supervised by prescribing doctor while taking these meds. Imipramine alone is effective for both depression and anxiety. See: http://www.mayoclinic.org/diseases-conditions/serotonin-syndrome/basics/definition/con-20028946 I hope this helps. Best wishes. ...Read more

Dr. Jeffrey Satinover
379 doctors shared insights

Elavil (Definition)

Elavil is a tertiary amine tricyclic which is a kind of tricyclic type drug (serotonin-norepinephrine reuptake inhibiting ...Read more


Dr. Heidi Fowler
327 doctors shared insights

Endep (Definition)

Endep is a tertiary amine tricyclic which is a kind of tricyclic type drug (serotonin-norepinephrine reuptake inhibiting ...Read more