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Doctor insights on: Amitriptyline Metabolism

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Dr. Robert Kent
375 doctors shared insights

Elavil (Definition)

Elavil is a tertiary amine tricyclic which is a kind of tricyclic type drug (serotonin-norepinephrine reuptake inhibiting ...Read more


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Is 100mg of amitriptyline at bedtime too much?

Is 100mg of amitriptyline at bedtime too much?

No: Maintenance dose: is 150 to 300 mg per day orally in single or divided doses. Ask your doctor for more information. ...Read more

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Why prescribe titrate amitriptyline?

Why prescribe titrate amitriptyline?

Useful medication.: Amitriptyline can be helpful for many medical conditions, including migraines, insomnia, and depression. Side effects such as sleepiness, dry eyes, dry mouth, and constipation may occur. Side effects tend to be less if the medication is started at a low dose and gradually increased (titrated). ...Read more

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Is amitriptyline used to help sleep?

Is amitriptyline used to help sleep?

Sometimes: It can definitely aid in sleeping as it has significant drowsy side effects, but is usually prescribed to help with another condition like chronic fibromyalgia pain or other neurological pain like migraines sometimes with the added benefit of also helping you sleep. I'm sure there are some doctors out there who may prescribe it for the sole purpose of being a sleep aid. ...Read more

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How do you wing off 25mg amitriptyline?

How do you wing off 25mg amitriptyline?

Elavil (amitriptyline): can be weened over a period of a few weeks at this dose. Be sure to discuss this with your prescribing doctor. If you have it in tablet form you can break it into quarters and take away one quarter every 5 days. Consider replacing it with Pamelor (nortriptyline) which is less anticholinergic (dry mouth blurred vision etc) ...Read more

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Side effects from amitriptyline normal?

Ami side effects: Not unusual but can be circumvented by using the lowest effective dose - 2.5 - 10 mg. The dose is individualised based on med sensitiviy, family history of success (and the effective dosage), type of illness being treated, comorbid medical and emotional disease, anticipated side effects and potential/ currently existing interactions with other medications/supplements. ...Read more

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Is 25mg amitriptyline (elavil) safe to take?

Generally yes: Every patient is different, but generally speaking Amitriptyline 25mg is a very small, and safe, dose. For specific medication questions like this, however, you should talk to your doctor who knows you and your situation and not just rely on an internet answer. ...Read more

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Is rhodiola safe to take with amitriptyline?

Is rhodiola safe to take with amitriptyline?

Yes, it is: Rhodiola has been used safely with all antidepressant types except MAO inhibitors. Some studies have shown in vitro inhibition of cyp 3a4 and p-glycoprotein with rhodola http://tinyurl.Com/kkh3lhq but this hasn't caused difficulty when used by live patients. [van diermend, et al. J ethnopharmacology.2009 mar 18;122(2):397-401; a.] amitriptylene and rhodiola can be safely used together. ...Read more

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What are the effects of elavil (amitriptyline)?

What are the effects of elavil (amitriptyline)?

Elavil (amitriptyline): Is an antidepressant with sedating and drying effects, causing heart rate changes, dry mouth/eyes, constipation, depending on dose. It relieves depression, pain of neurogenic origin, headache and insomnia. ...Read more

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Does 20ml of endep (amitriptyline) help with pain?

Does 20ml of endep (amitriptyline) help with pain?

Type of pain?: Amitriptyline (Endep) is sometimes prescribed as an off-label treatment for certain types of pain. ...Read more

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Can i go off endep (amitriptyline) 10mg cold turkey?

Can i go off endep (amitriptyline) 10mg cold turkey?

Go see your doctor!: Australia's endep (amitriptyline) is sold in states as Elavil brand of Amitriptyline which is an early antidepressant w/anticholinergic properties, causing dry eyes & mouth, constipation, inability to urinate & confusion. Both http://www.Webmd.Com/drugs/drug-9159-endep (amitriptyline)+oral.Aspx?Drugid=9159&drugname=endep (amitriptyline)+oral & http://www.Drugs.Com/elavil.Html recommend tapering off under your doctor's supervision. ...Read more

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Why does elavil or amitriptyline make you gain weight?

Why does elavil or amitriptyline make you gain weight?

Antihistamine: The antihistamine effect of Amitriptyline is what stimulates appetite and ultimately leads to weight gain (also causes sleepiness). This class of tricyclic antidepressants (called tertiary amines) tends to have stronger antihistamine effect. The secondary amines like nortriptyline and desiprimine have less of the antihistamine effect. ...Read more

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What are the most common side effects of amitriptyline?

What are the most common side effects of amitriptyline?

Several: Sedation, dry mouth, dry eyes, blurry vision, sweating, appetite stimulation, constipation, and sometimes difficulty urinating. There can be complete urinary retention, with some. These side effects usually increase with dose, and some may dissipate with time. ...Read more

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Gained 20 pounds on elavil (amitriptyline). What to do?

Gained 20 pounds on elavil (amitriptyline). What to do?

D/C it, or diet: Elavil (amitriptyline) often causes wt gain. If it could be replaced with another antidepressant, then have your md d/c it and replace it - but you'll still need to do some exercise to help lose the wt. If you can't d/c the elavil, (amitriptyline) then you have to be aggressive about wt management: watching caloric intake and doing vigorous exercise. In worst cases, sometimes an appetite suppressant is used too. ...Read more

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What should I do if i feel addicted to amitriptyline now?

Dependence: Addictions imply you need more and more to get the same effects, and it doesn't work as before. You may be dependent on it if you don't feel good without it, but are you still better on it than before you started it. Then it is still helping. Relapse off the med is not a sign of addiction. Talk to your md if you feel you need it but have side effects. ...Read more

Dr. Heidi Fowler
322 doctors shared insights

Endep (Definition)

Endep is a tertiary amine tricyclic which is a kind of tricyclic type drug (serotonin-norepinephrine reuptake inhibiting ...Read more