Doctor insights on:
Amitriptyline And Nortriptyline
What is the difference between amitriptyline and nortriptyline? Is one more potent for certain things. Read that nortrip helps tinnitus for instance
Amitrip or Nortrip: Both drugs are in the same class called tricyclic antidepressants and have similar pharmacologic activity. Amitriptyline is converted by the body to nortriptyline. Amitriptyline tends to cause more sedation and nortriptyline is used when a more stimulatory side effect is desired. Amitriptyline is preferred when nightime drowsiness is desirable. Both drugs, in high doses can cause cardiac toxicity ...Read more
Classified as a tricyclic antidepressant, and considered of modest benefit these days due to significant anti-cholinergic side effects (drowsiness, dizziness, dryness of mouth, blurring, and perhaps effect on bladder). Confusion may occur in older folks. Had some value in migraine prevention at one point. Used rarely these days as ...Read more
In your option which migraine preventatives do you feel most effective. I've tried amitriptyline and nortriptyline but hallucinations were bad at nigt?
Which tcas is more potent for sciatica pain relief, amitriptyline(or nortriptyline), imipramine(or desipramine)?
TCA: Tca are classic for neuropathic pain - sciatica for example. Any of the ones u mentioned may be quite eefective - and cheap. They are not without side effects - dry mouth, constipation, sedation. Any of the ones u mentioned can be effective. I personally like amytryptilline - 10mg at night - as mentioned all will work. Additionally other meds such as lyrica, neurontin, Cymbalta are options. ...Read moreSee 1 more doctor answer
As a migraine sufferer. I have tried propranolol, amitriptyline, nortriptyline, toprimate and currently on sanomigrain.What would you suggest next.
Migraine treatment: Once a diagnosis of migraine has been made, effective management of migraine involves three specific strategies: 1) patient education, 2) nonpharmacological management (e.g. acupuncture), and 3) pharmacological (medical) management. See an orofacial pain or headache specialist for evaluation and professional management. ...Read moreSee 1 more doctor answer
If you are not getting the desired response on a low dose of Nortriptyline 20mg, could you switch to Amitriptyline as a straight swap?
Very rare: Amitriptyline and nortriptyline are tricyclic antidepressant, that have been associated with very rare but severe incidences of hepatotoxicity in patients. The cause is not known but likely is related to an allergic type reaction to a breakdown product. Chances are low that you will get this chemical hepatitis is low, but it seems prudent to check liver function tests while on the drug. ...Read more
Antihistamine: The antihistamine effect of Amitriptyline is what stimulates appetite and ultimately leads to weight gain (also causes sleepiness). This class of tricyclic antidepressants (called tertiary amines) tends to have stronger antihistamine effect. The secondary amines like nortriptyline and desiprimine have less of the antihistamine effect. ...Read moreSee 2 more doctor answers
Sometimes: It can definitely aid in sleeping as it has significant drowsy side effects, but is usually prescribed to help with another condition like chronic fibromyalgia pain or other neurological pain like migraines sometimes with the added benefit of also helping you sleep. I'm sure there are some doctors out there who may prescribe it for the sole purpose of being a sleep aid. ...Read moreSee 1 more doctor answer
The price on my amitriptyline went from $12 to $124.00 can you please tell me another med that is the closest to amitriptyline that I can get that wi?
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