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Doctor insights on: Amitriptyline Alcohol Interaction

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Can I drink alcohol while on amitriptyline?

Can I drink alcohol while on amitriptyline?

Not recommended: It is not recommended to drink alcohol when taking medications, including Elavil/amitriptyline. The liver is responsible for metabolizing both alcohol and medications, adding additional burden especially in those with medical problems. If taken as an anti-depressant, the goals of treatment with Elavil are being undone by drinking alcohol, which is by definition a nervous system depressant. ...Read more

Dr. Robert Kent
363 doctors shared insights

Elavil (Definition)

Elavil is a tertiary amine tricyclic which is a kind of tricyclic type drug (serotonin-norepinephrine reuptake inhibiting ...Read more


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Can i drink alcohol whilst being on amitriptyline?

Can i drink alcohol whilst being on amitriptyline?

Should not: Alcohol and Amitriptyline should not be used together. It may amplify Amitriptyline side effects and increase effects of alcohol such as decreased coordination and increased drowsiness. ...Read more

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I am on a low dose of tramadol. 50-100mg per day. Is it still safe to have alcohol ? Just stopped taking amitriptyline last week. 10mg per day.

I am on a low dose of tramadol. 50-100mg per day. Is it still safe to have alcohol ? Just stopped taking amitriptyline last week. 10mg per day.

Not recommended: Tramadol and alcohol are depressant of the central nervous system. Mixing tramadol with alcohol could lead to drowsiness to severe depression of brain activity, coma, and ultimately death. Tramadol has a prolonged half-life about 7 hours. It is still in your system for at least 10 hours. Is not recommended. ...Read more

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Does alcohol cause insomnia?Im on amitryptyline and take a glass wine and next day i couldnt sleep, can't relax its feels like tremor when try to sleep

Alcohol insomnia: Yes alcohol can cause insomnia, especially as it wears off. You can get a rebound effect. Also some people get paradoxical reactions. So where a substance can relax many people, there are some people who become more anxious. And you are taking prescribed medication that could be interacting. You should speak to your prescribing doctor who will probably advise you not to drink alcohol. ...Read more

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I had 1 beer several hours ago and take 30mg amytriptaline at night before bed for anxiety. I read you're not supposed to drink alcohol will I be ok?

I had 1 beer several hours ago and take 30mg amytriptaline at night before bed for anxiety. I read you're not supposed to drink alcohol will I be ok?

Please be careful...: You should be ok from a physical standpoint - one standard drink takes about 2 hours to metabolize; However, it is strongly recommended to avoid alcohol while taking amytriptyline, as the combination can increase drowsiness (putting you or others at risk for injury) and alcohol can reduce the effectiveness of the medication. If necessary, please be sure to get a sober ride from someone you trust. ...Read more

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Would there be any drug interaction by taking meloxacam and amitriptyline?

Would there be any drug interaction by taking meloxacam  and amitriptyline?

Drug interactions: No drug interactions are listed between Meloxicam & amitriptyline. Remember, however, that Elavil (amitriptyline) alone can have side effects such as sedation, constipation, difficulty urinating, blurred vision. Never mix Elavil with other sedating drugs, especially alcohol. ...Read more

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For severe neuropathy I'm on Cymbalta (duloxetine) 60mg daily. About to add Amitriptyline 50mg daily. Any interactions? Concerned about mood alteration effects.

For severe neuropathy I'm on Cymbalta (duloxetine) 60mg daily. About to add Amitriptyline 50mg daily. Any interactions?  Concerned about mood alteration effects.

Serotonin drugs: taking both medications may increase your risk for serotonin syndrome. Mirtazapine may be a better adjunct to duloxetine. Duloxetine could be raised to a higher dose first. If additional treatment is needed, consider mirtazapine augmentation ...Read more

Dr. Heidi Fowler
306 doctors shared insights

Endep (Definition)

Endep is a tertiary amine tricyclic which is a kind of tricyclic type drug (serotonin-norepinephrine reuptake inhibiting ...Read more