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Doctor insights on: Ambien Vs Klonopin

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Klonopin and Ambien, (zolpidem) are they ok to take?

Klonopin and Ambien, (zolpidem) are they ok to take?

Not really...: Probably not a good idea to mix these drugs together. An interaction effect with an increase in anxiety, insomnia, memory disturbance, and possible excessive sedation. Talk to your doctor about possible alteration of the dose and type of medicine. ...Read more

Dr. Donald Jacobson
841 Doctors shared insights

Clonazepam (Definition)

Klonopin (clonazepam) belongs to a class of medications called benzodiazepines. They are also referred to as sedative-hypnotics & anxiolytics. These medications are used for a variety of indications to include anxiety, insomnia, muscle spasm, seizure, & alcohol withdrawal. All benzodiazepines including Clonazepam are potentially habit forming. Alcohol should be ...Read more


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How to keep ambien (zolpidem) working? Only med that has ever worked for me. Will it have cross tolerance with other Meds like klonopin? I know it's short term but the belsomra rx I was given doesn't look promising at all.

How to keep ambien (zolpidem) working? Only med that has ever worked for me. Will it have cross tolerance with other Meds like klonopin? I know it's short term but the belsomra rx I was given doesn't look promising at all.

Not sure there is a: Way. The use of ambien (zolpidem) may not continue if you develop tolerance. You might ask your doc if the dose is right. You have not mentioned your dose, it can be taken up to 10 mg at bedtime. There is not much cross tolerance with klonopin but actually may be additive effects. Would not suggest taking them together if not needed. Try the belsomra at the max dose prior to giving up. Ask your doc ...Read more

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I took 4 ambien, (zolpidem) 3 klonopin and 3 zestoretic just so I could sleep, was it safe to mix those medications?

I took 4 ambien, (zolpidem) 3 klonopin and 3 zestoretic just so I could sleep, was it safe to mix those medications?

Not safe: Zestoretic is not for sleep- Klonopin and Ambien (zolpidem) is for sleep- it is not safe to mix these two medications particularly high dosages. ...Read more

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Dr just added 25 mg of trazadone for sleep...does this make sense rather than add ambien (zolpidem) or go up on klonopin?

Dr just added 25 mg of trazadone for sleep...does this make sense rather than add ambien (zolpidem) or go up on klonopin?

Yes: Trazodone is a an antidepressant which is often added at bedtime for it's sedating effect to help insomnia. It is non-addicting, therefore preferred for longer term use. The 25 mg dose is low and reasonable. Your mood may also improve. Hope this helps. ...Read more

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Is it dangerous to take 2 mg of klonopin, 10 mg of ambien (zolpidem) and 50 mg of trazodone all within a half hour in order to sleep? I'm a 140 lb woman.

Is it dangerous to take 2 mg of klonopin, 10 mg of ambien (zolpidem) and 50 mg of trazodone all within a half hour in order to sleep? I'm a 140 lb woman.

Depends: Usually a doctor will not start with all three of those medications at that dosage. If the medication is being titrated up such dosages might be prescribed. SOmetimes Trazadone will be an even higher dosage.
Hopefully you and your doctor will try to figure out why you are having trouble sleeping and psychotherapy might be considered. ...Read more

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150 mg Trazodone, 1 mg klonopin. And 10 mg ambien (zolpidem). Ambien (zolpidem) doesn't work for me by itself been on klonopin for years. Trazodone was great in the past. Any thoughts.? Sounds like a major hangover to me.

Sleep study: This is a potentially very dangerous combination of drugs affecting the brain. Have you had a sleep study done to find out the cause? Depression or anxiety is another cause for insomnia. I would certainly explore both avenues instead of continuing on this medication cocktail. Don't delay any further. ...Read more

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I am prescribed Adderall regularly for many years now. Is it safe to take 1.5mg of klonopin and 10mg of Ambien (zolpidem) to help me sleep?

I am prescribed Adderall regularly for many years now. Is it safe to take 1.5mg of klonopin and 10mg of Ambien (zolpidem) to help me sleep?

Don't do it!: Taking way too many medications, which interact with each other, makes no sense. Talk to your doctor about other options ...Read more

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Why would my psych doc prescribe klonopin and ambien (zolpidem) together for chronic insomnia? Doesn't that make tolerance go up faster for meds?

Why would my psych doc prescribe klonopin and ambien (zolpidem) together for chronic insomnia? Doesn't that make tolerance go up faster for meds?

Chronic Insomnia: I understand your concern.
Both Klonopin and Ambien (zolpidem) can be habit forming, and you can develop tolerance.
Using Klonopin with Ambien (zolpidem) may increase dizziness and difficulty concentrating. Some people may experience impairment in thinking and judgment
Discuss with Psychiatrist Diagnosis of Chronic insomnia, Medication benefits and side effects ; Therapy for stress for stress in your life, Relaxation. ...Read more

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My doctor put me on 1 mg klonopin plus 10 mg ambien for insomnia and anxiety to be taken together. I feel awful when I take together and doesn't really work that great? Wouldn't it be better to just increase the ambien and stop the klonopin?

My doctor put me on 1 mg klonopin plus 10 mg ambien for insomnia and anxiety to be taken together. I feel awful when I take together and doesn't really work that great? Wouldn't it be better to just increase the ambien and stop the klonopin?

Bad combo: Combining these medications should be avoided, since they are both sedatives/hypnotics. Also, long-term use of amben is not recommended. It would actually be better to treat your underlying anxiety to try and resolve your sleep issues, since long-term ambien (zolpidem) use leads to rebound insomnia and addiction. ...Read more

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And I hate being on Prozac klonopin ambien (zolpidem) and add medicine and lots others and I would rather smoke marihuana because it helps all of these problems better for me. But I get drug tested.?

And I hate being on Prozac klonopin ambien (zolpidem) and add medicine and lots others and I would rather smoke marihuana because it helps all of these problems better for me. But I get drug tested.?

Illegal Most Places: Marijuana is illegal in must states still so must be avoided. I agree you need healthier alternative to all the medication. It has been shown that physical exercise can be very helpful. CBT (cognitive behavioral therapy) is an excellent talk therapy that can be very helpful. ...Read more

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I take Ambien (zolpidem) 10mg PO HS. In the past I have tried Ativan 2mg, Klonopin 2mg and Restoril 30mg. They All make me groggy! Would Halcion 0.25mg be better?

Sleeping Pill: Let me see if I understand your question correctly. You are taking a sleeping pill and you are concerned that they make you groggy. That is what they are designed to do! If you are groggy when you wake up then you are taking too high of a dose of the medication. All of the doses you have mentioned are the high range of the medication. Halcion is much longer acting. Ask your doc about 1/2 Ambien (zolpidem) ...Read more

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I have just been changed from Oxycodone 180mg QD to Methadone 50mg QD (for pain) I also take Klonopin, Soma, Ambien, (zolpidem) Lexapro & Tofranill, is this Dang?

I have just been changed from Oxycodone 180mg QD to Methadone 50mg QD (for pain) I also take Klonopin, Soma, Ambien, (zolpidem) Lexapro & Tofranill, is this Dang?

Always be careful: methadone is a very effective pain medication with great pain control with less psychological overtunes You are on a lot of medication and some overlap like ambien (zolpidem) and klonopin, Soma and methadone and Lexapro and tofranil Also tofranil mixes with the methadone Make sure you are being followed closely ...Read more

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What to do if I take norvasc, klonopin, accolate, Ambien (zolpidem) and remeron. And is there a safe pain killer to take?

What to do if I take norvasc, klonopin, accolate, Ambien (zolpidem) and remeron. And is there a safe pain killer to take?

Depends.: What type of pain are you trying to treat? If this is due to Arthritis, any NSAID like Naprosyn, Celebrex or Ibuprofen can help. Tylenol (acetaminophen) may also be helpful. These medications can be used for headaches, toothaches or muscles aches. Post-surgical pains may need a stronger pain medication initially such as Hydrocodone or at the discretion of the doctor. ...Read more

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I'm having lots of itching and sneezing. Want to try benadryl (diphenhydramine). Is it ok to take with klonopin, seroquel and ambien?

I'm having lots of itching and sneezing. Want to try benadryl (diphenhydramine). Is it ok to take with klonopin, seroquel and ambien?

Lots of interactions: There are lots of interaction between all 3 medicines you are taking which in combination cause brain depression and psychomotor impairment. Adding Benadryl (diphenhydramine) will further aggravate side effects. Why do you have to take first three drugs in the first place. Look for the cause for depression anxiety or whatever reason you are taking mess. Visit us at www. Ehacstl. Com to see how you can be helped ...Read more

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Insomnia causing migraines to act up I got botox injections yesterday, is it safe to combine Ambien (zolpidem) xanex and klonopin to try and get good night sleep?

Insomnia causing migraines to act up I got botox injections yesterday, is it safe to combine Ambien (zolpidem) xanex and klonopin to try and get good night sleep?

Bad idea: Mixing these medications increase sedation and drowsiness. Combination of these 3 drugs increases risk of CNS (central nervous system) depression, possible breathing crisis and death. See sleep disorders specialist (neurologist) for evaluation, diagnosis and proper treatment. Be safe and call your doctor. ...Read more

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Can I use plexus slim with Vyvanse Lexapro Suboxone klonopin Ambien (zolpidem) hctz atenolol levothyroxine & atorvastatin? Thank you.

Yes you can but: You can as there is no interaction but since you do have several medical conditions and taking all those meds I will advice to get approval of your doctor if you go on any very low calorie diet. ...Read more

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Is it ok to take ambien (zolpidem) and clonazepam at the same time?

No.: You haven’t said what your doses are or what time. If you take them both at bedtime, then you increase the risk of behavioral and cognitive adverse effects, which zolpidem is notorious for. (Above all, don’t add alcohol.) And there can be a first time, when problems haven’t happened previously. Instead, discuss with your prescriber an alternative approach to your sleep problem. ...Read more

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Is Taking clonazepam 0.5mg & ambien (zolpidem) 20mg between 8pm-10pm ok?

Cloneazepam ambien (zolpidem): Wow you are taking two medications that work on the Benzo receptor. Your Ambien (zolpidem) is far too high and current recommendation is that ambien (zolpidem) should not exceed 6.25mg and only to be used short duration. So I guess its not okay to use both at the same time. ...Read more

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Is clonazepam better than Ambien (zolpidem) for sleep in terms of side effects?

Is clonazepam better than Ambien (zolpidem) for sleep in terms of side effects?

Understand: They have the same exact mechanism of action. Ambient better for initiation, Clonazepam better for maintaining. Both will result in dependence and rebound insomnia with prolonged use. Also there will be increased irritability 12-24 hrs later. ...Read more

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My husband and I want to try to conceive, how long before trying should I stop taking my meds? Address XR, Ambien, (zolpidem) Amitriptyline and Clonipin?

Regular periods: So long as you have regular periods and there have been no recent changes in your medication regimen- I'd say your chances of conception are the same taking as well as not taking those medications you've mentioned. ...Read more

Dr. Donald Jacobson
827 Doctors shared insights

Klonopin (Definition)

Klonopin is a long-acting benzodiazepine which is a kind of sleep-inducing drug (anti-anxiety drug, psychiatric drug) and a blood pressure drug which is a ...Read more


Ambien (Definition)

Zolpidem is a sleep-inducer which is a kind of ...Read more