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Doctor insights on: Amaryl Second Generation Sulfonylurea

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Using amaryl (glimepiride) 3 before breakfast. Glocophage500+ glocovans 500?

Using amaryl (glimepiride) 3 before breakfast. Glocophage500+ glocovans 500?

Sulfonylurea.: That seems like a lot of sulfonylurea type medication - Glimepiride and Glyburide. The reason why that's important is that they can cause hypoglycemia (low blood sugar) which can be dangerous. I'd like to see you on more Metformin and less sulfonylurea to reduce your risk of hypoglycemia. ...Read more

Dr. Hamid Sajjadi
72 doctors shared insights

Glimepiride (Definition)

Treats type 2 diabetes. Used together with a proper diet and exercise to help control high blood sugar. This ...Read more


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Are Glimepiride & glipizide the same drug?

Are Glimepiride & glipizide the same drug?

No, but same class: Both are 2nd generation sulfonylurea drugs for treatment of Type 2 Diabetes. According to a review by the Utah gov't, they conclude: "Overall ranges of HbA1c reduction seen w/glimepiride, glipizide & glyburide treatment in current literature are similar & choice of antidiabetes therapy should be based on individual patient characteristics, including: efficacy, cost, (see below) ...Read more

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Difference between first and second generation antihistamines? Why are 1st generation considered nonsedating?

Difference between first and second generation antihistamines? Why are 1st generation considered nonsedating?

Sedation: 1st generation are sedating because many people, up to 40%, get sleepy when taking them. 2nd generation antihistamines are chemically modified and are less likely to cause sedation. The generics of the less sedating are cetirizine, fexafenadine, and loratidine. They cause sedation in some people, up to 11%, but much less than the older drugs. ...Read more

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Is the glipizide more effective than glyburide and januvia (sitagliptin)?

Is the glipizide more effective than glyburide and januvia (sitagliptin)?

No: Depending on how high your initial sugar levels are all 3 will lower the a1c about 0.3-1.0%. Glyburide is a poor choice for people with kidney problems and januvia (sitagliptin) is expensive. Most guidelines suggest beginning with metformin. Talk to your doctor. ...Read more

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Which is better glucotrol (glipizide) or glimepiride?

Neither is my choice: Hi. I'm not a fan of sulfonylurea drugs (the class they're both in) and haven't written for any in years. Nevertheless, between the two, I'd prefer glimepiride by a slight margin. ...Read more

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Iam diabetic since 2003 and stoped ameryl in 2007 to start lantus (insulin glargine) insulin then novo mix 30 in 2009 with metforal 850 what new pills now more effective?

There are a: variety of different medication regimens that can be effective, but you need to couple them to diet, exercise and weight loss. The most effective metformin dose is 1000 mg twice/day. Multiple doses of rapid acting Insulin before meals and a basal Insulin such as glargine at bedtime is better than mixed insulin. Other oral therapies and injectable glp-1 agonists need to be discussed with your docto ...Read more

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Will i ever have a natural erection again? Taking androgen 4 pumps/d. Have dm ii, ex opioid addict, taking suboxone, Effexor 150mg/d, glucovance (glyburide and metformin)

Will i ever have a natural erection again?  Taking androgen 4 pumps/d.  Have dm ii,  ex opioid addict, taking suboxone, Effexor 150mg/d, glucovance (glyburide and metformin)

ED: Very difficult to say , it depends on how well your diabetes is controlled , how long you been on the androgen and it may or may not help. I hope you can to speak with your doctor at length about this. Good luck. ...Read more

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We think we just put novolog in the levemir (insulin detemir) bottle we have no more levemir (insulin detemir).... Is the levemir (insulin detemir) ruined it was 10 units..

We think we just put novolog in the levemir (insulin detemir) bottle we have no more levemir (insulin detemir).... Is the levemir (insulin detemir) ruined it was 10 units..

Novolog is rapid: Acting ; is used to cover sugars that are elevated pre meals, when you mix the two you could get reaction- do not use the mixture you now have. ...Read more

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Today my doctor prescribe a infertility medicns i.E tinidazole , l_methylfolate, chymoral forte, third generation cephalosporin.Is that good medicn?

Today my doctor prescribe a infertility medicns i.E tinidazole , l_methylfolate, chymoral forte, third generation cephalosporin.Is that good  medicn?

Not fertility meds: The medications you are describing are several antibiotics, vitamins and enzymes. None of these are infertility medications. If you are not sure why he/she prescribed them, you should ask your doctor what they are for. ...Read more

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How do glimepiride, metformine, lantus (insulin glargine) and byetta work together?

How do glimepiride, metformine, lantus (insulin glargine) and byetta work together?

Diabetes: The four medications work in 4 different mechanisms with the end goal of keeping blood sugar under control. Would suggest taking Glimepiride in mornings, metformin & Byetta before meals & Lantus (insulin glargine) at bedtime. Goal fasting blood sugar of 100 & hba1c of 6.5 good luck. ...Read more

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Type II diabetic, blood insulin last test (NOT glucose)=29.5 On lantus (insulin glargine) 62 units, humalog 17 units. Am I still producing endogenous insulin?

Type II diabetic, blood insulin last test (NOT glucose)=29.5 On lantus (insulin glargine) 62 units, humalog 17 units. Am I still producing endogenous insulin?

Need C-peptide test: Since exogenous (injected) insulin will show on a blood test, C-peptide should be measured to assess for endogenous insulin. Proinsulin is made by the pancreas, then cleaved into C-peptide & insulin. Exogenous insulin has no C-peptide. ...Read more

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Whats the difference between a first generation antihistamine like chlorpheniramine and second generation antihistamines like allegra (fexofenadine)?

Whats the difference between a first generation antihistamine like chlorpheniramine and second generation antihistamines like allegra (fexofenadine)?

1st and second: First generation antihistamines are sedating and short acting and have usually other properties such as anticholinergic or drying properties. Second generation antihistamines are long aciting, usually dosed once a day, and are less or non sedating and selective antihistamines with less active properties on other receptors. ...Read more

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Hello. Is omega XL safe for diabetics taking insulin metformin glipizide Lipitor (atorvastatin) diazid tricor & bp meds, spiriva advair. ?

Hello. Is omega XL safe for diabetics taking insulin metformin glipizide Lipitor (atorvastatin) diazid tricor & bp meds, spiriva  advair. ?

Exercise caution: you are already on multiple medications, some possibly interact together, you don't want to add more unless really needed, even if it is a supplement, fatty acids in omega fish oil might increase lipids in your system, this is not against any drug but rather for your own safety, please revise all your meds with your doctor on regular basis, good luck ...Read more

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Husband recently started taking humalog (insulin lispro). Is this the best insulin ?

Husband recently started taking humalog (insulin lispro). Is this the best insulin ?

It's really good.: Humalog (insulin lispro) is a brand of rapid-acting Insulin produced by eli lilly & co. Here in the usa. It is given at meals (or in an Insulin pump), to provide quick-onset action to control blood sugars at meals. There are a couple of other brands of rapid-acting Insulin on the market (novolog, apidra), but they all have about the same action. ...Read more

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Dlabetic&hypertensive, bmi31 , on amarylm2 tab 2x3, novonorm2 1x3 and lantus (insulin glargine) insulin +3o min excercise. ....A1c 9.7 please help!

Dlabetic&hypertensive, bmi31 , on amarylm2 tab 2x3, novonorm2 1x3 and lantus (insulin glargine) insulin +3o min excercise.    ....A1c 9.7     please help!

Your endocrinologist: Needs to adjust/ increase the dose of your medicine esp Insulin to attain good control of your sugar reflected in your a1c (ideally in the 6 or 7 range). A good diet & exercise regimen would help as well. Increase your water intake to maintain good kidney function. Annual or periodic ekg is a must have your annual eye check , lipid and kidney function monitored closely .Take care & god bless u! ...Read more

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Dlabetic&hypertensive, bmi31 , on amarylm2 tab 2x3, novonorm2 1x3 and lantus (insulin glargine) insulin +3o min excercise. ....A1c 9.7 please help!

Dlabetic&hypertensive, bmi31 , on amarylm2 tab 2x3, novonorm2 1x3 and lantus (insulin glargine) insulin +3o min excercise.    ....A1c 9.7     please help!

High Hb a1c: You need to go to an endocrinologist (e) to see if your diet needs to be changed. The regimen of medicines you take to control your diabetes is clearly not working and this may be due to inadequate dosing or ingesting too many carbohydrates. If you reduce your bmi, there is a chance to control your glucose better. Get your glucose under control to avoid harmful complications of diabetes, see an e. ...Read more

Dr. Hirenkumar Italia
58 doctors shared insights

Amaryl (Definition)

Amaryl is a second generation sulfonylurea which is a kind of diabetes-related drug ...Read more