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Doctor insights on: Alzheimers And Depakote

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Fleisher et al (Neurology, 2011) found Depakote accelerated brain atrophy in Alzheimer's. Should those with family history of Alz. avoid Depakote?

Fleisher et al (Neurology, 2011) found Depakote accelerated brain atrophy in Alzheimer's. Should those with family history of Alz. avoid Depakote?

Not so simple: Your statement is taken out of context. First, Depakote does not cause alzheimer's or make it worse, and may help the symptom of agitation. Second, this dementia causes accelerated brain atrophy as part of the process. Third, a family history is not necessarily a direct link to alzheimer's, as this is far more complex. Many pts where Depakote is not appropriate, but this isn't one. ...Read more

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Dr. Jeffrey Cohen
237 doctors shared insights

Divalproex (Definition)

Divalproex, is a seizure medicine, the generic name is valporic acid, it has been in the market as an antiseizure medicine for long time, it is a good medicine, helps to control almost all types of common seizures, partial, generalized, absence, myoclonic, atonic, ..Etc.It can be used as a mood stabilizer in psychiatric patients. It has adverse effects on the liver, ...Read more


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What is probable alzheimers?

What is probable alzheimers?

Consistent picture: Gold standard might implicate a pet scan showing classical metabolic changes in appropriate brain areas. Spinal fluid studies would confirm the disorder. The clinical picture develops without other explanation. Mental status testing reveals progressive declines without reversal. ...Read more

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What are symptoms of alzheimers?

What are symptoms of alzheimers?

10 warning signs: See this link for the 10 warning signs of alzheimer's disease. Alzheimer's: http://www.Alz.Org/alzheimers_disease_know_the_10_signs.Asp. ...Read more

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What is the cause of alzheimers?

What is the cause of alzheimers?

Many causes: Try Alzheimer's.org - they have nice details. Abnormal levels of a bad protein called AB42 in oligomer form along with hyperphosphoryated tau. TDP-43 and abnormal progranulin levels and others may also play a role in some cases. Inflammation is pivotal. Genetics defects can be in coding for an enzyme that forms AB42, or one that helps clear it from the brain. ...Read more

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Is there benefit from doing crosswords for alzheimers?

Is there benefit from doing crosswords for alzheimers?

Alzheimer's: Depends on the stage of dementia. There is no cure and the further someone progresses, the less it will help. ...Read more

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What is pre-alzheimer's?

What is pre-alzheimer's?

Same as MCI: It is working in progress. Mild cognitve impairment, pre alzheimer's, syndromal alzheimer's are very similar but it is not clearly defined. Dementia is very broad term and alzheimer's disease is the most common form of dementia. ...Read more

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What is Alzheimer's disease?

Common dementia: Alzheimer's disease is the most common type of dementia. Memory problems, word finding problems, word substitutions errors, getting lost in places that are familiar are often early symptoms. Also forgetting how to use tools that you used to know how to use. Finally, trouble evaluating info and following plans happen later. ...Read more

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What is alzheimer's disease?

Dementia: Alzheimer's is a specific form of dementia which includes severe short term and intermediate memory disturbance. There is some evidence it is genetic. There are very specific changes I the brain, but these are not easily identified by current brain scans ...Read more

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What is alzheimer's disease?

What is alzheimer's disease?

A form of dementia: Alzheimer' s disease is one type of dementia, conditions marked by of decline in cognitive status because of brain changes which lead to problems functioning. Its exact cause is not known but the greatest risk factor is old age and some forms that run in families. Sometimes other reversible conditions such as depression or low sodium can mimic symptoms so a careful diagnosis is the first step ...Read more

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What are alzheimer's stages?

Contact the: Alzheimer's foundation, or the judy fund in california. They have all the latest information. ...Read more

Depakote (Definition)

Depakote is the brand name for a medication known as valproic acid. It is most commonly used to treat seizures, though it can also be used as a mood stabilizer in certain psychiatric disorders. It is used to treat multiple seizure types and can be used alone or with other seizure medications if needed. Common side effects include nausea, dizziness, ...Read more