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Doctor insights on: Alternatives To Octreotide

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Dr. Mark Ingerman
23 Doctors shared insights

Sandostatin (Definition)

Sandostatin ...Read more


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How does octreotide work?

How does octreotide work?

Cyclic octapeptide: Works by counter-acting growth hormone, glucagon, and insulin. It mimics a natural hormone called somatostatin. Because of how it works, it is used for the management of acromegaly, carcinoid syndrome, and it can be used to treat diarrhea associated with certain tumors.

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What is sandostatin (octreotide) lar?

Sandostatin (octreotide) LAR: Is long-acting suspension used after the initial sandostatin (octreotide) injection was shown effective.

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What is the drug octreotide used for?

What is the drug octreotide used for?

Diarrhea, carcinoid: It is used for refractory diarrhea when other medications do not work, and for treatment of carcinoid tumors and associated symptoms.

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Which organs does octreotide vasoconstrict exactly?

Which organs does octreotide vasoconstrict exactly?

Intestinal vessels: The main use of octreotide is to control abnormal hormone production by various endocrine tumors. However, it can also be used in people with gastrointestinal bleeding, including esophageal varices to slow bleeding. It does this by constricting blood flow in intestinal (splanchnic) vessels. There is also research looking at treating diabetic retinopathy by constricting bleeding vessels in the eye.

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How does sandostatin (octreotide) react with medications?

Interactions: Octreotide is a complicated agent. Interactions are possible with various different drug classes. Can check online vs the drugs you take or check with your pharmacist.

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What are the effects of the chemo drug octreotide?

What are the effects of the chemo drug octreotide?

This not a true chem: It is a form of somatostatin, which is used to treat symptoms from carcinoid syndrome such as severe diarrhea, itch severe flushing. It has many other uses outside of oncology. It also is used for scaning for spread of carcinoid and other tumors associated with a neuroendocrine function it can affect the thyroid, glucose control, heart rate as side effects.

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What is an octreotide scan?

What is an octreotide scan?

Type of tumor scan: Used to find carcinoid and certain other tumors. Octreotide (similar to somatostatin) is labelled with a radioactive tracer and injected. It binds to carcinoid tumor cells and certain other tumors with somatostatin receptors. A nuclear medicine camera can image the location and distribution of the tumor cells.

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Please help! What is the chemo drug octreotide?

Please help! What is the chemo drug octreotide?

Octreotide: Octreotide mimics natural somatostatin pharmacologically, though it is a more potent inhibitor of growth hormone, glucagon, and Insulin than the natural hormone. Fda has approved octreotide acetate, as an injectable depot formulation for the treatment of growth hormone producing tumors, certain pituitary tumors, vipomas, and carcinoid syndrome.

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How do I calculate the daily dose of octreotide?

How do I calculate the daily dose of octreotide?

Let me help: Usual adult dose for carcinoid tumor initial dose: 100 to 200 mcg subcutaneously 3 times a day. Maintenance dose: 50 to 300 mcg/day. Maximum dose: 1, 500 mcg/day.

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What is the chemo drug octreotide? How does it work?

What is the chemo drug octreotide? How does it work?

Somtatostatin analog: This mimics somatostatin. A peptide hormone secreted by the pancreas. its job is to antagonize other pancreatic hormones. So think of it as a synthetic somatostatin. It is given as injections in the skin and used to treat different kinds of endocrine tumors. In oncology it is known for its use against carcinoid (serotonin secreting tumors) and chemotherapy induced diarrhea.

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How can sandostatin (octreotide) react with hypertensive medications?

No issues here: I do not believe there is any interaction between the tow. You should be able to take both safely.

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How risky or unrisky is it to give sandostatin (octreotide) lar after only 1 subcutaneous 'test dose'?

Sandostatin (octreotide): It is best to work the dose up slowly to avoid some rather unpleasant symptoms/side effects.

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How healthy or unsafe is it to give sandostatin (octreotide) lar after only 1 subcutaneous 'test dose'?

How healthy or unsafe is it to give sandostatin (octreotide) lar after only 1 subcutaneous 'test dose'?

Should be fine: If you tolerated the test dose, you should be OK going straight to the LAR. Low risk of adverse events.

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How does octreotide help fight cancer?

How does octreotide help fight cancer?

Octreotide analog: Is used in treating carcinoid tumors, and as a nuclear medicine scan, to define location of such tumors and potential metastasis. It is of no use in other cancers.

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Pls describe an allergic reaction to a sandostatin (octreotide) shot...

Pls describe an allergic reaction to a sandostatin (octreotide) shot...

Sandostatin (octreotide) Effects.: Side effects that you should report to your doctor or health care professional as soon as possible: allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue, changes in blood sugar, changes in heart rate, severe stomach pain. Diarrhea, nausea, vomiting, hair loss.

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Can you tell me about lar on essentially the 1st day of sandostatin (octreotide) treatment?

Can you tell me about lar on essentially the 1st day of sandostatin (octreotide) treatment?

There's a lot to it: B"sd an endocrinologist is always interested in sandostatin a long acting brand orf octreotide: is an octapeptide that mimics natural somatostatin pharmacologically, though it is a more potent inhibitor of growth hormone, glucagon, and insulin than the natural hormone". It has a number of other actions and classicaly a medical rx of acromegally. Certainly, glad to discuss in more detail.

Dr. Bernard King
255 Doctors shared insights

Octreotide (Definition)

Octreotide ...Read more