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Doctor insights on: Alternatives To Octreotide

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Dr. Marvin Ott
23 Doctors shared insights

Sandostatin (Definition)

Sandostatin ...Read more


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How does octreotide work?

How does octreotide work?

Cyclic octapeptide: Works by counter-acting growth hormone, glucagon, and insulin. It mimics a natural hormone called somatostatin. Because of how it works, it is used for the management of acromegaly, carcinoid syndrome, and it can be used to treat diarrhea associated with certain tumors. ...Read more

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What is sandostatin (octreotide) lar?

Sandostatin (octreotide) LAR: Is long-acting suspension used after the initial sandostatin (octreotide) injection was shown effective. ...Read more

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What is the drug octreotide used for?

What is the drug octreotide used for?

Diarrhea, carcinoid: It is used for refractory diarrhea when other medications do not work, and for treatment of carcinoid tumors and associated symptoms. ...Read more

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Which organs does octreotide vasoconstrict exactly?

Which organs does octreotide vasoconstrict exactly?

Intestinal vessels: The main use of octreotide is to control abnormal hormone production by various endocrine tumors. However, it can also be used in people with gastrointestinal bleeding, including esophageal varices to slow bleeding. It does this by constricting blood flow in intestinal (splanchnic) vessels. There is also research looking at treating diabetic retinopathy by constricting bleeding vessels in the eye. ...Read more

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How does sandostatin (octreotide) react with medications?

Interactions: Octreotide is a complicated agent. Interactions are possible with various different drug classes. Can check online vs the drugs you take or check with your pharmacist. ...Read more

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What are the effects of the chemo drug octreotide?

What are the effects of the chemo drug octreotide?

This not a true chem: It is a form of somatostatin, which is used to treat symptoms from carcinoid syndrome such as severe diarrhea, itch severe flushing.
It has many other uses outside of oncology. It also is used for scaning for spread of carcinoid and other tumors associated with a neuroendocrine function
it can affect the thyroid, glucose control, heart rate as side effects. ...Read more

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What is an octreotide scan?

What is an octreotide scan?

Type of tumor scan: Used to find carcinoid and certain other tumors. Octreotide (similar to somatostatin) is labelled with a radioactive tracer and injected. It binds to carcinoid tumor cells and certain other tumors with somatostatin receptors. A nuclear medicine camera can image the location and distribution of the tumor cells. ...Read more

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Please help! What is the chemo drug octreotide?

Please help! What is the chemo drug octreotide?

Octreotide: Octreotide mimics natural somatostatin pharmacologically, though it is a more potent inhibitor of growth hormone, glucagon, and Insulin than the natural hormone. Fda has approved octreotide acetate, as an injectable depot formulation for the treatment of growth hormone producing tumors, certain pituitary tumors, vipomas, and carcinoid syndrome. ...Read more

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How do I calculate the daily dose of octreotide?

How do I calculate the daily dose of octreotide?

Let me help: Usual adult dose for carcinoid tumor

initial dose: 100 to 200 mcg subcutaneously 3 times a day.
Maintenance dose: 50 to 300 mcg/day.
Maximum dose: 1, 500 mcg/day. ...Read more

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What is the chemo drug octreotide? How does it work?

What is the chemo drug octreotide? How does it work?

Somtatostatin analog: This mimics somatostatin. A peptide hormone secreted by the pancreas. Its job is to antagonize other pancreatic hormones. So think of it as a synthetic somatostatin.
It is given as injections in the skin and used to treat different kinds of endocrine tumors.
In oncology it is known for its use against carcinoid (serotonin secreting tumors) and chemotherapy induced diarrhea. ...Read more

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How can sandostatin (octreotide) react with hypertensive medications?

No issues here: I do not believe there is any interaction between the tow. You should be able to take both safely. ...Read more

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How risky or unrisky is it to give sandostatin (octreotide) lar after only 1 subcutaneous 'test dose'?

Sandostatin (octreotide): It is best to work the dose up slowly to avoid some rather unpleasant symptoms/side effects. ...Read more

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How does octreotide help fight cancer?

How does octreotide help fight cancer?

Octreotide analog: Is used in treating carcinoid tumors, and as a nuclear medicine scan, to define location of such tumors and potential metastasis. It is of no use in other cancers. ...Read more

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Pls describe an allergic reaction to a sandostatin (octreotide) shot...

Pls describe an allergic reaction to a sandostatin (octreotide) shot...

Sandostatin (octreotide) Effects.: Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue,
changes in blood sugar,
changes in heart rate,
severe stomach pain.
Diarrhea, nausea, vomiting, hair loss. ...Read more

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Can you tell me about lar on essentially the 1st day of sandostatin (octreotide) treatment?

Can you tell me about lar on essentially the 1st day of sandostatin (octreotide) treatment?

There's a lot to it: B"sd an endocrinologist is always interested in sandostatin a long acting brand orf octreotide:
is an octapeptide that mimics natural somatostatin pharmacologically, though it is a more potent inhibitor of growth hormone, glucagon, and insulin than the natural hormone". It has a number of other actions and classicaly a medical rx of acromegally. Certainly, glad to discuss in more detail. ...Read more

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What is octreotide; is it related to growth hormone?

What is octreotide; is it related to growth hormone?

Octreotide is a …: Synthetic version of somatostatin (growth-hormone-inhibiting hormone) that is more potent inhibitor of growth hormone, glucagon, & Insulin than the natural hormone. It is approved for treating growth hormone disorders like acromegaly & gigantism & also for treating certain tumor-associated diarrhea. Also has some "off-label" uses not pertinent here. ...Read more

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How effective is sandostatin (octreotide) on carcinoid tumor?

How effective is sandostatin (octreotide) on carcinoid tumor?

Good for symptoms: Sandostatin (octreotide) is a medication that decreases the release of hormones from carcinoid tumors, thereby decreasing symptoms of carcinoid (flushing, diarrhea). It may have some effects in slowing the growth of such tumors, but its main use is to treat symptoms of Carcinoid. It is effective for this is over 80% of patients with Carcinoid. ...Read more

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Can Sandostatin (octreotide) LAR be used as treatment of elevated 5-HIAA in aggressive type of systemic mastocytosis? Thank you. (repeated question)

Possibly: Possibly for symtomatic management. However, malignant GI diseases can be mistaken for systemic mastocytosis. Whereas 5HIAA is elevated in carcinoid syndrome, it usually is normal in SM. Aggressive systemic mastocytosis usually requires chemotherapy or imatinib. ...Read more

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Past wk have bloating and egg burps, starting in afternoon. I'm on Sandostatin (octreotide) LAR, got this b4, but not this long. Also swam in Jamaica river. What?

Past wk have bloating and egg burps, starting in afternoon. I'm on Sandostatin (octreotide) LAR, got this b4, but not this long. Also swam in Jamaica river. What?

H. pylori: Bloating and burping can be symptoms of an infection known as H. pylori. This bacteria is very common. How people get the germ is not known, but many people have it. Some have symptoms and some do not. There is a blood test available that can detect if you have H. pylori. You should be tested. Left untreated it can lead to stomach ulcers, esophagitis, and/or other serious problems. ...Read more

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How does glucagon increase splanchnic blood flow? Paramedic here, trying to wrap my head around octreotide.

How does glucagon increase splanchnic blood flow? Paramedic here, trying to wrap my head around octreotide.

CAMP modulated: It increases cAMP levels, leading to phosphorylation of myosin light chain kinase, modulating calmodulin complex sensitivity, leading to smooth muscle relaxation. ...Read more

Dr. Bernard King
255 Doctors shared insights

Octreotide (Definition)

Octreotide ...Read more