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Doctor insights on: Alternatives To Humira Enbrel

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Are there other alternatives to enbrel (etanercept) and humira?

Are there other alternatives to enbrel (etanercept) and humira?

Many!: Methotrexate, sulfasalazine, Imuran, and other non-biologics.

Other TNF-alpha inhibitors exist, such as Simponi and Remicade! ...Read more

Dr. Robert Lowe
125 Doctors shared insights

Etanercept (Definition)

Etanercept is an immune system suppressor which is a kind of ...Read more


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I was on humira and felt terrible, is enbrel (etanercept) any better?

Switching meds: The current recommendation is to try a medication with a different mechanism of action. That being said, before there were so many options, switching between Enbrel and Humira was quite common. Sometimes it helps, just as sometimes one pill in a class of drugs works better than another. ...Read more

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What's average amount of time people can take biologics (ex: humira (adalimumab) or enbrel) before developing an immunity to it? Do all patients develop immunity?

See below: Patients are more apt to develop resistance to biologic if they are not on methotrexate. However; not all patients are candidate to be on methotrexate. Some patients never have a problem and some do. It is hard to comment on the average amount of time because it is an individual phenomena. ...Read more

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Is enbrel (etanercept) or humira a narcotic drug?

Is enbrel (etanercept) or humira a narcotic drug?

No: Enbrel (etanercept) and Humira (adalimumab) are tumor necrosis factor-alpha (tnfa) blockers. They are not related to narcotic medications. ...Read more

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Is there a waiting period between changing from enbrel (etanercept) to humira? If so, how long? Then how long before humira begins to work?

Is there a waiting period between changing from enbrel (etanercept) to humira? If so, how long? Then how long before humira begins to work?

One week: I would start Humira one week after your last Enbrel (etanercept) injection. There is no hard and fast rule. I have seen Humira work as quickly as within two weeks and as long as three months. These medications should be given for at least three months before switching. Good luck. ...Read more

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Is there a difference in humira and enbrel (etanercept) treatment of psoriasis?

No great...: No great differences. Enbrel (etanercept) is once weekly and Humira is once every two weeks. They have similar efficacy in large trials, but differences exist between individuals! Both should be tried only after Methotrexate therapy has failed! ...Read more

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On actemra (tocilizumab) IV (dose increase in dec)and methotrexate for 5 mon now but still having bad flare ups. Tried humira, enbrel, etc. Since diagnosis in Dec 2013?

Your question is?: Your have not asked a question. This issue needs to be discussed with your rheumatologist. No one can give you specific advice over the internet without a complete history and exam. ...Read more

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With other tnf inhibitors such as humira and enbrel (etanercept) are there?

See list: In the usa, the available tnf inhibitors are Adalimumab (humira), Etanercept (enbrel), certolizumab pegol (cimzia), golimumab (simponi), and Infliximab (remicade). ...Read more

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What are the side effects of tnf inhibitors such as humira and enbrel (etanercept)?

See below: The important side effects that have been most extensively related to tnf blockers include: lymphoma, infections including tuberculosis, congestive heart failure, demyelinating disease, a lupus-like syndrome, induction of auto-antibodies, injection site reactions, and systemic side effects. ...Read more

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Was on humira (adalimumab) weekly&psoriasis came back. Now on enbrel&25mg methotraxte. Do u think psorias will clear? Y did humira (adalimumab) stop working? Stress overpower it?

Both work: It's your these medicines are effective. The reason medication stop working may depend on many factors. Sometimes the body develops resistance to a medication that is working fine. The resistance can occur because of antibodies against the drug. It can also occur because the mechanism of the disease of the illness can change differently at the molecular level. You doctor can better answer this. ...Read more

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Child has JRA failed enbrel and had side effects from it so dr gave choice humira or remicade (infliximab) Which is better? I'm confused snd do know what to do!

Child has JRA failed enbrel and had side effects from it so dr gave choice humira or remicade (infliximab) Which is better? I'm confused snd do know what to do!

TNF Inhibitors: All of the medications offered to your child work in similar ways the difference is how the meds are given. Humira (adalimumab) is an injection that can be done at home every two weeks, while remicaide is an IV medication that must be done in an infusion unit or hospital. These medication have similar side effects and benefits. My advice is try the medication that is least disruptive to your lifestyle. ...Read more

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Psoriasis+psor. Arthritis. Methotrexate 15mg for 2 mos. Already+humira weekly. Dr say stelera no good for arthr...Says remicade (infliximab) or enbrel maybe. Ok?

Nod to others:: Humira is a tnfa antibody, and is similar to envbrel. Remicade (infliximab) is an antibody to the tnfa receptor, so it works differently. But I would have tried you on leflunomide, and oral drug, before starting biologics. ...Read more

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What is it like to have any experience with blood monitoring for anti tnf therapy (humira/enbrel) whilst traveling for multi stop flights abroad?

What is it like to have any experience with blood monitoring for anti tnf therapy (humira/enbrel) whilst traveling for multi stop flights abroad?

See details: People who are stable on TNF biologics do not require blood test monitoring more than once every 3 months. Those in my practice who have been stable for years only have monitoring every 6 months. ...Read more

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My RA doc wants me to take Enbrel/ Humira (adalimumab). Very afraid of the side effects & I'm already blind in 1 eye. What else can I take instead?

My RA doc wants me to take Enbrel/ Humira (adalimumab). Very afraid of the side effects & I'm already blind in 1 eye. What else can I take instead?

Talk to RA doctor: These are issues which need be discussed with your RA doctor. In medicine, most decisions made are based on risk/benefit ratio and without knowing that, it is impossible to provide you with an answer in this type of interaction. ...Read more

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Rheumatoid arthritis for 7 yrs. On methotrexate & prednisone. Tried so many drugs (orencia, enbrel, (etanercept) humira...). Feeling defeated. What else can I try?

Rheumatoid arthritis for 7 yrs. On methotrexate & prednisone. Tried so many drugs (orencia, enbrel, (etanercept) humira...). Feeling defeated. What else can I try?

Other choices: Some older drugs such as Plaquenil may help, especially with fatigue. There are also newer drugs that act via different mechanisms such as actemra (tocilizumab). I assume the diagnosis of RA is definite. If not, retest other possibilities. An exercise program may be very beneficial, especially if you start slowly and build up with hurting yourself. Don't give up hope. You can get better. ...Read more

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RA + psoriasis. MTX allergy. Enbrel (etanercept) non effective. Humira semi-effective but Vectra score 30 with extreme fatigue. MD wants to try Xeljanz?

RA + psoriasis. MTX allergy. Enbrel (etanercept) non effective. Humira semi-effective but Vectra score 30 with extreme fatigue. MD wants to try Xeljanz?

RA + psoriasis: There are a number of newer medications that could help you. Xeljanz works by disrupting cytokine and growth factor signaling pathways. A trial of the medication is useful to see whether it helps you. Other medications that might help include Remicade (infliximab) and Apremilast ...Read more

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Besides enbrel (etanercept) and humeria what are other biolgics or infusions can a. 7 year old take for juvenile idiopathic arthrits?

See list: Remicade, Rituxan, Actemra, Simponi (golimumab), (golimumab) Cimzia, Orencia. Remicade, Simponi (golimumab) and Cimzia are TNF agents. ...Read more

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Dear doctors, as a person with ankylosing spondylitis, could you tell about the price of tnf-inhibitors, such as etanercept, infliximab, adalimumab?

Dear doctors, as a person with ankylosing spondylitis, could you tell about the price of tnf-inhibitors, such as etanercept, infliximab, adalimumab?

See below: They run about 4figures/month.---if you have not insurance, you may qualify to receive the drug for free directly from the pharmaceutical company. Talk to your rheumatologist about this. ...Read more

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Child has injection site reactions on enbrel and vomits after getting shot even with Zofran (ondansetron) what would be a good alternative drug for JRA?

Child has injection site reactions on enbrel and vomits after getting shot even with Zofran (ondansetron) what would be a good alternative drug for JRA?

Other biologic.: The details of your child's history and past treatments are unknown, of course, but one could consider an alternative biologic. Each one is designed differently than others.
I urge to set up a follow up with your child's pediatric rheumatologist to discuss further. Good luck and hope they feel better. ...Read more

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My wife uses humira (adalimumab) to treat her psoriasis but it costs $1700/month. Is there a cheaper alternative?

Methotrexate: Has your doctor told you about patient support from abbott for its Humira (adalimumab) product? If not check with him/her. Methotrexate is a possible low cost alternative. ...Read more

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Is there a drug that is less expensive and can be used as a alternative to humira (adalimumab)?

Is there a drug that is less expensive and can be used as a alternative to humira (adalimumab)?

No: Humira (adalimumab) is a biologic? Infliximab is more expensive. Other medications may be an option, but this should be discussed with ourngastroenterologist. ...Read more

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Is there a drug that's less expensive and can be used as a alternative to humira (adalimumab) for rheumatoid arthritis?

Is there a drug that's less expensive and can be used as a alternative to humira (adalimumab) for rheumatoid arthritis?

YES: There are multiple drugs for arthritis cheaper than humira. Pills like methotrexate, sulfasalaxine, Plaquenil (hydroxychloroquine) and Leflunomide can be used alone or in combination. There is also an injectable form of Methotrexate that can sometimes be more effective. Prednisone can also be taken. Non-steroidal anti-inflammatories can be used. Depending on your insurance, another biologic may be cheaper than humira. ...Read more

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Does enbrel (etanercept) cause a bad headache?

Does enbrel (etanercept) cause a bad headache?

Side effect: A headache is a common and less serious side effect while on enbrel (etanercept).
Your physician prescribed this medication because the benefits of Enbrel (etanercept) are greater than the risk of side effects.
Most people do not have serious side effects. ...Read more

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How to boost your immune system after enbrel (etanercept)?

How to boost your immune system after enbrel (etanercept)?

See below: Once you have stopped taking enbrel, (etanercept) the immune system should become more responsive on its own. There is no way to "boost" the immune system that is of any scientific merit. ...Read more

Dr. Robert Lowe
143 Doctors shared insights

Enbrel (Definition)

Enbrel is an immune system suppressor which is a kind of ...Read more


Dr. Robert Lowe
177 Doctors shared insights

Adalimumab (Definition)

Adalimumab is an arthritis therapy which is a ...Read more