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Doctor insights on: Alternative Treatments For Pleomorphic Adenoma

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Pleomorphic (Definition)

We use the term pleomorphic often in pathology; it literally means "many shapes". Pleomorphic cells in a tumor may tell of the genetic instability that's central to cancer, but the benign pleomorphic adenoma of the salivary glands merely has many different tissue types. The ...Read more


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Hi. I need help. Will you please tell me or explain to me the pathophysiology of pleomorphic adenoma? Thanks

Hi. I need help. Will you please tell me or explain to me the pathophysiology of pleomorphic adenoma? Thanks

Little to it: The anatomic pathology of pleomorphic adenoma is amazingly complex, and we are learning a bit about its molecular biology. The lesions are benign but locally destructive, especially endangering the facial nerve if in the parotid. Wide excision is required as the lesion sends out projections. Around 1% is the site of origin for a real cancer. ...Read more

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I ve 1.8cm *1.3cm pleomorphic adenoma on superficial lobe of patotid gland. Scared to do surgery. Possible complications of surgery? Postoperative care?

I ve 1.8cm *1.3cm pleomorphic adenoma on superficial lobe of patotid gland. Scared to do surgery. Possible complications of surgery? Postoperative care?

Surgery mandatory: The benign tumor will just get bigger and bigger and the risks of nerve damage will be higher. Procedure safe with an experienced surgeon.
Recommend Jeffrey Spiro, M.D., Professor, Department of Surgery. U Conn Medical Center, Framingham CT
860-679-2804 ...Read more

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I ve pleomorphic adenoma in parotid gland. Dr performed fnac. Does fnac spread tumor cells. Scared. Size is 1.5cm. Entire gland needs removal?

Spread not likely: Pleomorphic adenoma is benign and there is minimal risk of spread with a fine needle aspirate. Removal is warranted as the lesion can become larger. ...Read more

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If you had a benign pleomorphic adenoma in a minor salivary gland for approx 5 years would you have it surgically removed?

If you had a benign pleomorphic adenoma in a minor salivary gland for approx 5 years would you have it surgically removed?

Yes: These lesions can grow and can undergo malignant transformation. I almost always rec excision. Find an ENT doctor who does frequent parotidectomies with facial nerve dissections. ...Read more

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Could my son get cancer if he was diagnosed with pleomorphic adenoma, 3 tumors in the neck and 1 in cheek?

Rarely: Pleiomorphic adenomas are benign tumors of saliva glands. It is unusual for them to be in the neck itself, but they can arise "rests" of salivary tissue in the neck. They tend not to spread to other parts of the body but can grow back in the areas where they arose in about 20% of patients who had surgery. Rarely they can turn cancerous and spread to other organs. Best wishes. ...Read more

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My son was diagnosed with pleomorphic adenoma, 3 tumors in the neck and 1 in cheek. Could this become cancer?

Pleomorphic adenomas: These salivary gland tumors are usually benign. If the tumor is of the mixed type it could become cancerous ...Read more

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My mum was diagnosed with pleomorphic parotid adenoma and she has a heart condition. Is an operation really necessary? My mum is 79

My mum was diagnosed with pleomorphic parotid adenoma and she has a heart condition. Is an operation really necessary? My mum is 79

An operation: Is generally necessary. Ask your doctor whether or not her medical risks outweigh benefits of surgery, because a lot depends on the severity of her heart condition. ...Read more

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What do you suggest if my son was diagnosed with pleomorphic adenoma, 3 tumors in the neck and 1 in cheek. Can this turn into cancer?

What do you suggest if my son was diagnosed with pleomorphic adenoma, 3 tumors in the neck and 1 in cheek. Can this turn into cancer?

Early ENTinvolvement: Close follow-up with the ENT, surgical resection is required. Yes, these have a high rate of malignant transformation. ...Read more

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I have had surgery twice of the parotid gland (pleomorphic adenoma). Now from last 1 month my intra parotid lymph nodes are swollen, why?

Many possible reason: If you are certain this is an intraparotid lymph node (as opposed to a nodule of recurrence of pleomorphic adenoma), there could be many possible causes ranging from some infection, to inflammatory diseases either specific to the parotid or more general, to some other tumor. The person who did your most recent parotid surgery is probably in the best position to answer this question. ...Read more

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Will hole in roof of mouth to sinus area from pleomorphic adenoma removal heal closed or will I require another surgery?

Need more info: If the adenoma was removed recently and the hole is small, I would say that healing by secondary intention could occur. However, without knowing more about your case, I cannot say more except that you need to ask your surgeon that question. ...Read more

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Few days ago I have left parotid pleomorphic adenoma Specimen Type left superfacial parotid gland but after surgery I have salivary leakage probl?

Few days ago I have left parotid pleomorphic adenoma Specimen Type left superfacial parotid gland but after surgery I have salivary leakage probl?

Fistula: It sounds like you have a salivary fistula which is a rare complication of partial parotidectomy. Usually will close spontaneously in a few weeks and very rarely persists for months or chronically. However, since you are "fresh post-op"only a few days after surgery, PLEASE call the surgeon and make sure s/he sees you. Get well soon ...Read more

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Small pleomorphic adenoma (<2cm) on postero inferior part of superficial parotid gland. Traditional incision needed? Anyone do micro parotidectomy in ct?

Small pleomorphic adenoma (<2cm) on postero inferior part of superficial parotid gland. Traditional incision needed? Anyone do micro parotidectomy in ct?

Traditional incision: Pleomorphic adenoma of the superficial lobe of parotid requires removal of the superficial lobe. This operation is not performed on the lobe per se but on identifying the facial nerve and its branches and lifting the lobe off the nerve. The incision is designed to give landmarks that define the trunk of the nerve as it comes out of the stylomastoid foramen. Procedure this way is under 1 hr. ...Read more

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What alternative treatments exist for orchitis?

What alternative treatments exist for orchitis?

None that I'm aware: Orchitis is either a viral or bacterial infection of the testicle. If bacterial you need antibiotics. If you are sexually active get checked for a sexually transmitted infection. ...Read more

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What are the possible alternative treatments for dystonia?

What are the possible alternative treatments for dystonia?

Dystonia: Stopping the medication that is causing the dystonia, if it is is sevesre IV Benadryl (diphenhydramine) helps. ...Read more

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Could I have success with alternative treatments for alzhiemers?

Could I have success with alternative treatments for alzhiemers?

Possibly: AD is an incurable degenerative disease of the brain. There have been some studies using medium chain triglycerides to 'feed' the brain (Axona). Recently a study supported the use of hi dose Vit E. Other supplements include Vinpocetine and phosphatidyl serine. Be careful even with supplements and 'natural' products- they maybe unsafe or have interactions with other products or medications. ...Read more

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What are alternative treatments for paralysis?

What are alternative treatments for paralysis?

Depends on cause: With paralysis from a stroke or from a spinal cord injury, the mainstays of treatment start with physical and occupational therapy. The goal is to retrain the muscles and decrease disuse atrophy and spasticity (stiffness). There is a lot of research being done on stem cell transplants and electrocortical activation of prosthetics. We anxiously await their progress. ...Read more

Dr. Murthy Andavolu
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