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Doctor insights on: Alternative Treatments For Minimal Change Disease

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Is there any new and better treatment for minimal change disease? Im 25yrs on steroids. Was diagnoised wit mcd in 2007. Thank u in advance sir.

Is there any new and better treatment for minimal change disease? Im 25yrs on steroids. Was diagnoised wit mcd in 2007. Thank u in advance sir.

Primary tx: Steroids are still primary treatment for minimal change disease; however, treatment is usually limited, as remission is often achieved in a matter of months, with a slow taper off over the following two years or so. If yours can't be tapered off, there are alternatives such as Cyclophosphamide that can be used as steroid-sparing agents, but these require discussion with your nephrologist. ...Read more

Dr. Donald Batisky
84 doctors shared insights

Nephrotic Syndrome (Definition)

A condition caused by dysfunction of the kidney in which large amount of protein leak into the urine. Typically three components of the syndrome are 1) protein greater than 3.5 grams per day, 2) low serum albumin, and ...Read more


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What is a treatment for nephrotic syndrome?

What is a treatment for nephrotic syndrome?

Proper medication: Minimal change (or nil) disease. Correctly diagnosed by biopsy but frequently diagnosed by the symptoms of proteinuria, edema and intact renal function with a bland urine sediment. This responds to steroid therapy most of the time. The presence of blood in the urine, or failure to respond to steroids indicates need for biopsy of kidney with therapy based on those results. Case needs nephrologist. ...Read more

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What is the latest treatment for nephrotic syndrome in children?

Steroids: Kids with nephrotic syndrome spill protein in their urine due to inflammation of the membrane that filters blood. This leads to swelling throughout the body as there is not enough protein in the blood to prevent fluid from leaks out of the vessels. Treatment is steroids to knock down the inflammation and stop the proteins from leaking out. The problem usually resolves fairly quickly when treated. ...Read more

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Can you conceive after you've had treatment for nephrotic syndrome?

Can you conceive after you've had treatment for nephrotic syndrome?

See below: Some treatment for nephrotic syndrome may involve use of agents which can suppress ovulation or decrese sperm count, and it may be difficult to conceive, but this is not a definite side effect and needs to be discussed with your doctor. ...Read more

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How effective is the 'rituximab' treatment for nephrotic syndrome?

How effective is the 'rituximab' treatment for nephrotic syndrome?

Rituximab: In an article at this link: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3358759/, the article suggests that Rituximab is not effective in forms of INS resistant to steroids and calcineurin inhibitors. Ask the physician treating the patient for more information. Good luck. ...Read more

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What is the dose and duration of treatment with prednisolone in the management of nephrotic syndrome?

What is the dose and duration of treatment with prednisolone in the management of nephrotic syndrome?

Variable by case: Only your doctor can determine the type and duration of treatment. Followup studies are needed to monitor progress. Often the dose can be tapered after the urine protein loss declines and other factors normalize, but all depends on your individual response to therapy. ...Read more

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Can medical marijuana be used in the treatment of nephrotic syndrome? Looking to replace existing medications with side-effect-friendlier ones.

Can medical marijuana be used in the treatment of nephrotic syndrome? Looking to replace existing medications with side-effect-friendlier ones.

Marijuana: I don't think it is a good idea while you have nephritic syndrome. Please discuss this with the doctor seeing you for the nephritic syndrome. Hope all goes well. ...Read more

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Can you tell me if i could get the lap band surgery with minimal change disease?

Can you tell me if i could get the lap band surgery with minimal change disease?

Here are some...: This Q has been longstanding with no answering. Despite not an expert in bariatrics, based on my lifelong digestion of medical knowledge coupled with common sense, I could not see any interaction between both through uneventful lap band surgery since minimal change disease denotes the usually uneventful kidney changes from various reasons. More? Ask your doctor straight, not circuitous timely. ...Read more

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How dangerous is minimal change disease when steroid resistant? He is 4 yrs old....

How dangerous is minimal change disease when steroid resistant?  He is 4 yrs old....

Poor control ; ...: There is no uniform approach for the individuals with steroid-resistant nephrotic syndrome. Clinical trials utilizing cyclosporin, tacrolimus, or Mycophenolate Mofetil (mmf) with corticosteroid show variable success rate of inducing remission. Therefore, poor control of proteinurua and edema and higher rate of drug toxicity is common. ...Read more

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Minimal change disease prognosis?

Minimal change disease prognosis?

Good: With ace inhibitors and steroids it can usually be kept in remission. Compliance with the physicians care plan is essential. It is a good idea to have a nephrologist helping you with this. ...Read more

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Had nephrotic syndrome 12 yrs ago..minimal change disease. Should I always be on bp drug to protect kidneys? I've been on Losartan and my new dr disc

Had nephrotic syndrome 12 yrs ago..minimal change disease.  Should I always be on bp drug to protect kidneys? I've been on Losartan and my new dr disc

See answer: Minimal Change Disease is one of the more common and treatable kidney diseases. >90% of patients respond to oral steroids, with most having a complete remission. However, >50% of the adults who go into remission will relapse at some point. A nephrologist is the best MD to follow you and determine what medications are best for you based on your BP, edema, renal function, urine protein amount, etc. ...Read more

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Does kidney disease specifically minimal change disease have any connection with allergies?

Does kidney disease specifically minimal change disease have any connection with allergies?

A possible trigger: The cause of minimal change disease is not fully known but it is believed to be an immune disorder in which t cells release a cytokine that damages the epithelial foot processes of the glomeruli. This leads to a leakage of Albumin by the kidney. Certain events such as a viral infection, an allergic reaction, a bee sting, or an immunization may trigger an attack of mcd. ...Read more

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I have minimal change disease. I want to start using wild yam 2000mg daily as a contraception option. Will this herb damage kidneys more?

I have minimal change disease. I want to start using wild yam 2000mg daily as a contraception option. Will this herb damage kidneys more?

Wild Yam: I do not know of any studies that show that wild yam helps with contraception but it may cause scarring of the kidneys based on a study in 2008 "food and chemical toxicology" journal. Taking unregulated herbs can be a very risk proposition as no one is 100% sure what potential side effects you may have. ...Read more

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Can secondary infections (sinusitis) cause minimal change disease to flare up...spilling protein.

Can secondary infections (sinusitis)  cause minimal change disease to flare up...spilling protein.

Not really: get a repeat urine analysisi, culture and kidney function studies. You may need a 24 hour urine analysisi and/or a reanl ultrasound if symtoms persisit. ...Read more

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Are there any alternative treatments to alleviate the symptoms of lou gehrig's disease?

Are there any alternative treatments to alleviate the symptoms of lou gehrig's disease?

No, none!: Would be nice to find such approaches in this devastating condition, but does NOT exist. Even our approved medication, Riluzole does very little. ...Read more

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What are the natural alternative treatments to inherited bone loss disease?

What are the natural alternative treatments to inherited bone loss disease?

Exercise: Get precise advice from your primary doctor or mineral metabolism specialist, because your type may need more than exercise. In general though, bone, like muscle, gets stronger with use. So weight bearing exercise (walking, running) can strengthen back (spine) and leg bones. Weight training can help bone and muscle strength in those areas and in the arms. ...Read more