Doctor insights on:
Alternative Treatments For Minimal Change Disease
Is there any new and better treatment for minimal change disease? Im 25yrs on steroids. Was diagnoised wit mcd in 2007. Thank u in advance sir.
Primary tx: Steroids are still primary treatment for minimal change disease; however, treatment is usually limited, as remission is often achieved in a matter of months, with a slow taper off over the following two years or so. If yours can't be tapered off, there are alternatives such as Cyclophosphamide that can be used as steroid-sparing agents, but these require discussion with your nephrologist. ...Read more
Proper medication: Minimal change (or nil) disease. Correctly diagnosed by biopsy but frequently diagnosed by the symptoms of proteinuria, edema and intact renal function with a bland urine sediment. This responds to steroid therapy most of the time. The presence of blood in the urine, or failure to respond to steroids indicates need for biopsy of kidney with therapy based on those results. Case needs nephrologist. ...Read more
Steroids: Kids with nephrotic syndrome spill protein in their urine due to inflammation of the membrane that filters blood. This leads to swelling throughout the body as there is not enough protein in the blood to prevent fluid from leaks out of the vessels. Treatment is steroids to knock down the inflammation and stop the proteins from leaking out. The problem usually resolves fairly quickly when treated. ...Read more
What is the dose and duration of treatment with prednisolone in the management of nephrotic syndrome?
Can medical marijuana be used in the treatment of nephrotic syndrome? Looking to replace existing medications with side-effect-friendlier ones.
Marijuana: I don't think it is a good idea while you have nephritic syndrome. Please discuss this with the doctor seeing you for the nephritic syndrome. Hope all goes well. ...Read more
Here are some...: This Q has been longstanding with no answering. Despite not an expert in bariatrics, based on my lifelong digestion of medical knowledge coupled with common sense, I could not see any interaction between both through uneventful lap band surgery since minimal change disease denotes the usually uneventful kidney changes from various reasons. More? Ask your doctor straight, not circuitous timely. ...Read more
Poor control ; ...: There is no uniform approach for the individuals with steroid-resistant nephrotic syndrome. Clinical trials utilizing cyclosporin, tacrolimus, or Mycophenolate Mofetil (mmf) with corticosteroid show variable success rate of inducing remission. Therefore, poor control of proteinurua and edema and higher rate of drug toxicity is common. ...Read more
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