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Doctor insights on: Alternative Treatments For Minimal Change Disease

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Is there any new and better treatment for minimal change disease? Im 25yrs on steroids. Was diagnoised wit mcd in 2007. Thank u in advance sir.

Is there any new and better treatment for minimal change disease? Im 25yrs on steroids. Was diagnoised wit mcd in 2007. Thank u in advance sir.

Primary tx: Steroids are still primary treatment for minimal change disease; however, treatment is usually limited, as remission is often achieved in a matter of months, with a slow taper off over the following two years or so. If yours can't be tapered off, there are alternatives such as Cyclophosphamide that can be used as steroid-sparing agents, but these require discussion with your nephrologist. ...Read more

Dr. Donald Batisky
77 doctors shared insights

Nephrotic Syndrome (Definition)

Nephrotic syndrome is caused by dysfunction of the kidney in which large amount of protein leak into the urine. Typically three components of the syndrome are 1) protein greater than 3.5 grams per day, 2) low serum albumin, and ...Read more


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What is a treatment for nephrotic syndrome?

What is a treatment for nephrotic syndrome?

Proper medication: Minimal change (or nil) disease. Correctly diagnosed by biopsy but frequently diagnosed by the symptoms of proteinuria, edema and intact renal function with a bland urine sediment. This responds to steroid therapy most of the time. The presence of blood in the urine, or failure to respond to steroids indicates need for biopsy of kidney with therapy based on those results. Case needs nephrologist. ...Read more

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What is the latest treatment for nephrotic syndrome in children?

Steroids: Kids with nephrotic syndrome spill protein in their urine due to inflammation of the membrane that filters blood. This leads to swelling throughout the body as there is not enough protein in the blood to prevent fluid from leaks out of the vessels. Treatment is steroids to knock down the inflammation and stop the proteins from leaking out. The problem usually resolves fairly quickly when treated. ...Read more

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Can you conceive after you've had treatment for nephrotic syndrome?

Can you conceive after you've had treatment for nephrotic syndrome?

See below: Some treatment for nephrotic syndrome may involve use of agents which can suppress ovulation or decrese sperm count, and it may be difficult to conceive, but this is not a definite side effect and needs to be discussed with your doctor. ...Read more

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How effective is the 'rituximab' treatment for nephrotic syndrome?

How effective is the 'rituximab' treatment for nephrotic syndrome?

Rituximab: In an article at this link: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3358759/, the article suggests that Rituximab is not effective in forms of INS resistant to steroids and calcineurin inhibitors. Ask the physician treating the patient for more information. Good luck. ...Read more

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What is the dose and duration of treatment with prednisolone in the management of nephrotic syndrome?

What is the dose and duration of treatment with prednisolone in the management of nephrotic syndrome?

Variable by case: Only your doctor can determine the type and duration of treatment. Followup studies are needed to monitor progress. Often the dose can be tapered after the urine protein loss declines and other factors normalize, but all depends on your individual response to therapy. ...Read more

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Can medical marijuana be used in the treatment of nephrotic syndrome? Looking to replace existing medications with side-effect-friendlier ones.

Can medical marijuana be used in the treatment of nephrotic syndrome? Looking to replace existing medications with side-effect-friendlier ones.

Marijuana: I don't think it is a good idea while you have nephritic syndrome. Please discuss this with the doctor seeing you for the nephritic syndrome. Hope all goes well. ...Read more

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Can you tell me if i could get the lap band surgery with minimal change disease?

Can you tell me if i could get the lap band surgery with minimal change disease?

Here are some...: This Q has been longstanding with no answering. Despite not an expert in bariatrics, based on my lifelong digestion of medical knowledge coupled with common sense, I could not see any interaction between both through uneventful lap band surgery since minimal change disease denotes the usually uneventful kidney changes from various reasons. More? Ask your doctor straight, not circuitous timely. ...Read more

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How dangerous is minimal change disease when steroid resistant? He is 4 yrs old....

How dangerous is minimal change disease when steroid resistant?  He is 4 yrs old....

Poor control ; ...: There is no uniform approach for the individuals with steroid-resistant nephrotic syndrome. Clinical trials utilizing cyclosporin, tacrolimus, or Mycophenolate Mofetil (mmf) with corticosteroid show variable success rate of inducing remission. Therefore, poor control of proteinurua and edema and higher rate of drug toxicity is common. ...Read more