Doctor insights on:
Alternative Treatments For Ig G Deficiency
Could an unknown virus (that causes IgG deficiency) be passed from father to son, & thereby present as a genetic IgG deficiency& in reality be viral?
Can an allergist/immunologist ever help with chronic inflammatory polyneuropathy? Have seen neuro, but have been told I have IgG deficiency as well.
Together: There is an overalp, and a neuroimmunologist should be able to treat it and if in doubt, an allergist can prescribe ivig if needed. Your neurologist should be able to tell you if they can treat the igg deficiency or not. ...Read more
Can having a IgG deficiency affect your WBC if a infection is present- I have mastoiditis it spread to other bones. But my WBC is normal. Why?
I was diagnosed by allergist with IGA & IGG deficiency due to recurrent infections. Had 2 miscarriages within 3 yrs. Can this be cause of miscarriage?
Unlikely: Not a direct cause,? infection leads to miscarriage, may be, but even individuals without your condition miscarry for no known reason. IgA deficiency is the most common primary immunodeficiency amongst the already rare immunodeficiency disorders, many afflicted persons are asymptomatic and lead normal lives, follow up with your immunologist/allergist for possible IVIG replacement therapy, good luck ...Read more
I recently miscarried at 7 weeks. Diagnosed with IGA and possibly IGG deficiency. Also have bicornuate uterus. Can IGG and IGA def. Cause miscarriage?
Clarification: See your doctor to go over the test results to get clarification. It is unclear here if your doctor was testing IgG and IgA as part of an antiphospholipid antibody workup for miscarriage or if you are referring to the genetic disorder of the immune system referred to as IgA deficiency. The impact on pregnancy depends on the diagnosis. ...Read more
What would prevent me from having a tummy tuck procedure done. I have type 2 diabetes and an IgG deficiency (hypogammaglobulinemia). I have had ivig.?
Medical Clearance.: Patients who have “medical conditions” should have these conditions under good control prior to undergoing elective surgery. Therefore, best to be evaluated by your internist to check how well these conditions are “optimized” and whether you are a good candidate to proceed with elective surgery. It is very likely that your plastic surgeon will ask for this medical clearance. Best wishes. ...Read more
Which malignancies and/or granulomatous conditions are seen in individuals that only have IgG subclass 3 (igg3) deficiency?
Is there CSF IgG subclass deficiency? I have lowish IgG and IgG subclass deficiencies (1, 3, 4) and CSF IgG of 685.
Great question: You already know that most folks who are discovered to have real igg3 deficiency are troubled primarily by recurrent nasal sinus infections. Until we know whether there's one of more genes for this, or whether it's the result of some other change in the immune system (igg3 can drop after other illnesses), I think the mainstream medical community will remain undecided. Glad you're proactive. ...Read more
My father has had low IgG levels for a year... Other igs are normal. Could this be a problem? His pcp suggested perhaps some immune deficiency.
Possibly: Igg being low can signal an immune deficiency. But more important than the amount is how well the igg works to fight infections. If he does not have many infections, this level might be his "normal". He should see an immunologist, who can tease out the likelihood of immune deficiency from your dad's history as well as lab tests (that look how well his immune system responds to vaccines, e.g.). ...Read more
I have an IgG subclass 3 deficiency. What diseases/disorders are associated with this? Are you more likely to acquire certain diseases/disorders?
IgG3 subclass def: Igg has four types. Igg3 is involved in fighting against carbohydrate covered infectious organisms. Igg1 is the most numerous and igg3 is of much less quantity. If you have normal antibody titers to vaccines, then you are likely safe. I would simply monitor all of your immunoglobulin levels yearly. ...Read more
I read that IgG subclass deficiencies are associated with fibromyalgia and chronic fatigue syndrome. Is this true? If so, what is the connection?
IGG: Igg are sensitivities for foods or substances and cause significant gut inflammation. These then lead to impermeable or leaky gut. This inflammation can lead to joint and muscle pain. The fatigue is usually caused by the poor absorption of the cofactors needed in the body to produce energy. ...Read more
Yes: It is possible to have malfunction of immunoglobulins or low levels in b cell disorders. A subclass deficiency by itself is usually not clinically significant and does not warrant treatment but if an underlying b cell disorder exists, it should be remedied. ...Read more
Have a mutation for immune deficiency (CVID2/IGAD2) associated with TACI. Normal IgA, IgM & IgG but long history of severe infections. How to test it?
?: Not adding up, you can't literally have those conditions, repeated severe infections and normal measures of Ig subtypes. You need to be re-evaluated, you may simply have IgG subclass deficiency, or specific antibodies deficiency, testing for recall antigens for tetanus and pneumococcus, pre and post vaccination can prove it, treatment remains the same: IVIG therapy. Too complex for this limited platform ...Read more
If u have Vitamin D deficiency, does this have any effect on immunoglobulin levels (IgG, IgM...etc.)? Would low Vitamin D cause lower IgG or IgM?
Varicella zoster igg level 2339. What does it mean, a recent infection or general immune deficiency?
My ccp ab, IgG was 221 what would be the safest treatment to go on? Will it bring that number down?
It depends on other: It depends on other tests and your exam. The ccp antibody is seen with rheumatoid. Your rheumatologist will interpret this in conjunction with lab findings. Also your x-rays will determine what medication you will go on as well your medical history. The number that we would want to reduce instead of the ccp is any elevated levels of inflammation such sed rate and crp. Hope that helps. ...Read more
My 12 month old daughter's IgA and IgG levels are low. Is this serious and what are the treatments?
See an immunologist: The levels might not be low for her age, normal levels depend on specific age. If they are truly low, it might be a transient deficiency that could resolve with time, or she may have an immunodeficiency. ...Read more
My 2yr son has been doing infusion treatment for over a yr now for. Low IgG and his IgM is still very low what does thar mean?
Trace IgM: Most immune globulin infusions primarily contain IgG with only trace amounts of IgA and IgM. Typically we monitor only IgG peak and trough levels. ...Read more
What is monoclonal protein? How does this affect the body? What is IgG lamda and it's affects. What are the treatments.? What can this thing turn int?
Spike: You probably have either a monoclonal gammopathy of uncertain significance, which is a non-problem but has perhaps a 1% chance per year of turning into plasma cell ("multiple") myeloma, or myeloma itself. You need to get with your physician and find out which. Good luck. ...Read more
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