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Doctor insights on: Alternative Treatments For Graft Versus Host Disease

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Are there any new treatments or drugs that can help with graft versus host disease?

Are there any new treatments or drugs that can help with graft versus host disease?

Mainstays of therapy: for GVHD are corticosteroids; either systemic (prednisone) or topically, e.g triamcinolone. Cyclosporine and tacrolimus help minimize corticosteroid exposure. Sirolimus and mycophenylate mofetil are effective, as are methotrexate and azathioprine in refractory cases. B-cell therapies such as rituximab and bortezomib are promising. PUVA and ECP are light therapies with less systemic side effects. ...Read more

Graft (Definition)

Tissues from one location are transferred to another . Also refers to ...Read more


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What is an appropriate diet for someone with graft-versus-host disease?

What is an appropriate diet for someone with graft-versus-host disease?

A healthy diet: is important for GVHD patients, but it may not be much different than for the rest of us. If the mouth or gut is affected, then the key is to find foods the patient can tolerate. Sometimes simple, easy to digest foods are best. If a GVHD patient requires corticosteroid treatment (prednisone) then a healthy diet should be balanced by exercise to prevent weight gain and loss of muscle mass. ...Read more

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Can radiology be used to diagnose graft-versus-host disease?

Physical examination: ...and biopsies are the mainstay of diagnosis of graft vs. host disease. Radiology is used mostly to exclude other causes of symptoms, such as an ultrasound of the liver to exclude biliary obstruction, or CT of the chest to exclude infection. ...Read more

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Hodgkins lymphoma graft-versus-host disease, what is this?

Cellular immunity: Graft vs. host disease (GVHD) occurs when T lymphocytes from a donor cause inflammation in the normal tissues of a patient. This is a common side effect of allogeneic bone marrow transplants because billions of T cells are infused along with the bone marrow stem cells. It can also occur as a rare, unintended consequence of blood transfusion in Hodgkins patients. ...Read more

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What is the medical definition of graft-versus-host disease?

GVHD: occurs when bone marrow stem cells and/or immune cells have been engrafted from one individual into another. Except in identical twins, differences in cellular antigens cause engrafted cells to react against the host tissues and cause an inflammatory injury. Acutely, symptoms may affect the skin, liver, or gut; whereas chronic GVHD may affect the eyes, mouth, fascia, and lungs. ...Read more

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What is the difference between graft-versus-host disease and rejection?

GVHD is a reaction..: of engrafted immune cells against the patients healthy tissues. It leads to inflammation and side effects in a variety of tissues. Rejection is the opposite. It is a reaction of the patients immune system against the engrafted cells. In the case of a bone marrow transplant, rejection would cause disappearance of the cells in the marrow and a drop in blood cell production. ...Read more

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What are the symptoms of graft-versus-host disease?

There can be many...: Acute GVHD presents as a skin rash, gut symptoms (nausea or diarrhea) or jaundice. Chronic GVHD commonly causes dry eyes and dry mouth but they can also get quite sore. More serious symptoms of chronic GVHD include sclerosis (scarring or thickening) of the skin, or reduced flexibility due to connective tissue inflammation (fascitis). Pulmonary airflow obstruction may cause shortness of breath. ...Read more

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Are there any alternative treatments to alleviate the symptoms of lou gehrig's disease?

Are there any alternative treatments to alleviate the symptoms of lou gehrig's disease?

No, none!: Would be nice to find such approaches in this devastating condition, but does NOT exist. Even our approved medication, Riluzole does very little. ...Read more

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What are the natural alternative treatments to inherited bone loss disease?

What are the natural alternative treatments to inherited bone loss disease?

Exercise: Get precise advice from your primary doctor or mineral metabolism specialist, because your type may need more than exercise. In general though, bone, like muscle, gets stronger with use. So weight bearing exercise (walking, running) can strengthen back (spine) and leg bones. Weight training can help bone and muscle strength in those areas and in the arms. ...Read more