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Doctor insights on: Alternative Treatments For Familial Mediterranean Fever

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What are the latest treatments for familial mediterranean fever?

What are the latest treatments for familial mediterranean fever?

Best, not latest: Fmf is treacherous -- your mainstay of therapy is still Colchicine to keep the disease at bay and prevent amyloidosis which is horrible. The interleukin 1 receptor antagonist Anakinra is a pricey adjunct that's needed only by a minority of patients. ...Read more

Dr. Peter Anton
45 Doctors shared insights

Familial Mediterranean Fever (Definition)

Familial mediterranean fever, also called familial paroxysmal or recurrent polyserositis is an inherited condition characterized by transient recurring attacks of abdominal pain, fever, pleurisy (chest pain), arthritis, and rash. The condition ...Read more


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Hi. I want to know. What is the best treatment for familial mediterranean fever other than tacking colchicine, my brother is 24 years old, ?

Hi. I want to know. What is the best treatment for familial mediterranean fever other than tacking colchicine, my brother is 24 years old, ?

See details: Colchicine forms the basis of therapy. However, there are 2 other drugs that can be effective. These are Anakinra and rilonocept. I have personally seen excellent results with anakinra. ...Read more

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Is there a herbal treatment for familial mediterranean fever?

Is there a herbal treatment for familial mediterranean fever?

Apparently not.: The treatment for this disease is mainly analgesics and nsaids like diclofenac. Colchicine, a drug mainly used in gout, decreases attack frequency in patients, and adding Anakinra to the Colchicine regimen is successful in cases resistant to Colchicine therapy alone. ...Read more

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Can familial mediterranean fever be detected easy?

Can familial mediterranean fever be detected easy?

Not really.: The diagnosis of this disorder is made with a combination of clinical analysis and testing. A history of typical attacks of fever and abdominal or joint pain in mediterranian groups like armenians or arabs is highly suggestive, with acutely high levels of c-reactive protein, wbc, and possibly evidence of renal failure. Genetic tests to detect mefv gene mutations and Metaraminol test can be done. ...Read more

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Can familial mediterranean fever be detected early?

Can familial mediterranean fever be detected early?

Rare condition: Fmf often presents as fever of undetermined origin. If you are of appropriate ethnic background, have episodes of fever with abdominal pain and other suggestions of polyserositis and are without symptoms between attacks the illness is suspected and there are now molecular testing techniques for hereditary periodic fevers. Without these symptoms, very difficult to suspect. ...Read more

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Familial mediterranean fever: can the basic problem be treated?

Familial mediterranean fever: can the basic problem be treated?

Yes: There are available and effective treatments for fmf including Colchicine and anti-tnf drugs. ...Read more

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Familial mediterranean fever: is it possible for the basic defect be treated?

No: This is a genetic disease caused in most cases by deficiency in pyrin. Replacing the protein won't help as it's needed only in certain areas where neutrophils have begun to congregate. Thankfully, if you're complaint with medication even when you feel well, you can usually avoid the horrible late consequence of the disease -- amyloidosis. ...Read more

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Is there any relations between otoimmune disease and familial mediterranean fever?

Is there any relations between otoimmune disease and familial mediterranean fever?

No, but...: They mimic each other, since both are prone to cause serositis unexpectedly. The most important thing to know about fmf -- if you actually have it -- is to comply with your treatment even if you do not feel sick. It will make you much less likely to get amyloidosis, which is a miserable way to go. Best wishes. ...Read more

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What chromosome does the familial mediterranean fever relate to?

What chromosome does the familial mediterranean fever relate to?

Chromosome 16: The mefv gene is located on the short (p) arm of chromosome 16 at position 13.3, from base pair 3, 292, 027 to 3, 306, 626 (per wikipedia). ...Read more

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Familial mediterranean fever: is getting pregnancy ok?

Familial mediterranean fever: is getting pregnancy ok?

Yes: Because fmf is a relatively rare condition there are few studies of large numbers to answer this really well. Colchicine is used for symptom control in fmf. Data suggest now real difference in pregnancy outcome in treated vs untreated groups, but treatment helps with symptoms. Genetic testing for offspring is recommended. Increased infertility rates and miscarriages (~25%) with this disease. ...Read more

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Familial mediterranean fever. Should I be getting pregnancy?

Familial mediterranean fever. Should I be getting pregnancy?

Fever: Familial mediateranean fever may result in infertility, abortion and medications taken for familila mediterranean fever may have side effects on fetus therefore it is important to go the physician and discuss with your physician. ...Read more

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Any link between familial mediterranean fever and getting pregnant?

No: Fmf is more a gastrointestinal inflammatory disease, usually hereditary. I have several patients with fmf who have been successfully pregnant as long as the disease is under control. ...Read more

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Familial mediterranean fever: can the cause be treated?

Familial mediterranean fever: can the cause be treated?

See an internist: Or a geneticist. There are specialized dna testing techniques which can assist with this. But first, before spending a great deal of money, make sure you have had intermittent episodes of self-remitting fevers, belong to one of the ethnic groups in which this occurs, and have no other source for your symptoms. This is an uncommon condition. See a good internist. ...Read more

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Any tips to someone with "familial mediterranean fever"?

Any tips to someone with "familial mediterranean fever"?

Off and on attacks: Signs and symptoms of familial mediterranean fever usually begin during childhood. In fact, 90 percent of all people initially diagnosed with fmf are younger than 20 years old. The signs and symptoms, which are collectively referred to as attacks, often occur with little warning. Generally, the attacks last two to three days. ...Read more

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Who diagnoses the familial mediterranean fever and when?

Who diagnoses the familial mediterranean fever and when?

An internist: Or a geneticist. There are specialized dna testing techniques which can assist with this. But first, before spending a great deal of money, make sure you have had intermittent episodes of self-remitting fevers, belong to one of the ethnic groups in which this occurs, and have no other source for your symptoms. This is an uncommon condition. See a good internist. ...Read more

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If familial mediterranean fever is untreated can it cause death?

If familial mediterranean fever is untreated can it cause death?

Not directly: Fmf does not cause death directly (like say for example cancer or coronary artery disease). Patients with fmf do have higher rates of related diseases however, such as nephrotic syndrome or amyloidosis (also subfertility and miscarriages). These other diseases can all contribute to earlier death if the fmf is not treated regularly. ...Read more

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What is the definition or description of: familial mediterranean fever?

What is the definition or description of: familial mediterranean fever?

MEDITERRANEAN FEVER: Familial mediterranean fever, also called familial paroxysmal or recurrent polyserositis is an inherited condition characterized by transient recurring attacks of abdominal pain, fever, pleurisy (chest pain), arthritis, and rash. The condition is asymptomatic between attacks. ...Read more

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Which chromosome does the familial mediterranean fever occur on?

Two genes: More than one type of gene defect can cause familial mediterranean fever. Two common defective genes are
mefv and saa1, and are located on short arms of chromosome 16 and 11 respectively. See this site for more info.
http://ghr. Nlm. Nih. Gov/condition/familial-mediterranean-fever. ...Read more

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What is familial Mediterranean fever? Is it genetic?

What is familial Mediterranean fever? Is it genetic?

Genetic - yes: This is a genetic illness that is inflammatory and causes a variety of symptoms with a fever and attacks of abdomenal pain, joint attacks, chest pain, muscle aches, skin rashes. Your physicians can help clarify how it affects you. ...Read more

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What is familial Mediterranean fever? Is it genetic?

What is familial Mediterranean fever? Is it genetic?

See below: FMF is one of a group of recessively inherited diseases that is characterized by episodes of fever, very painful arthritis, pleuritis with chest pain, serositis with abdominal pain, red inflamed skin lesions, and sometimes amyloidosis. It occurs in Armenians, Arabs, Turks and some Semitic people. It is well controlled by colchicine which also prevents amyloidosis. ...Read more

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What to do if I have familial mediterranean fever and taking colchicine, 1mg. Recently discovered coronary calcium builtup?

See Cardiologist: Familial Mediterranean Fever is treated effectively in most patients with colchicine. Colchicine is not involved in calcium deposits in the coronary arteries. Suggest to see a Cardiologist regarding cause, importance and possible treatment. You undoubtedly have had arthritis with this and the treatment is appropriate. ...Read more

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Is there any cure to familial mediterranean fever?

Is there any cure to familial mediterranean fever?

See below: At present, there are no cures, but management is available with a medicine called colchicine. See your doctor for more info. ...Read more

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Could you explain what is familial mediterranean fever?

Inherited disorder: It is an inherited disorder causing fever and pain and swelling at multiple sites. There is no cure but symptoms can be controlled. See this site for more info.
http://www. Mayoclinic. Com/health/familial-mediterranean-fever/ds00766. ...Read more

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I want to know what's the familial mediterranean fever?

Serious illness: This is a genetic defect in pyrin, which is a protein left behind by angry neutrophils that go to a scene of acute injury to let the other neutrophils know they can maybe stay behind. Inflammatory responses are exaggerated. Most serious is a tendency to late amyloidosis which is horrible. If you're diagnosed comply with your medical regimen scrupulously. Best wishes. ...Read more

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Is it possible that familial mediterranean fever be detected before its symptoms appear?

Yes: Genetic tests can detect susceptibility to familal mediterranean fever though there is a risk of false negatives. See this site for more info.

http://www. Mayoclinic. Com/health/familial-mediterranean-fever/ds00766/dsection=tests-and-diagnosis. ...Read more

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About familial mediterranean fever‏my greetings to youi want to ask about fmf as I made amyloid a (saa) and the result was 41 and the doctor diag?

Misunderstanding?: Tricky call. Serum amyloid-associated protein levels won't establish a diagnosis of familial mediterranean fever; today you want a geneticist or genetics lab to do this for you. It's an important diagnosis not to miss or to make in error; lifelong rx will make the fatal complication of amylodosis less likely, while an erroneous diagnosis results in lifelong unnecessary rx. Be proactive. ...Read more

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I have familial mediterranean fever and I am on colchicine I noticed that every time my period ends I get the fmf is that normal? What's threlation?

I read it's common: Fmf attacks are triggered by the complex hormonal system of our bodies, a chaotic system that defies full analysis. From my reading, maybe 15% of women get an attack with each period. Whether you want to up your rx at this time is between you and your physician. Compliance with your prescription is important to prevent deadly amyloidosis as a complication -- but you know that. Stay proactive. ...Read more

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What is familial mediterranean fever?

What is familial mediterranean fever?

A great mimic: This is a hereditary deficiency in pyrin, which is the brakes on the acute inflammatory response. Episodes of pain in one place -- one side of the chest, the abdomen, a joint, etc -- are accompanied by fever. It seems mild, but especially untreated, tends to produce amyloidosis which is first crippling and then lethal. A few genetic diseases are similar, and fmf often takes years to diagnose. ...Read more

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What is familial mediterranean fever like?

What is familial mediterranean fever like?

Subtle: Brief episodes of fever, generally beginning in childhood, with discomfort in different parts of the body (one side of the chest, the abdomen, a joint, maybe elsewhere) each time. Worse, especially if untreated, the disease often eventually causes amyloidosis, which will first ruin your life, then end it. Genetic testing clinches the diagnosis. Good luck. ...Read more

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What is this familial mediterranean fever?

Genetic disorder: Recurrent periods of fever seen in certain ethnic groups, with attendant complications. See an internist. ...Read more

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