Top
20
Doctor insights on: Alternative Chemotherapy Colon Cancer

Share
1

1
Colon cancer chemo necessary?

Colon cancer chemo necessary?

Depends on stage: Chemotherapy is never used for stage 1 cancers (early). It is sometimes used in stage 2 cancers (early but more advanced than stage 1). Chemotherapy is definitely beneficial in stage 3 cancers (locally advanced) and in stage 4 cancers (distant spread). ...Read more

See 2 more doctor answers
Dr. Barry Rosen
4,368 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


2

2
Is metastatic colon cancer curable?

Is metastatic colon cancer curable?

Possible: But less than 20% survive 5 years. Depends on where the metastases are and how numerous and size. Solitary liver mets without evidence elsewhere in the body can be cured with a liver resection. Diffuse mets to numerous body parts rarelyare curable. ...Read more

See 1 more doctor answer
3

3
Dysphagia and chemotherapy for colon cancer?

Dysphagia and chemotherapy for colon cancer?

It depends ... : Dysphagia is a common side effect with many chemo therapeutic regimens. Some treatments can decrease a patient's ability to fight off fungal and bacterial overgrowth in the mouth and digestive systems. The diagnosis of this isn't usually difficult and can in many cases be treated with medications. ...Read more

See 1 more doctor answer
4

4
Is metastic colon cancer spread to liver treatable?

Is metastic colon cancer spread to liver treatable?

Yes: NOT "curable" but definitely treatable...Direct perfusion anti-neoplastic drugs for one approach and possible immune therapy on the "horizon" ...A positive attitude is necessary and helpful.. METASTATIC .CANCER IS A CHRONIC DISEASE! ...Read more

5

5
Are there any alternatives to chemotherapy treatment for metastic colon cancer?

Yes: While chemo like FOLFOX is transiently effective, more immunotherapeutic agents are showing good responses. Avastin (bevacizumab) a vascular endothelial growth factor inhibitor and Erbitux effecting epidermal growth factor 1 are working well as is the newer Neo-102 against the immunogenic protein. Chemo in conjuction with the biologics (immunochemo) is the best combo. ...Read more

6

6
Which chemo therapy is most effective for KRAS mutant metastic colon cancer ?

Which chemo therapy is most effective for KRAS mutant metastic colon cancer ?

Same drugs as other: Same chemotherapy drugs are used for treating both types of colon cancer. The only difference is lack of benefit from EGFR inhibitors(Cetuximab and Panitumumab). Avastin (bevacizumab) also works in both types. I trust that you know there are 3 chemo drugs that are widely used(5FU or Capecitabine, Irinotecan and Oxaliplatin) ...Read more

7

7
Is colon cancer curable?

Yes: Yes. Many people are cured with colon cancer. If found early surgery alone may be curable. If more advanced (eg, lymph node involvement or metastatic = spread to areas outside of colon), then chemotherapy may be needed. While less likely, even a few % of people with metastatic colon ca may be cured. ...Read more

See 2 more doctor answers
8

8
What is prognosis With chemotherapy for metastic colon Cancer ?

What is prognosis With chemotherapy for metastic colon
Cancer ?

So many variables: Too many variables to give you a pertinent answer. Consult your oncologist to help you with clinical decisions ...Read more

9

9
Any advancements for stage 4 colon cancer treatment?

Any advancements for stage 4 colon cancer treatment?

Immunochemotherapy: When FOLFOX therapy (chemotherapy) has failed Immune reactive agents i.e. Avastin for blood vessel growth and Erbitux for epidermal growth factor have been applied as well as agents affecting tyrosine kinase. The Immunogenic protein that acts as a vaccine isolated, a is a byproduct of oncofetal protein MUC5ac in its post translational form. In stage IV used to produce mAbs for strong ADCC. ...Read more

10

10
Ihow effective are uft chemotherapy pills for metastic colon cancer ?

Ihow effective are uft chemotherapy pills for metastic colon cancer ?

Modestly effective: Fluoropyrimidines (5-FU, Capecitabine and UFT) as a class have modest activity and one of these 3 needs to be combined with Oxaliplatin and or Irinotecan to achieve best results ,as combination chemo is far superior in efficacy than any single chemo drug ...Read more

11

11
Hepatocellular carcinoma.All spleen and partial liver resection.Later,secondary systemic cancer metastasis.any targeted therapy or immunotherapy?

Hepatocellular carcinoma.All spleen and partial liver resection.Later,secondary systemic cancer metastasis.any targeted therapy or immunotherapy?

Yes, for both: Hepatocellular Carcinoma is commonly treated with Sorafenib which is a type of targeted therapy. This is a good choice of treatment in case you have not yet received this drug. Immunotherapy using PD-1 inhibitors has also shown some modest evidence of benefit although it is not yet FDA approved for this indication. Ask your oncologist to guide your treatment further. ...Read more

12

12
How effective r chemotherapy uft pills in metastic colon cancer?

Some response: meds like Xeloda have some tempoary benefit suppressing DNA function as an oral 5FU (fluorouracil). Long term responses are not seen requiring combination therapy to give an optimjum response. Eventually if cancer does show a good response, malignant stem cells will repopulate the site of the original metastasis. ...Read more

13

13
Is folfiri alone effective for metastic colon cancer than irinotecan alone ?

Is folfiri alone effective for metastic colon cancer than irinotecan alone ?

Two drugs vs one dru: Folfiri contains two drugs in the combination: 5-FY(Folinic acid) and Irinotecan. This combination is more effective than using irinotecan alone. It is often combined with Avastin (bevacizumab) in case it is being used to treat colon cancer. ...Read more

Dr. Craig Lum Dr. Lum
1 doctor agreed:
14

14
What can prognosis b like for metastic colon cancer that chemotherapy oxyplatin and raltitrexed ?

Dr. Craig Lum Dr. Lum
1 doctor agreed:

Colon mets: Not having your chart and you in front of me makes it very hard to give you an accurate idea on prognosis. When chemo is started, that means your CA cells have gone beyond the boundaries which would have made txing it simple. The simpler the tx, the better the prgns. The harder the tx, the worse the prgns. On a positive note, f/u with your docs, stay faithful, and you might get a pleasant surprise ...Read more

15

15
Chemotherpay failed , irinotecan and oxyplatin in metastic colon cancer . Liver and peritoneal mets . Is there anything else ?

Chemotherpay failed , irinotecan and oxyplatin in metastic colon cancer . Liver and peritoneal mets . Is there anything else ?

Sorry to: hear that. Discuss with your Oncologist what is the next step. Get family and spiritual support as well. Good luck ...Read more

16

16
Treatments for prostate cancer with bone metastasis?

Treatments for prostate cancer with bone metastasis?

Many: The first line of treatment for this is androgen deprivation. In addition, there are medicines which reduce the risk of fractures with Denosumab showing the most efficacy compared to zoledronic acid, however with some risk of significant side effects. For more extensive disease, a newer IV radium therapy has shown improved survival. Localized radiation can be effective for painful foci. ...Read more

See 1 more doctor answer
17

17
Prostate cancer treatment?

Prostate cancer treatment?

First question: Is whether treatment is necessary, depends on gleason score and psa. Treatment may not add value to you. Watchful waiting follows your psa #, rate of rise. If your gl >/= 7, psa > 10ng/ml, best option is radiotherapy, +/- anti-hormone. Get a few opinions. Do not act in haste. ...Read more

See 2 more doctor answers
18

18
How effective is regorafenib for colon cancer mets?

How effective is regorafenib for colon cancer mets?

Depends: One study showed a response rate of 40%. "Response" in this context, means the tumor shrunk. It is rare for tumors to disappear on regorafenib. Clinical benefit depends to a great extent on the overall fitness of the patient (performance status), extent of disease, and number of prior therapies. Courage and faith, Marilyn994, and my best wishes for you. ...Read more

See 1 more doctor answer
19

19
How effective is the FOLFIRI chemotherapy regimen for treating colon cancer?

How effective is the FOLFIRI chemotherapy regimen for treating colon cancer?

Some effect: Single drug chemotherapy has failed to produce significant improvement in colorectal Ca. Combination chemo as in FOLFIRI with irinotecan has added about 5 month prolongation in survival and with immunotherapy using Avastin (bevacizumab) or Erbitux an additional 2-3 months can be observed. Chemo-Immuno with a mAb targeting the immunogenic protein appears to be giving further enhancement. ...Read more

20

20
Is herceptin (trastuzumab) effective in treating bowel cancer?

No: There is no evidence that Herceptin (trastuzumab) is useful in treating colon cancer. It' s use has been expanded to patients with metastatic esophageal and stomach cancers who over express the her2 protein ...Read more

Dr. Steven Griggs
13 doctors shared insights

Colon (Definition)

The colon is another term for the large intestine. This is the final portion of the digestive system, responsible for absorbing water and storing stool before evacuation. It is divided into sections described as cecum; ascending, transverse, descending and ...Read more


Dr. Steven Griggs
12 doctors shared insights

Colonic (Definition)

This is a combining term referring to some condition, treatment or disease of the colon. Such as colonic enema, colonic ...Read more