Doctor insights on:
Enzyme : Alpha-1-antitrypsin is an enzyme that turns off another enzyme that breaks down elastic tissue. Deficiency can result in severe and premature emphysema especially when combined with smoking or dust exposure. Liver damage canals be a consequence. There are simple tests to check your level. It is an inherited disease and runs in some families. ...Read more
Antitrypsin: Alpha-1 antitrypsin is a normal blood protein that keeps some of the products of your neutrophils from harming your tissues more than they need to. If you're seriously deficient, you'll develop emphysema in midlife, and at some time in your life may develop serious liver function problems. One serious pitfall is assaying the levels during concurrent illness; they may be misleading. Good luck. ...Read more
Depends!: Listed as an uncommon side-effect, but usually not. Coming off them is more likely, since the drugs decrease sympathetic nervous system activity. So if you mean "rebound" in stopping, yes! ...Read more
Alpha-1 is MZ 107.9mg/dl(20.7uM)
Mildly Deficient , should begin infusion or not? It is once a week /lifetime
Chemo: Yes.Get a more detailed answer ›
Liver or lung?: most good pulmonologists and hepatologists would certainly be well versed in what is admittedly a rare disease. If you're not finding it to be the case near where you are, i'd call the nearest academic medical center. If your issues are even more unique, they could also refer you to the most specialized centers across the country. best of luck. ...Read more
In an spep why is reg albumin ok and the % low? Alpha 1 % high and just beta high? Inflammatory ? The% confuses me.
Doez Prazosin cross the BBB and work in the CNS? Ive read conflicting things on pubmed and elsewhere. Does any alpha-1 blocker cross the BBB?
You must be reading: about its use as it treats nightmares in the brain. So yes, it clearly crosses the BBB and clearly WORKS. I treat many people with PTSD and nightmares from war vets to civilians, rape victims, assault, other abuse victims who have terrible nightmares and it practically clears everything up inside of 1 week or 2. Problems are lowered blood pressure, allergic reactions, and, first dose syncope. ...Read more
Diagnosis of AAT def: Alpha-1-antitrypsin is a protease inhibitor of the enzyme elastase. Deficiency can result in disease of the lung, liver, and skin. The serum level is quantified in the diagnosis of aat deficiency. If the aat serum level is greater than 80 mg/dl, it is unlikely that the patient has clinically significant aat deficiency. ...Read more
No: It may be mild or severe. You're born with it, you are likely to become short of breath in middle age (hopefully you are a non-smoker), and the liver disease may come on at any time in your life, or never. ...Read more