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Doctor insights on: Alpha Galactosidase

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What is alpha 1 antitrypsin deficiency?

What is alpha 1 antitrypsin deficiency?

Genetic disease: It's quite variable in severity. The lack of the helpful antitrypsin protein in the blood prevents the neutralization of enzymes from white cells that tend to decrease the elasticity of the lungs. The enzyme itself accumulates in the liver which can't get it into the circulation and this can ruin the liver. This can happen at any age and no one knows why it varies so much; or the liver may be fine. ...Read more

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Can alpha thalassemia be dominant?

Can alpha thalassemia be dominant?

Not quite: People normally have 4 Alpha globulin genes. A mutation in 1, 2, 3, or all 4 genes leads to the 4 levels of Alpha thalassemia. The genetics of the disorder is not all-or-none, not dominant-recessive. Instead, the more mutations, the worse the disease. One mutation = silent carrier (no symptoms), 2 muta. = Alpha trait (mild symptoms), 3 muta. = HGB h (moderate symptoms), 4 muta. = bart's (deaths). ...Read more

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Is cdp choline, magnesium, acetyl L-carnitine and lipoic acid MAO inhibitors?

Is cdp choline, magnesium, acetyl L-carnitine and lipoic acid MAO inhibitors?

NO: In general, MAO inhibitors refer to specific prescription antidepressant drugs & are highly regulated. Many foods & herbs have mild MAO inhibiting actions, such as carrots, chocolate, coffee, ginger, grape & onions,but these effects are not clinically significant & they don't need to be avoided if on a med that interacts with MAO inhibitors: http://www.botanical-online.com/english/vegetalmaois.htm ...Read more

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List alpha lipoic acid capsules ?

List alpha lipoic acid capsules ?

List?: I'm not sure what you mean by your question? There are all kinds of lipoic acid capsules, made by many different companies. For a good review of some that are independently tested, check https://www.Consumerlab.Com/reviews/alpha-lipoic_acid_supplements/alphalipoic/ you may need to subscribe, but $33/year is worth it since you get reviews of many products, not just this one. Good luck. ...Read more

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Compare vitamin E d-alpha tocopheryl acetate vs d-alpha tocopherol?

Compare vitamin E d-alpha tocopheryl acetate vs d-alpha tocopherol?

Not sure: The only distinction I am aware of is the difference between dl-alpha tocopherol and d-alpha-tocopherol. I always remeber the best one this way dl = "darn lousy". This is claimed due to supposed poor absorption of the dl form. ...Read more

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Does alpha thalassemia trait have gene therapy available?

Does alpha thalassemia trait have gene therapy available?

No: Alpha thalassemia trait only causes mild anemia, and the person usually has no symptoms. Gene therapy is not available and would not be needed. ...Read more

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Does alpha thalassemia causes leukemia?

Does alpha thalassemia causes leukemia?

No: Alpha and beta thalassemia have not been reported to cause leukemia, which is cancer of the white blood cells. There is a study of beta thal. Major & intermedia patients in iran, where researchers found 5 leukemia cases in about 4, 600 patients. That is a higher rate of leukemia than in the general population there, but details were unavailable as to what other factors were present in the patients. ...Read more

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Substrate name for lipase enzyme?

Substrate name for lipase enzyme?

Olive oil: At least that's what we used for assays when i was doing a lot of clinical chemistry. Today kitmakers sell you "lipase substrate" which the physician need only do quality control on. I suspect it's olive oil. ...Read more

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Is alpha thalassemia trait the same thing as alpha thalassemia?

Not quite: Normal people have 4 Alpha globulin genes. Mutations in 1, 2, 3, or all 4 of the genes cause the 4 levels of Alpha thalassemia. One mutation = silent carrier (no symptoms), 2 mutat. = Alpha trait (mild anemia), 3 mutat. = HGB h disease (anemia sometimes needing transfusions), 4 mutat. = bart's disease (fatal before birth in almost all cases; lifelong transfusions needed to survive if born alive). ...Read more

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Can an alpha thalassemia carrier marry a beta thalassemia carrier?

Can an alpha thalassemia carrier marry a beta thalassemia carrier?

Of course you can: A person can marry anyone they like. From a thalassemia perspective, and assuming your Alpha thal trait is in cis, your child has a 50/50 chance of being Alpha thal trait vs. Normal and a 50/50 chance of being beta thal trait vs. Normal. Given there is consideration of inheriting two distinct trait states, it would be prudent to sit with a genetic counselor to understand the implications clearly. ...Read more

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Is coreg (carvedilol) an alpha beta blocker?

Is coreg (carvedilol) an alpha beta blocker?

Yes: Carvedilol is an excellent medication that has Alpha & beta blocking properties. ...Read more

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M spike in.Urinie protine alpha 2?

M spike in.Urinie protine alpha 2?

An M spike in either: The urine or the serum reflects the production of a single (monoclonal) globulin. It is found in multiple myeloma, a malignancy of the plasma cells that make antibody, and also can be found in so-called monoclonal gammopathy of unclear significance (mgus) which is generally benign. ...Read more

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Probiotics gives lactobacillus acidophillus & bifidobacterium. Whey: beta lactoglobulin & alpha lactalbumin. Can both provide similar benefits?

Probiotics gives lactobacillus acidophillus & bifidobacterium. Whey: beta lactoglobulin & alpha lactalbumin. Can both provide similar benefits?

No: Probiotics and whey provide different benefits. They both have "lacto" in their names, which may be the source of your confusion. Lacto means related to milk. Lactobacillus is a bacteria that can grow in dairy products. Whey is the thin, clear liquid that is left when milk has curdled; it is high in protein. Probiotics are good for intestinal health. Whey is primarily a protein source. ...Read more

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Enzyme inducers & enzyme inhibitors, what are these?

Enzyme inducers & enzyme inhibitors, what are these?

Biochemistry enzymes: One induces and other inhibits action of enzyme. Great Wikipedia question. If you have never heard of it always go there first before coming here. ...Read more

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How was alpha thalassemia named?

Conventional: As scientists investigated hemoglobin, the complicated compound in red blood cells that carries oxygen, they learned that it was made up of 5 parts; 4 of these are 2 copies each of 2 different proteins. They named these Alpha chains and beta chains. If you inherit a condition where the Alpha chains are produced in smaller amounts than normal, you have Alpha thalassemia. ...Read more

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Does taking alpha lipoic acid help menopause?

Does taking alpha lipoic acid help menopause?

No: There are no reputable large double blinded studies on Alpha lipoic acid and menopausal symptoms. ...Read more

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Is pyruvate dehydrogenase deficiency heritable?

Is pyruvate dehydrogenase deficiency heritable?

Yes.: In the most common situation it is inherited in an x-linked pattern, affecting hemizygous males (with one x chromosome) and heterozygous females (two x chromosomes, one with mutation). Less commonly it is inherited in an autosomal recessive pattern, in which a mutation must be provided by both the mother and the father of the affected person. ...Read more

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