Doctor insights on:
Alpha Fetoprotein Testicular Cancer
Mom age 60
ct: large lobulated mixed hypodense masses of 15x10 cm
in toto in right lobe of liver
afp alpha-fetoprotein = 4.46 iu/ml
is cancer or not?
Mom and liver spot: Unfortunately, nothing on a ct, regardless of lab studies like AFP gives a definitive diagnosis. An elevated AFP blood test is seen in about 60% of liver cancer patients. So 40% of patients with liver cancer may have normal AFP levels (less than 10) which do not exclude cancer. The major issue is the mass which must be biopsied to get a diagnosis, after which a plan can be made. ...Read more
Testicular mass: Usually painless. If this is not a cryptorchid testis and the person is not an intersex, it's basically dumb luck. There was a claim on an old retrospective study that physical fitness contributes to risk, but i believe this simply men exaggerating their achievements after losing a testis. Early puberty and lack of exercise are listed as possible risk factors. ...Read moreSee 1 more doctor answer
Usually an adept: Hand examining the scrotum is the beginning, but you are likely referring to Alpha -feto-protein (embryonal and yolk sac tumors) and HCG (human chorionic gonadotropin) choriocarcinoma, germinoma, and teratoma. Seminoma may not produce either, and never afp. These occur in all ages, but especially young men teens and twenties. ...Read moreSee 2 more doctor answers
Find lump on exam: Before you can know, you are concerned about a lump on testicular self exam. Then you go see your doctor who does a complete physical exam and orders some tests. The confirmed diagnosis comes from the pathologist who makes the call by looking at the stained cells from the lump under a microscope. Those cells come from a biopsy of the lump. ?Make an appointment? ...Read moreSee 2 more doctor answers
What does tumour markers (for testicular cancer)mean? Does the cancer have to be wide spread before it shows in the blood?
No: There are three different tumor markers that can be elevated in different types of testicular cancer: beta hcg, afp, and ldh. They can be elevated even when the cancer is only in the testicle and hasn't spread anywhere else in the body. On the other hand, it is also possible to have metastases without elevated markers because some types often don't make any marker at all (eg pure seminoma). ...Read moreSee 2 more doctor answers
It usually does not: Work this way. There is no indication to get these tests unless a mass is suspected, in the testes or a midline abnormality most commonly in a young man. The blood tests, Alpha feto protein and human Chorionic Gonadotropin are indicated to help point the origin of a testis or mediastinal mass. The disease is unusual enough to make these test as routine screening not worthwhile. ...Read moreSee 2 more doctor answers
Some can help..: The diagnosis of testicular cancer requires a tissue biopsy to determine that cancer is present and the specific type. There are some tumor markers for testicular cancer that can be detected in the blood to help determine response to chemotherapy and disease activity. These are not present in all patients with testicular cancer and are not used for the actual diagnosis of the cancer. ...Read moreSee 2 more doctor answers
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