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Doctor insights on: Alpha Fetoprotein Test Results

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What are alpha-fetoprotein tests in pregnancy for?

What are alpha-fetoprotein tests in pregnancy for?

Screening: There are now four tests (quadruple screening) looking for the risks of down's syndrome, trisomy 18 (lethal for babies) as well as neural tube defects such as spina bifida, meningomyelocele and hydrocephalus. ...Read more

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Whats the test for alpha-fetoprotein estriol human chronic gonadotropin inhibin a ?

Whats the test for alpha-fetoprotein estriol human chronic gonadotropin inhibin a ?

Quad Screen: This non-invasive prenatal screening blood (serum) test is done around 12 weeks gestation to see if the fetus may have down's syndrome (trisomy 21) or trisomy 18. It is often combined with a transvaginal ultrasound for better accuracy. This test is not diagnostic. If the screening test is worrisome, then an amniocentesis is usually recommended. ...Read more

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What is the test for: alpha-fetoprotein, estriol. Human chronic gonadotropin, inhibin a ?

What is the test for: alpha-fetoprotein, estriol. Human chronic gonadotropin, inhibin a ?

QUAD screen.: Historically performed between 16-20 weeks, the maternal serum quadruple screen (quad) is likely to fall by the wayside now that cell-free fetal dna can actually be tested from the maternal blood (maternit21 and others). Quad is a screening - not diagnostic - test. ...Read more

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I had an amniotic fluid test which showed a high concentration of alpha-fetoprotein. What does this mean?

I  had an amniotic fluid test which showed a high concentration of alpha-fetoprotein. What does this mean?

AFP in amniotic fl: If an amniocentesis is performed and AFP is detectedin the amniotic fluid, this means that the fetus has an open neural tube defect or an abdominal wall defect. Sonographic evaluation needs to confirm the abnormality. ...Read more

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When did alpha fetoprotein testing start?

When did alpha fetoprotein testing start?

1980's: The Alpha fetoprotein test was around when i was a resident physician. The test has progressed through the y ears such that there are four levels measured in the pregnant woman's blood looking for the risk of down's syndrome (trisomy 21), trisomy 18 & neural tube defects like spina bifida. This is called the quadruple screen best measured between 16 & weeks of pregnancy. ...Read more

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What does a low alpha fetoprotein level mean?

What does a low alpha fetoprotein level mean?

Alphafetoprotein: Very low levels of AFP measured between 16-18 weeks of pregnancy can be associated with chromosomal abnormalities in the fetus, most commonly down's syndrome. Further testing by amniocentesis will rule this out. It may also b a red flag for intrauterine growth restriction and preterm birth. Will need closer observation and testing. ...Read more

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What can cause an elevated alpha fetoprotein level?

What can cause an elevated alpha fetoprotein level?

Different diseases: In pregnancy, elevated alpha fetoprotein levels in a woman's serum can indicate fetal abnormalities, like neural tube defects (spina bifida) or ventral wall defects like omphalocele. Outside pregnancy the levels can be elevated in liver cancer or cancer of the germ cells (ovary, testes). ...Read more

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With cirrhosis what is the relevance of elevated alpha fetoprotein?

With cirrhosis what is the relevance of elevated alpha fetoprotein?

Cancer screen: People with cirrhosis have a higher risk of primary liver cancer. The blood test for alpha-fetoprotein is a marker or screening test for liver cancer. The other method often used is periodic abdominal ultrasound. ...Read more

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Can dehydration cause slightly elevated alpha fetoprotein?

Can dehydration cause slightly elevated alpha fetoprotein?

Dehydration and labs: Dehydration can raise some blood values. Most notably, sodium, chloride, BUN and creatinine are elevated due to less water in the blood. Likewise, Alpha fetoprotein can also be elevated and you would have to see how how the elevation is and how the severe the patient's dehydration was at the time the blood sample was taken. Ask the physician who ordered the test for her input. ...Read more

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My female friend has an alpha-fetoprotein (afp) number of 20.91 ng/ml . . . What does this mean?

My female friend has an alpha-fetoprotein (afp) number of 20.91 ng/ml . . . What does this mean?

Is she pregnant?: The AFP concentration in maternal serum rises throughout pregnancy and goes to about 220 ng/ml. There should be ...Read more