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Doctor insights on: Alpha Fetoprotein Normal Range

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When did alpha fetoprotein testing start?

When did alpha fetoprotein testing start?

1980's: The Alpha fetoprotein test was around when i was a resident physician. The test has progressed through the y ears such that there are four levels measured in the pregnant woman's blood looking for the risk of down's syndrome (trisomy 21), trisomy 18 & neural tube defects like spina bifida. This is called the quadruple screen best measured between 16 & weeks of pregnancy. ...Read more

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What does a low alpha fetoprotein level mean?

What does a low alpha fetoprotein level mean?

Alphafetoprotein: Very low levels of AFP measured between 16-18 weeks of pregnancy can be associated with chromosomal abnormalities in the fetus, most commonly down's syndrome. Further testing by amniocentesis will rule this out. It may also b a red flag for intrauterine growth restriction and preterm birth. Will need closer observation and testing. ...Read more

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What can cause an elevated alpha fetoprotein level?

What can cause an elevated alpha fetoprotein level?

Different diseases: In pregnancy, elevated alpha fetoprotein levels in a woman's serum can indicate fetal abnormalities, like neural tube defects (spina bifida) or ventral wall defects like omphalocele. Outside pregnancy the levels can be elevated in liver cancer or cancer of the germ cells (ovary, testes). ...Read more

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With cirrhosis what is the relevance of elevated alpha fetoprotein?

With cirrhosis what is the relevance of elevated alpha fetoprotein?

Cancer screen: People with cirrhosis have a higher risk of primary liver cancer. The blood test for alpha-fetoprotein is a marker or screening test for liver cancer. The other method often used is periodic abdominal ultrasound. ...Read more

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Can dehydration cause slightly elevated alpha fetoprotein?

Can dehydration cause slightly elevated alpha fetoprotein?

Dehydration and labs: Dehydration can raise some blood values. Most notably, sodium, chloride, BUN and creatinine are elevated due to less water in the blood. Likewise, Alpha fetoprotein can also be elevated and you would have to see how how the elevation is and how the severe the patient's dehydration was at the time the blood sample was taken. Ask the physician who ordered the test for her input. ...Read more

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My female friend has an alpha-fetoprotein (afp) number of 20.91 ng/ml . . . What does this mean?

My female friend has an alpha-fetoprotein (afp) number of 20.91 ng/ml . . . What does this mean?

Is she pregnant?: The AFP concentration in maternal serum rises throughout pregnancy and goes to about 220 ng/ml. There should be ...Read more

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What do you suggest if my female friend has an alpha-fetoprotein (afp) number of 20.91 ng/ml . . .?

What do you suggest if my female friend has an alpha-fetoprotein (afp) number of 20.91 ng/ml . . .?

Pregnant or not?: Alpha-fetoprotein (AFP) is used during pregnancy as part of the "Quad Screen". This is a test that includes AFP and three other blood chemicals to screen for Trisomy 18, Trisomy 21 and Neural Tube defects. If the quad screen is abnormal, a referral to see a perinatologist for a detailed ultrasound and additional testing is in order. AFP can also be tested as part of a cancer work-up. ...Read more

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What's alpha-fetoprotein (afp) in amniotic fluid?

What's alpha-fetoprotein (afp) in amniotic fluid?

See below: AFP is a protein produced by the yolk sac and liver of a fetus. Since it is in the plasma of the fetus, it can be found in the blood of the mother. ...Read more

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What are alpha-fetoprotein tests in pregnancy for?

What are alpha-fetoprotein tests in pregnancy for?

Screening: There are now four tests (quadruple screening) looking for the risks of down's syndrome, trisomy 18 (lethal for babies) as well as neural tube defects such as spina bifida, meningomyelocele and hydrocephalus. ...Read more

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What does an elevated alpha fetoprotein in pregnancy mean?

What does an elevated alpha fetoprotein in pregnancy mean?

Increased tesing: An elevation of the Alpha fetoprotein test should alert your doctor that there may be an increased risk of genetic abnormalities such as down's syndrome in the baby. Pregnant women are offered a more detailed ultrasound test looking for signs of genetic problems & are usually offered an amniocentesis which lets you know the chromosomes of the baby. Down's is also known as trisomy 21. ...Read more