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Doctor insights on: Alpha Fetoprotein Marker

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Marker (Definition)

A "marker" is a protein or enzyme that can represent a disease process. Some markers are specific for a particular disease, while ...Read more


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Increased aldolase, complement c3/c4 serum, sed rate, c-react. Protein, beta globulin, monocytes, bun/creatin low mcv-mch, vit d-possible causes?

Increased aldolase,  complement c3/c4 serum, sed rate, c-react. Protein, beta globulin, monocytes, bun/creatin low mcv-mch, vit d-possible causes?

Complicated: When i was doing clinical medicine, these were collectively sort of the flags for sarcoid disease but I am not saying that's the case here. This is because sarcoid is a diagnosis of exclusion so the advice is to rule out other diseases with additional diagnostic tests which can be done by a primary care physician or rheumatologist. ...Read more

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What does an elevated alpha fetoprotein in pregnancy mean?

What does an elevated alpha fetoprotein in pregnancy mean?

Increased tesing: An elevation of the Alpha fetoprotein test should alert your doctor that there may be an increased risk of genetic abnormalities such as down's syndrome in the baby. Pregnant women are offered a more detailed ultrasound test looking for signs of genetic problems & are usually offered an amniocentesis which lets you know the chromosomes of the baby. Down's is also known as trisomy 21. ...Read more

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What can cause an elevated alpha fetoprotein level?

What can cause an elevated alpha fetoprotein level?

Different diseases: In pregnancy, elevated alpha fetoprotein levels in a woman's serum can indicate fetal abnormalities, like neural tube defects (spina bifida) or ventral wall defects like omphalocele. Outside pregnancy the levels can be elevated in liver cancer or cancer of the germ cells (ovary, testes). ...Read more

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Serum free light chain test shows normal kappa (8.7mg/dl), low lambda (3.80), high kap/lam ratio (2.31). Serum $ urine electrophoresis show no monoclonal protein, nor does serum immunofixation. Likely MGUS, myeloma, or admyloidosis? CBC/met panel ok.

Serum free light chain test shows normal kappa (8.7mg/dl), low lambda (3.80), high kap/lam ratio (2.31). Serum $ urine electrophoresis show no monoclonal protein, nor does serum immunofixation. Likely MGUS, myeloma, or admyloidosis? CBC/met panel ok.

False positive rate: There is 30% or so false positive rate of kappa/lambda ratio in people without MGUS, myeloma or other disorders. For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex. ...Read more

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What does a high alpha 2 protein electrophoresis indicate?

What does a high alpha 2 protein electrophoresis indicate?

Nothing Particular: It is one of those changes which has no clear cut medical implications. You can ignore it and you would not have to think about it or anything serious that I can medically relate it to. Good like ...Read more

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Immunofixation, Serum FAH = Monoclonal IgG kappa immunoglobulin. Beta FAH = 10.5% Abnormal band, immunofixation to follow. I'm IgA deficient too. ??

Immunofixation, Serum FAH = Monoclonal IgG kappa immunoglobulin.   Beta FAH = 10.5% Abnormal band, immunofixation to follow. I'm IgA deficient too. ??

Possibly: If I am understaning this right you have a monoclonal protien band? The most important next steps here would be to identify the band (immunofixation) and then perfrom quantitvaive immunoglobulin levels. IF there is a monoclonal band, you may very well have reciprocal depriciation of alternative immunoglobulins and IgA deficiecny with an IgG monoclonal protein is possible. ...Read more

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What does a low alpha fetoprotein level mean?

What does a low alpha fetoprotein level mean?

Alphafetoprotein: Very low levels of AFP measured between 16-18 weeks of pregnancy can be associated with chromosomal abnormalities in the fetus, most commonly down's syndrome. Further testing by amniocentesis will rule this out. It may also b a red flag for intrauterine growth restriction and preterm birth. Will need closer observation and testing. ...Read more

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Cause of a positive monoclonal T cell beta gene rearrangement?

Cause of a positive monoclonal T cell beta gene rearrangement?

Tumor: Monoclonal proliferation of lymphoid cells is usually an indication of tumor of the lymphoid tissue. ...Read more

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With cirrhosis what is the relevance of elevated alpha fetoprotein?

With cirrhosis what is the relevance of elevated alpha fetoprotein?

Cancer screen: People with cirrhosis have a higher risk of primary liver cancer. The blood test for alpha-fetoprotein is a marker or screening test for liver cancer. The other method often used is periodic abdominal ultrasound. ...Read more

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Total protein 8.3, serum albumin 4.2 , serum globulin 3.8, albumin globulin ratio 1.2.. Is this abnormal?

Total protein 8.3, serum albumin 4.2 , serum globulin 3.8, albumin globulin ratio 1.2.. Is this abnormal?

Abnormal labs: It would be helpful that for the labs mentioned above. If you. Can find the normal range or reference range and list it than our answer can be more educated and helpful. The reference range does vary from one lab to another. ...Read more

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Is alpha2 and alpha 2 macroglobulin the same blood test?

Is alpha2 and alpha 2 macroglobulin the same blood test?

Blood Tests: There are. Few more Alpha 2's in the blood that can be tested. One of those is Alpha2 macro globulin. You doctor should specify what he/she wants done, depending on the diagnosis, so the lab can do the proper tests. ...Read more

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What does a high alpha 1 protein electrophoresis mean?

Inflammation: Serum protein electrophoresis is a test that examines specific proteins in the blood, serum Albumin and alpha-1, alpha-2, beta, and gamma globulins. In the alpha-1 zone, alpha-1 antitrypsin (aat) is the major protein, which is involved in neutralizing enzymes secreted by inflammatory cells. Aat is increased in acute inflammation. ...Read more

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What is acid phosphatase assays test?

What is acid phosphatase assays test?

Max 3.2 ng: Sensitivity of prostatic acid phosphatase is very low 39% of the prostatic carcinomas acid phosphatase level was below the upper limit of normal fixed at 3.2ng. Specificity is high t 96% of cases with abnormally high ri acid phosphatase levels, the diagnosis was adenocarcinoma. In the absence of bone metastases high acid phosphatase level is predictive of lymph node involvement in 90%. ...Read more

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Does alpha thalassemia causes leukemia?

Does alpha thalassemia causes leukemia?

No: Alpha and beta thalassemia have not been reported to cause leukemia, which is cancer of the white blood cells. There is a study of beta thal. Major & intermedia patients in iran, where researchers found 5 leukemia cases in about 4, 600 patients. That is a higher rate of leukemia than in the general population there, but details were unavailable as to what other factors were present in the patients. ...Read more

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What is alpha 1 antitrypsin deficiency?

What is alpha 1 antitrypsin deficiency?

Genetic disease: It's quite variable in severity. The lack of the helpful antitrypsin protein in the blood prevents the neutralization of enzymes from white cells that tend to decrease the elasticity of the lungs. The enzyme itself accumulates in the liver which can't get it into the circulation and this can ruin the liver. This can happen at any age and no one knows why it varies so much; or the liver may be fine. ...Read more

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Blood flow cytmtry shows dual positive cd4cd30 cells absolute count of 2354. IGG slightly elevated with elevated light chains, T cell Beta clone noted?

Blood flow cytmtry shows dual positive cd4cd30 cells absolute count of 2354. IGG slightly elevated with elevated light chains, T cell Beta clone noted?

Asking what?: If your are requesting a diagnosis online, this is not the appropriate venue. Though the flow cytometry results are not totally normal, your results should be reviewed with the physician who ordered it. This format does not give us the ability to determine if your clinical presentation and lab results are consistent with a specific diagnosis. ...Read more

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Can you interpret, squam epi cells few a, alpha 2 protein 1.01 h, possible faint IgM lambda monoclonal protein present, ACE serum 75 h?

Can you interpret, squam epi cells few a, alpha 2 protein 1.01 h, possible faint IgM lambda monoclonal protein present, ACE serum 75 h?

No: Can't interpret random blood test results without context. Talk to the doctor that ordered the tests. Most medical tests (x-rays, blood tests, etc., ) are better at telling us what you don't have rather than diagnosing what (if anything) you do have wrong with you. ...Read more