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Doctor insights on: Alpha Beta Protein Test

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Protein (Definition)

Proteins are large molecules made up of a smaller class of molecules called amino acids. Proteins play an enormous role in the function of our bodies including enzymes, messengers, replicating dna, ...Read more


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Is a IgG quantitative test same as the serum protein electrophoresis test?

Is a IgG quantitative test same as the serum protein electrophoresis test?

Blood tests: They are two different separate blood tests, spep serum protein electrophoresis test is a screening test for plasma cell disorders like mgus, smoldering or full blown myeloma and quantitative igg is a blood test to quantify the amount of igg in blood. Usually more than 3 grams is significant in blood. ...Read more

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Serum free light chain test shows normal kappa (8.7mg/dl), low lambda (3.80), high kap/lam ratio (2.31). Serum $ urine electrophoresis show no monoclonal protein, nor does serum immunofixation. Likely MGUS, myeloma, or admyloidosis? CBC/met panel ok.

Serum free light chain test shows normal kappa (8.7mg/dl), low lambda (3.80), high kap/lam ratio (2.31). Serum $ urine electrophoresis show no monoclonal protein, nor does serum immunofixation. Likely MGUS, myeloma, or admyloidosis? CBC/met panel ok.

False positive rate: There is 30% or so false positive rate of kappa/lambda ratio in people without MGUS, myeloma or other disorders. For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex. ...Read more

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Can you interpret, squam epi cells few a, alpha 2 protein 1.01 h, possible faint IgM lambda monoclonal protein present, ACE serum 75 h?

Can you interpret, squam epi cells few a, alpha 2 protein 1.01 h, possible faint IgM lambda monoclonal protein present, ACE serum 75 h?

No: Can't interpret random blood test results without context. Talk to the doctor that ordered the tests. Most medical tests (x-rays, blood tests, etc., ) are better at telling us what you don't have rather than diagnosing what (if anything) you do have wrong with you. ...Read more

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Increased aldolase, complement c3/c4 serum, sed rate, c-react. Protein, beta globulin, monocytes, bun/creatin low mcv-mch, vit d-possible causes?

Increased aldolase,  complement c3/c4 serum, sed rate, c-react. Protein, beta globulin, monocytes, bun/creatin low mcv-mch, vit d-possible causes?

Complicated: When i was doing clinical medicine, these were collectively sort of the flags for sarcoid disease but I am not saying that's the case here. This is because sarcoid is a diagnosis of exclusion so the advice is to rule out other diseases with additional diagnostic tests which can be done by a primary care physician or rheumatologist. ...Read more

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Does quantitative beta hCG use serum to detect hCG in blood?

Does quantitative beta hCG use serum to detect hCG in blood?

Yes: Serum is the part of blood. It is the liquid part left when blood clots and is centrifuged . Many 'blood' tests, including beta HCG are done on serum. ...Read more

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M spike in.Urinie protine alpha 2?

M spike in.Urinie protine alpha 2?

An M spike in either: The urine or the serum reflects the production of a single (monoclonal) globulin. It is found in multiple myeloma, a malignancy of the plasma cells that make antibody, and also can be found in so-called monoclonal gammopathy of unclear significance (mgus) which is generally benign. ...Read more

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Serum protein electrophoresis - hight beta fraction, what does this mean?

Serum protein electrophoresis - hight beta fraction, what does this mean?

Unimportant: Tell us your values of all proteins. The only two that matter are Albumin and Gamma Globulin. A M spike(monoclonal peak) can be abnormal...so look for this, otherwise you are ok and can ignore the beta fraction. ...Read more

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Had bloodwork and urine test don't know what immunofix electrophoresis gel ( IFE) no Monoclonal proteins&IFE paraprotein urine not detected( MGU) HELP?

Had bloodwork and urine test don't know what immunofix electrophoresis gel ( IFE) no Monoclonal proteins&IFE paraprotein urine not detected( MGU) HELP?

It means: Your tests were essentially negative!!! What was your Doctor evaluating you for?? anemia>> Bone Pain??? Bone abnormalities on scan/xray??? Ask ? again More info please Dr Z ...Read more

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When did alpha fetoprotein testing start?

When did alpha fetoprotein testing start?

1980's: The Alpha fetoprotein test was around when i was a resident physician. The test has progressed through the y ears such that there are four levels measured in the pregnant woman's blood looking for the risk of down's syndrome (trisomy 21), trisomy 18 & neural tube defects like spina bifida. This is called the quadruple screen best measured between 16 & weeks of pregnancy. ...Read more

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Beta blockers ok in pregnancy?

Beta blockers ok in pregnancy?

No.: Atenolol has been linked to poor fetal growth, so plain beta blockers (other examples include propranolol, metoprolol) are avoided as much as possible during pregnancy. Consult with a maternal-fetal medicine specialist to explore your options. ...Read more

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Cause of a positive monoclonal T cell beta gene rearrangement?

Cause of a positive monoclonal T cell beta gene rearrangement?

Tumor: Monoclonal proliferation of lymphoid cells is usually an indication of tumor of the lymphoid tissue. ...Read more

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SPEP test: High Alapha1 .27 (.10-.20) High Alpha1% 3.6% (1.4-2.7%) High Gama 1.23 (.6-.1.2) Low Beta 5.9% (6-9%) and IFE tested positive. Cancer?

SPEP test: High Alapha1 .27 (.10-.20) High Alpha1% 3.6% (1.4-2.7%) High Gama 1.23 (.6-.1.2) Low Beta 5.9% (6-9%) and IFE tested positive. Cancer?

Need more info: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, none of the information you provided suggests cancer. Ife was positive for what? For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Drink enough water daily, so that your urine is mostly colorless. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex. Get HPV vaccine. ...Read more

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What does all this mean listed down below? Monoclonal protein see below hi test result lo units ------------------------------------------------------------ monoclonal protein study, random, u albumin 51 % alpha 1-globulin 8 % alpha 2-globulin 10 % bet

What : What this means is that the blood protein levels show that there is no evidence of a blood tumor that is producing monoclonal antibodies, such as multiple myeloma, plasmacytoma, and some types of b-cell lymphoma. This does not rule out multiple other lymphomas and some other tumors. You need to follow up with your physician who can interpret this test in light of your clinical findings. ...Read more

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What does it mean when protein syrum Beta 2 Globulin are high with beta gamma bridging?

Need more info: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, the pattern could be due to liver disease, chronic inflammation in the intestine or neoplastic proliferation of plasma cells. Discuss it with the doctor who ordered the test. ...Read more

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Immunofixation, Serum FAH = Monoclonal IgG kappa immunoglobulin. Beta FAH = 10.5% Abnormal band, immunofixation to follow. I'm IgA deficient too. ??

Immunofixation, Serum FAH = Monoclonal IgG kappa immunoglobulin.   Beta FAH = 10.5% Abnormal band, immunofixation to follow. I'm IgA deficient too. ??

Possibly: If I am understaning this right you have a monoclonal protien band? The most important next steps here would be to identify the band (immunofixation) and then perfrom quantitvaive immunoglobulin levels. IF there is a monoclonal band, you may very well have reciprocal depriciation of alternative immunoglobulins and IgA deficiecny with an IgG monoclonal protein is possible. ...Read more

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Is alpha2 and alpha 2 macroglobulin the same blood test?

Is alpha2 and alpha 2 macroglobulin the same blood test?

Blood Tests: There are. Few more Alpha 2's in the blood that can be tested. One of those is Alpha2 macro globulin. You doctor should specify what he/she wants done, depending on the diagnosis, so the lab can do the proper tests. ...Read more

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Serum vs urinary aminoacids. Which test is better?

Serum vs urinary aminoacids. Which test is better?

Why do you ask?: If this is screening for birth defects in a newborn, it's the pediatrician's / public health official's call. If this is a fishing expedition for real or imagined behavioral / neurologic illness offered by a non-evidence-based lab ("innovative biomarkers"), please be very cautious. ...Read more

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Globulin Test Tot Protein 8.4, albumin 3.5, Alpha 1 0.3, Alpha 2 0.6, Beta 1.6, Gamma 2.3, m spike not observed, Tot Glob 4.9, A/G 0.7. Any concerns?

Globulin Test
Tot Protein 8.4, albumin 3.5, Alpha 1 0.3, Alpha 2 0.6, Beta 1.6, Gamma 2.3, m spike not observed, Tot Glob 4.9, A/G 0.7. Any concerns?

See below: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, elevated gamma globulins suggest chronic inflammation and it needs to be investigated. You may consult this site and discuss the matter with your doctor. https://www.nlm.nih.gov/medlineplus/ency/article/003544.htm ...Read more

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please guide me i got a result in Alpha Feto protein test 109.08 ng/mL . and i was not feeling well. pls tell me what's should i do?


 please guide me i got a result in Alpha Feto protein test 109.08 ng/mL . and i was not feeling well. pls tell me what's should i do?

Alpha fetal Protein: Increases in AFP in pregnancy are related to possible problems with the fetal nervous system. You need advice from an obstetric physician, and continued testing with ultrasound exams to establish a course of action. ...Read more

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What is an alpha feto protein test as it reates to the liver? What is a good score?

What is an alpha feto protein test as it reates to the liver? What is a good score?

A blood test: This test can be found in several diseases. It is elevated in liver disease including hep c, testicular cancer, and diseases in the OB world. We worry when this is over 250 with liver lesions and find that over 500 in a patient with a liver mass is diagnostic of liver cancer. Some specialists will get a baseline in hep c and use it as a tool to help screen for new liver cancer. ...Read more

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High alpha beta protein and baby measuring 16 weeks when I am 17.5 weeks along. Doc said placenta mostly likely not working? Is there still hope?

Alpha fetoprotein?: There is a test that's typically done at 15-20 weeks of alpha-fetoprotein. AFP is made in liver of baby. High levels can signify spina bifida, anencephaly, chromosomal problems, and problems with baby's intestines being outside their abdominal wall. When one of these markers (there are 4 that are done) is elevated, additional ultrasounds are done and amniocentesis is typically offered. ...Read more

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What does all this mean listed down below? Monoclonal protein see below hi test result lo units ------------------------------------------------------------ monoclonal protein study, random, u albumin 51 % alpha 1-globulin 8 % alpha 2-globulin 10 % bet

What : What this means is that the blood protein levels show that there is no evidence of a blood tumor that is producing monoclonal antibodies, such as multiple myeloma, plasmacytoma, and some types of b-cell lymphoma. This does not rule out multiple other lymphomas and some other tumors. You need to follow up with your physician who can interpret this test in light of your clinical findings. ...Read more

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Can you explain my lumbar puncture results - CSF alpha Feto protein 0.555 Beta HCG 0.322(iu/l) I have a pineal tumour. Tested CSF for germ cell.

Can you explain my lumbar puncture results - CSF  alpha Feto protein 0.555 Beta HCG 0.322(iu/l) I have a pineal tumour. Tested CSF for germ cell.

These values are OK: These levels do not look out of ordinary. You need to relate these levels to previous levels of these markers. if they were high before then this test might have some meaning. Your oncologist is your best guide to explain what it all means. ...Read more

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I had normal serum protein electrophoresis. Alpha-1-globulin is 0.25 (0.17 - 0.50 g/dl). Low end of normal? Do i need to test for alpha1-antitrypsin?

No: Don't bother. What would you do with a result? I'm going to assume that you are a non-smoker and that at age 31 your exercise tolerance is like your peers. You're probably not a candidate for pricey, inconvenient replacement. ...Read more

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What do you recommend if I have elevated alpha feto protein question?

What do you recommend if I have elevated alpha feto protein question?

Go for it!: Please submit a clear & specific question about alpha feto proteins. Clarify and re-ask. ...Read more

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What does a high alpha 1 protein electrophoresis mean?

Inflammation: Serum protein electrophoresis is a test that examines specific proteins in the blood, serum Albumin and alpha-1, alpha-2, beta, and gamma globulins. In the alpha-1 zone, alpha-1 antitrypsin (aat) is the major protein, which is involved in neutralizing enzymes secreted by inflammatory cells. Aat is increased in acute inflammation. ...Read more

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What does a high alpha 2 protein electrophoresis indicate?

Nothing Particular: It is one of those changes which has no clear cut medical implications. You can ignore it and you would not have to think about it or anything serious that I can medically relate it to. Good like ...Read more

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Father has hepatitis b his alpha feto protein increase from11767 to26434 iu/ml while taking medicines sorafenib200 , entacavir, daflon500, udiliv300 why?

Father has hepatitis b his alpha feto protein increase from11767 to26434 iu/ml while taking medicines sorafenib200 , entacavir, daflon500, udiliv300 why?

AFP elevation: Given your father's history of chronic hbv infection and elevated afp, he is likely to also have hepatocellular carcinoma. With that high level, this is almost conclusive of malignancy. Suggest to discuss with your physicians in the local area for further care. ...Read more

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Can you interpret, squam epi cells few a, alpha 2 protein 1.01 h, possible faint IgM lambda monoclonal protein present, ACE serum 75 h?

No: Can't interpret random blood test results without context. Talk to the doctor that ordered the tests. Most medical tests (x-rays, blood tests, etc., ) are better at telling us what you don't have rather than diagnosing what (if anything) you do have wrong with you. ...Read more

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I just had some lab work done. What would cause a low serum albumin level, high alpha 1 and 2 and high c-reactive protein and low vit d?

I just had some lab work done. What would cause a low serum albumin level, high alpha 1 and 2 and high c-reactive protein and low vit d?

Likely inflammation: Generally, decreased Albumin and increased globulins are seen in inflammatory conditions, acute or chronic. The fever ; high CRP also support this. Of note, other conditions may cause this including cancer, but still, the most likely explanation is infection/inflammation. A low vitamin d level may be caused by inadequate intake, no sun exposure, absorbtion problem, kidney disease, obesity. ...Read more

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Hi, ive got elevated alpha 2 macro glob, apolipo protein, alt and not immune to hep b reactive to a, chronic hcv and weight loss, muscle loss.. Wrong?

Hi, ive got elevated alpha 2 macro glob, apolipo protein, alt and not immune to hep b reactive to a, chronic hcv and weight loss, muscle loss.. Wrong?

Serious problem: From what you've said you seem to have a serious issue with your liver. Your lucky in that you have hep c. Now we have a cure for that. Unfortunately Gilead charges $1000/day x 90 days. You should see a gastroenterologist right away and discuss your condition. ...Read more

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M spike in.Urinie protine alpha 2?

An M spike in either: The urine or the serum reflects the production of a single (monoclonal) globulin. It is found in multiple myeloma, a malignancy of the plasma cells that make antibody, and also can be found in so-called monoclonal gammopathy of unclear significance (mgus) which is generally benign. ...Read more

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If. Some body have osephgeal varices and. Normal liver function normal alpha protien is normal. And CT scan show mass in liver. Ap and portal or 12m?

If. Some body have osephgeal varices and. Normal liver function normal alpha protien is normal. And CT scan show mass in liver. Ap and portal or 12m?

Complex issue: Cirrhotics should have careful surveillance for the development of hepatoma. Recommend you find a hepatologist whom you trust and follow the appropriate guidelines. ...Read more

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What is a polyclonal gammopathy? Dr did protein serum test, a2, beta, gamma and crp is high. High wbc anc is also high, with tear drop cells 25%

Go to your doctor: you need to have a hematologist review the results. If your doctor ordered these tests, they should review the results with you . ...Read more

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I've had an electrophoresis test done, serum & urine. Results show a spike in the beta and gamma regions. No monoclonal protein. What does this mean? I have proteinuria and fsgs stage 3. I am 50

What is FSGS?: Please do not use abbreviations....They mean different things to different people. Ask your doctor to advise you about any relationship of your electrophoresis report to your underlying problem. I do not think this report is of any consequence or concern. ...Read more

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