Doctor insights on:
Alpha Adrenergic Agonist Side Effects
With which alpha adrenergic blocking drug is less chance of orthostatic hypotension sideeffect than tamsulosin?
Doctor I am asthmatic and hav no dermatits. Cant manage side effects of beta2 agonists..How to counter them?
Dexamethasone: May help! see this...http://www.ncbi.nlm.nih.gov/m/pubmed/9283684/.Get a more detailed answer ›
Fibrate Side Effect: Myotoxicity (muscle damage, rhabdo) is one, especially when used with statins. Liver enzyme elevation is not uncommon. Creatinine (a kidney lab #) elevation may be seen but not necessarily bad; pancreatitis may be seen, extremely rare. Other serious but extremely rare side effects are possible. Generally safe when doctor prescribed & monitored. Muscle aches = stop & call dr asap; + dark urine=>er. ...Read more
Do Dopamine agonists for Restless Leg Syndrome cross the Blood Brain Barrier? If not, why are side effects like psychosis possible?
What do you advise if I've read that salbutamol is a b2 adrenergic receptor agonist but shouldn't it be an antagonist?
Partial agonist: I hope the concept isn't unfamiliar to you. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC473898/ ...Read more
Best to treat cause: It's best to treat the cause of the nasal congestion (allergies, sinus infection, etc.) but for symptomatic relief of the congestion i suggest a steroid nasal spray and oral decongestant if needed. Different steroid nasal sprays may need to be tried to find one that is most effective. ...Read more
Taking 1mg of Tenex (Guanfacine) every night made me somewhat hypersexual. However, taking 2mg several days ago made me impotent. Can someone please explain how alpha-2 agonists cause impotence?
Alpha 1&2 receptors: Try one and one half. It seems that alpha 2 blockade is used in impotence to increase nitric oxide, but it seems you need both alpha 1 and 2 blockade to block vasoconstriction, since alpha 2 also block the release of norepinephrine and that will increase with alpha blockers. http://www.ncbi.nlm.nih.gov/pubmed/10845761 ...Read more
Can beta blocker be taken for prinzmetals angina if an alpha blocker is added, so there isnt any vasospasm potential? Want off my CCB (side effects)
Stopped Milk Thistle + Alpha Lipoic Acid due to side effects, how long before lethargy from it wears off? My energy was great before and now crashing!
I take risperidone. It has cognitive sideffects due to anticholinergic activity. What can I do to treat it? Will Alpha GPC, choline or lecithin help?
Dose of Risperdone: important. See more anticholinergic side effects at doses greater than 1 mg. Parkinsonism above mg. Concomitant use of Ginko may worsen situation. Ginko has not shown to improve long term cogntive issues. One study in China with concomitant use of Risperdal has been completed but results are unavailable at this time. Another study looking at use of Risperdal with Ginko in autism showed no benefit. ...Read more
Lower testosterone: Orchiectomy and lhrh agonist medications are performed to lower the production of testosterone (fuel that promotes prostate cancer growth). Both will cause a man's testosterone to drop typically lower than 50 (normal >300). Will slow prostate cancer growth but not "cure" it. Side-effects of castration include hot-flashes, osteoporosis, diabetes/cardiovascular risks, etc. Discuss with urologist. ...Read moreSee 2 more doctor answers
Can you tell me a receptor site for a particular neurotransmitter, is it considered an agonist or an antagonist?
Is luvox (fluvoxamine) the only ssri that is a sigma agonist...And is that why it is better for anxiety..Explain sigma a sigma agonist?
See Wikipedia : Drugs known to be ?–agonists include cocaine, morphine/diacetylmorphine, opipramol, pcp, fluvoxamine, methamphetamine, dextromethorphan, and the herbal antidepressant berberine. However the exact role of ?–receptors is difficult to establish as many ?–agonists also bind to other targets such as the ?-opioid receptor and the nmda receptor.Recently selective ?–receptor agonists were shown to produceantidepressant effects in mice. Best wishes. ...Read more
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