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Doctor insights on: Alpha 1 Liver

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Anyone with an alpha-1 antitrypsin deficiency with liver problems?

Anyone with an alpha-1 antitrypsin deficiency with liver problems?

Yes: People with the zz phenotype for alpha1antitrypsin can develop early emphysema, as well as liver disease. Although rare, some of the heterozygotes, e.g. Those with the mz phenotype may also develop lung disease and or liver disease. Go to www.Alphaone.Org. ...Read more

Dr. Zahid Niazi
2 doctors shared insights

Liver (Definition)

This organ plays a major role in metabolism and has a number of functions in the body, including glycogen storage, decomposition of red blood cells, plasma protein synthesis, hormone production, and detoxification. It lies below the diaphragm in the abdominal-pelvic region of the abdomen. It produces bile, an alkaline compound which aids in digestion via the emulsification of ...Read more


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Alt 93 bilirubin 1.4 CT diagnosed in july with fatty liver alpha 1 negative all ANA testing was normal. Could this be cirrhosis? Us showed no fat.

Alt 93 bilirubin 1.4 CT diagnosed in july with fatty liver alpha 1 negative all ANA testing was normal. Could this be cirrhosis? Us showed no fat.

More information : Cirrhosis unlikely but we do not have enough information we suggest that your physician should be able to answer your question. A liver biopsy if necessary would answer you question. ...Read more

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My brother has alpha 1 antiitrypsin gene with his liver affected, Awaiting my own results ..what are my odds of having it? Should my kids be tested?

My brother has alpha 1 antiitrypsin gene with his liver affected,  Awaiting my own results ..what are my odds of having it?  Should my kids be tested?

Variable: Alpha 1 antitrypsin disease results (usually) when two unaffected carriers donate their recessive gene to the offspring. With 2 abnormal genes, the medical condition can be expressed. If you share the same parents, you have 3 potential outcomes. Normal,with two normal genes; a carrier with one normal and one abnormal: or you have it but don't know it(unlikely). 2:1 carrier than normal ...Read more

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Does anybody know about alpha-1 antitrypsin deficiency in children with liver problems?

Does anybody know about alpha-1 antitrypsin deficiency in children with liver problems?

Yes: Diagnosis is generally straightforward. It can be difficult to manage and you will need a focused specialist and make initial contact with the transplant people. ...Read more

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Alpha 1 antityricain what is that ? What are systomns

Alpha 1 antityricain what is that ? What are systomns

Antitrypsin: Alpha-1 antitrypsin is a normal blood protein that keeps some of the products of your neutrophils from harming your tissues more than they need to. If you're seriously deficient, you'll develop emphysema in midlife, and at some time in your life may develop serious liver function problems. One serious pitfall is assaying the levels during concurrent illness; they may be misleading. Good luck. ...Read more

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Alpha-1 is MZ 107.9mg/dl(20.7uM) Mildly Deficient , should begin infusion or not? It is once a week /lifetime

Alpha-1 is MZ 107.9mg/dl(20.7uM)
Mildly Deficient , should begin infusion or not? It is once a week /lifetime

Criteria not met: The American Thoracic Society suggests weekly augmentation therapy with human pooled AAT for individuals who have plasma levels of AAT less than 11 ┬Ámol/L and established airflow obstruction, defined as an FEV1. ...Read more

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Any way to find a doctor in my area that's educated on Alpha 1 defency?

Any way to find a doctor in my area that's educated on Alpha 1 defency?

Liver or lung?: most good pulmonologists and hepatologists would certainly be well versed in what is admittedly a rare disease. If you're not finding it to be the case near where you are, i'd call the nearest academic medical center. If your issues are even more unique, they could also refer you to the most specialized centers across the country. best of luck. ...Read more

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In an spep why is reg albumin ok and the % low? Alpha 1 % high and just beta high? Inflammatory ? The% confuses me.

In an spep why is reg albumin ok and the % low? Alpha 1 % high and just beta high? Inflammatory ? The% confuses me.

Many benign causes: Almost any virus or other exposure that provokes your immune system can produce a "defensive " or protective response. Albumin is a useful parameter that indicates your nutritonal status is not the issue. Beta is indicative that your system is protecting itself. ...Read more

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Doez Prazosin cross the BBB and work in the CNS? Ive read conflicting things on pubmed and elsewhere. Does any alpha-1 blocker cross the BBB?

Doez Prazosin cross the BBB and work in the CNS? Ive read conflicting things on pubmed and elsewhere. Does any alpha-1 blocker cross the BBB?

You must be reading: about its use as it treats nightmares in the brain. So yes, it clearly crosses the BBB and clearly WORKS. I treat many people with PTSD and nightmares from war vets to civilians, rape victims, assault, other abuse victims who have terrible nightmares and it practically clears everything up inside of 1 week or 2. Problems are lowered blood pressure, allergic reactions, and, first dose syncope. ...Read more