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Doctor insights on: Alpha 1 Antitrypsin Deficiency Emphysema And Chronic Gastrointestinal Bleeding

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Could there be a connection between alpha 1 antitrypsin deficiency and smoking marijuana?

Could there be a connection between alpha 1 antitrypsin deficiency and smoking marijuana?

Not sure: This is an interesting question as Alpha 1 antitrypsin deficiency is not "caused" by cigarette smoking, but can certainly be aggravated by it. Thus, i think it is safe to say that any smoking may aggravate the symptoms of Alpha 1, but i don't think that there is a direct connection as smoking marijuana does not have primary affect on the enzyme activity. ...Read more

Dr. Lawrence Kessler
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Copd (Definition)

COPD may include chronic bronchitis, emphysema, or both. Chronic bronchitis is the production of increased mucus caused by inflammation. Bronchitis is considered chronic if you cough and produce excess mucus most days for three months in a year, two years in a row. Emphysema is a disease that damages the air sacs and/or the smallest breathing tubes in the lungs. ...Read more


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Could alpha-1 antitrypsin deficiency couse emphysema ?

Could alpha-1 antitrypsin deficiency couse emphysema ?

YES: Alpha one deficiency is highly assosciated with the development of emphysema. ...Read more

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What are the symptoms of alpha 1 antitrypsin deficiency?

What are the symptoms of alpha 1 antitrypsin deficiency?

Emphysema: Aat deficiency affects primarily the lungs, leading to copd, particularly a panacinar emphysema. Symptoms are variable, but usually involve shortness of breath on exertion, cough, or wheezing. It can also affect the liver, causing chronic hepatitis, cirrhosis, and hepatocellular carcinoma. Necrotizing panniculitis is a rare clinical manifestation involving the skin. ...Read more

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What is alpha 1 antitrypsin deficiency?

What is alpha 1 antitrypsin deficiency?

Genetic disease: It's quite variable in severity. The lack of the helpful antitrypsin protein in the blood prevents the neutralization of enzymes from white cells that tend to decrease the elasticity of the lungs. The enzyme itself accumulates in the liver which can't get it into the circulation and this can ruin the liver. This can happen at any age and no one knows why it varies so much; or the liver may be fine. ...Read more

Dr. Le Wang Dr. Wang
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Can pernicious anemia or severe vitamin B12 deficiency cause chronic non-specific duodenitis??

Dr. Le Wang Dr. Wang
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Can pernicious anemia or severe vitamin B12 deficiency cause chronic non-specific duodenitis??

Not clear: No clear evidence for the causal-effect relationship between the two. PA is an autoimmue-mediated destruction of parietal cells in stomach, resuling in impairmnent of B12 absorption. Certainly it is possible that pernicious anemia may co-exist or exacerbate duodenitis via immune process or loss of balance in duodenal fluid, or anemia. But the causal-effect relationship is not well established. ...Read more

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Best diet for someone with Alpha 1 antitrypsins deficiency?

Best diet for someone with Alpha 1 antitrypsins deficiency?

Simply healthy: Hi AMonroe, The good news is that you don't any specific diet restrictions. Aim to stay in a healthy weight range with a BMI of 20-25. Choose fresh foods, eat plenty of vegetables and moderate amounts of fruits. The majority of your nutrient breakdown should be protein and carbs. Fats should be more omega-3s if possible. Stay active, sleep well. Hope this helps. ...Read more

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Tested MS phenotype of alpha 1. diangosis with COPD in my 20s. History of Smoking w/ asthma. Is the alpha 1 playing a major role in my lung disease?

Tested MS phenotype of alpha 1. diangosis with COPD in my 20s. History of Smoking w/ asthma. Is the alpha 1 playing a major role in my lung disease?

Its deficiency, yes: alpha 1 antripsin deficiency does affect the lungs, as the enzyme plays a major role in defending the lung tissues, refrain from smoking and being around smokers, take medicines as prescribed and keep your follow up appointments, goodluck ...Read more

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Chronic anemia 13 yrs. HepC 3+ yrs. Can elevated IGM 417 simply be the Hep c or more likely a more serious blood issue? Anemia treatd IV iron,procrit (epoetin alfa)

Chronic anemia 13 yrs.  HepC 3+ yrs. Can elevated IGM 417 simply be the Hep c or more likely a more serious blood issue? Anemia treatd IV iron,procrit (epoetin alfa)

Get treated: The new medication for Hep C has proven to be effective for most subjects albeit on the expensive side. You need to consult your doctor to get this taken care. In fact, this may lead to resolution of some of your other problems. ...Read more

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Which disease is more fatal: chronic bronchitis or chronic kidney disease (stage 4)?

Which disease is more fatal: chronic bronchitis or chronic kidney disease (stage 4)?

Chronic bronchitis: Well- I came up with the answer because breathing is quintessential for life. Not that kidneys are any less important but your question was what could be more fatal. If you were to ask what could be more debilitating or what could compromise quality of life more-- it has to be CKD stage 4. They are yet to invent dialyzersctgat you could carry in your purse like an inhaler. ...Read more

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Which disease is more fatal: chronic bronchitis or chronic kidney disease (stage 4)?

Which disease is more fatal: chronic bronchitis or chronic kidney disease (stage 4)?

Depends on severity: Neither disease is fatal if they are stable. However, stage 4 kidney disease tends to worsen to stage 5 disease which can be fatal. The worsening bronchitis depends on the cause (for example, common bacterial infection versus TB or not receiving the right antibiotics). Kidney disease is more likely than bronchitis to worsen without good compliance with medicines and diet and is more serious. ...Read more

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Which disease is more fatal: chronic bronchitis or chronic kidney disease (stage 4)?

Which disease is more fatal: chronic bronchitis or chronic kidney disease (stage 4)?

Depend: Both diseases could be fatal depending on patient has other medical conditions or not because it involving two vital organs - lung and kidney. You will die without either one. ...Read more

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Could an early stage small cell lung cancer cause vitamin deficiencies? Thinking around B12, D, K, E.

Could an early stage small cell lung cancer cause vitamin deficiencies?  Thinking around B12, D, K, E.

You are way out!: You have a load of anxiety without any good reason. Just relax and forget that you have cancer. If you had the cancer, it will not remain hidden. But you will go insane thinking about it and worrying about it. I suggest that you adopt a good hobby like a long morning walk daily and get your mind off the subject of Cancer. ...Read more

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Have hep "C" & Cirrosis chronic ystomach aches & esophageal congestion up to throat.Is this due from chronic liver disease or stress?

Have hep "C" & Cirrosis chronic ystomach aches & esophageal congestion up to throat.Is this due from chronic liver disease or stress?

Stress: Both of these may be playing a role, but the cirrhosis is far more important. Hopefully you are seeing a liver expert and having this dealt with expeditiously. ...Read more

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Alpha-1 antitrypsin deficiency. Can this relate to high GGT in liver, breathing heart and lung issues, can it affect medications like ACE inhibitors

Alpha-1 antitrypsin deficiency. Can this relate to high GGT in liver, breathing  heart and lung issues, can it affect medications like ACE inhibitors

ACE: Is produced in the kidneys and lungs. A-1at deficiency affect the lungs and the liver to cause emphysema and cirrhosis. Due to lung problem, the heart can suffer and symptoms could include tachycardia and heart failure due to the emphysema. It also causes chronic cough. From this you can surmise that yes, GGT can be elevated and ace can decrease but kidney can produce enough. ...Read more

Dr. Harish Rao Dr. Rao
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Can severe vitamin deficiencies cause poor lung function and lung inflammation?

Dr. Harish Rao Dr. Rao
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Can severe vitamin deficiencies cause poor lung function and lung inflammation?

Vitamin D: Vitamin d has been associated with poor lung function. Severe vitamin a deficiency can affect the lining of the airways. Most of the other deficiencies generally make you sick. Thiamine deficiency can affect your heart primarily and lungs indirectly. Most of the others do not affect primarily lungs. ...Read more

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Occasional atypical lymphocytes present, & normochromic rbc's, along with LDH of 280 (normal high is 237) and swollen mediastinal lymphnodes, history asthma only, w/ chronic hives, what's this point 2?

Occasional atypical lymphocytes present, & normochromic rbc's, along with LDH of 280 (normal high is 237) and swollen mediastinal lymphnodes, history asthma only, w/ chronic hives, what's this point 2?

Depends: These results can bee found if you are recovering from illness. Since you have a history of asthma with chronic hives, these findings can also be reactive to hypersensitivity. You should be monitored by repeat labs to see if these changes resolve with time. Follow with your PCP. ...Read more

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Dr. K. Mujib Haque
439 doctors shared insights

Gastrointestinal Bleeding (Definition)

A long tube runs from the mouth to the anus. It includes, in order, the mouth, throat, esophagus, stomach, small intestine (duodenum, jejunum, ileus), caecum, the ascending, transverse, descending, and sigmoid colon (or large intestine) and the rectum. The space inside that tube , the lumen, is considered to be outside of the body. When we bleed into that space ...Read more


Dr. Sue Ferranti
498 doctors shared insights

Emphysema (Definition)

One type of chronic obstructive lung disease (COPD) characterized by a loss of lung tissue, causing hyperinflation and increased effort to ...Read more