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Doctor insights on: Alpha 1 Antitrypsin Deficiency Cirrhosis

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Inherited Emphysema (Definition)

Inherited emphysema = alpha-1 antitrypsin deficiency which can destroy lung tissue ...Read more


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Can pernicious anemia or severe vitamin B12 deficiency cause chronic non-specific duodenitis??

Can pernicious anemia or severe vitamin B12 deficiency cause chronic non-specific duodenitis??

Not clear: No clear evidence for the causal-effect relationship between the two. PA is an autoimmue-mediated destruction of parietal cells in stomach, resuling in impairmnent of B12 absorption. Certainly it is possible that pernicious anemia may co-exist or exacerbate duodenitis via immune process or loss of balance in duodenal fluid, or anemia. But the causal-effect relationship is not well established. ...Read more

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Triglycerides 453 hi. Glucose 132H.Bun 26H. Hemoglobin 11.7 low. Hematocrit 37.5 L. Mchc 31.2 L. RDW 15.5 H. MICROALB CREAT 240 H. VitD 22 L. Father60 and Diabetic . Rest of Cbc and othere normal. What could this be?

Triglycerides 453 hi. Glucose 132H.Bun 26H. Hemoglobin 11.7 low. Hematocrit 37.5 L. Mchc 31.2 L. RDW 15.5 H. MICROALB CREAT 240 H. VitD 22 L. Father60 and Diabetic . Rest of Cbc and othere normal. What could this be?

Need good care: You need to be under the care of a competent physician who can keep your diabetes under control and find the cause of your anemia, which i suspect is due to iron deficiency from blood being lose somewhere. We can't solve it here. If you have a specific question, let us know. ...Read more

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IDA? RBC 4.880 HGB 13.70 HCT 45.0 MCV 92.20 MCH 28.10 MCHC 30.40 RDW 14.50 PLT 368 Serum Iron, 178 Ferritin, 10.6 TIBC, 470 UIBC 292 Saturation 38%

IDA? 
RBC 4.880
HGB 13.70
HCT 45.0
MCV 92.20
MCH 28.10
MCHC 30.40
RDW 14.50
PLT 368
Serum Iron, 178
Ferritin, 10.6
TIBC, 470
UIBC  292
Saturation 38%

This looks good: I'm not sure what your question is here, but overall this information regarding your blood counts looks good. You don't look anemic, the platelets that clot your blood are in good levels, and your infection fighting WBC's are at a good level. Have a great evening! ...Read more

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+ Antimitochondrial M2 antibodies w/ 4previous elevated ALP's. Most recent ALP normal. Still suggestive for PBC?

+ Antimitochondrial  M2 antibodies w/ 4previous elevated ALP's. Most recent ALP normal. Still suggestive for PBC?

No: The diagnosis of PBC is made through liver biopsy. The other best tool is the biliruben. Taken together they give a diagnosis and prognosis for survival. As you know PBC is though to be an auto immune disease. ...Read more

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Help me, 59yrf-dercum's disease, lymphedema, ans disorder, heart disease- mi x3, 10+herniated discs, autoimmunity, gastroparesis, duodenitis w nodule?

Help me, 59yrf-dercum's disease, lymphedema, ans disorder, heart disease- mi x3, 10+herniated discs, autoimmunity, gastroparesis, duodenitis w nodule?

Too many issues here: If you do have all these listed problems, you need a good internist to take care of you and guide you further. Health matters get complicated if you truly have more than one or 2 ailments and you need long term care for any such diseases that are chronic in nature. You need a good primary care doctor to guide you for the long term. ...Read more

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For 58+ F, Hb 10.8, RBC 3.66, PCV 34, MCV 94, MCHC 31, WBC 5.4, Pt 1.8, Iron 57, TIBC 255, TSI 22, RC 1.2, Ferritin 83 indicate which type of anemia ?

For 58+ F, Hb 10.8, RBC 3.66, PCV 34, MCV 94, MCHC 31, WBC 5.4, Pt 1.8, Iron 57, TIBC 255, TSI 22, RC 1.2, Ferritin 83 indicate which type of anemia ?

Mild anemia: Assuming you've had no recent bleeding episodes, these findings could be seen in mild/early anemia of chronic disease. Hgb and Hct are only boarder line low, and iron panel appears within the reference range. Even something as simple as a particularly heavy period could cause mild anemia of this type, though. If you have a chronic medical illness, it could cause this type of anemia. ...Read more

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Can lupus cause non-alcoholic fatty liver?

Can lupus cause non-alcoholic fatty liver?

Autoimmune hepatitis: Lupus is associated with autoimmune hepatitis, not nash (non-alcoholic fatty liver). Nash is commonly see in settings of obesity, excessive alcohol intake, diabetes, high cholesterol. Both entities can occur together when respective risk factors for both exist. ...Read more

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Does folic acid deficiency cause irreversible nervous system damage?

Does folic acid deficiency cause irreversible nervous system damage?

Not usually, but : Do you really have Folic Acid deficiency? If so, you could have elevation of homocysteine, which could be a risk of heart attack and/or stroke. If this is the case, have your doc check for an mthfr (tt or ct allele genetic condition), as this could be quite a problem if not addressed. The tt is relatively uncommon, but must be treated. ...Read more

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Describe the treatments enzyme substitution in wilson disease?

Describe the treatments enzyme substitution in wilson disease?

Wilson disease: Excess opper accumulation with serious end organ damage. Treatment after diagnosis is chelation therapy to diseaseexcess copper. Then avoidance of reaccumulation. See mayo clini wilsons disease well written and presented for non medical personnel. ...Read more

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Iron deficiency anemia wid calcium deficiency?

Iron deficiency anemia wid calcium deficiency?

Fe -Ca: Ida is common in young menstruating females. Calcium deficiency? Quite odd at any age. Wonder if your Albumin is normal giving a falsely low calcium.... Why would anyone check a calcium in a healthy 18 yo? Maybe there is more to this story. Maybe you should talk to doc who drew your labs. ...Read more

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Alt elevated (76, 63) after 2 blood tests and increased parenchymal echogenicity on us. Nafld or nash?

Alt elevated (76, 63) after 2 blood tests and increased parenchymal echogenicity on us. Nafld or nash?

Continue workup: Now would be a great time to get really into aerobic fitness -- this is likely to reverse nash / nafld. You'll get checked for hepatitis c, wilson's, hemochromatosis, autoimmune hepatitis and a few others. Trust you're not taking meds or that they have been ruled out as causing the problems. ...Read more

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My blood test results: total bilirubin: 1.41 h ast: 40 h alt: 100 h total alk phosphatase: 43 l serum total protein: 7.1 e.R. Said hepatitis?

My blood test results:
total bilirubin: 1.41 h
ast: 40 h
alt: 100 h
total alk phosphatase: 43 l
serum total protein: 7.1

e.R. Said hepatitis?

Let's try this...: I have only a little bit of the story you've shared. Perhaps it's time to see whether the ast and alt get back to normal after two weeks off alcohol and any not-totally-necessary meds you may be taking. If so, this is the start of a healthier life after alcohol. If not, the workup for virus infections, iron overload, wilson's, autoimmunity & need for exercise can begin. Good luck. ...Read more

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My dad 70 yrs has macrocytic anemia. Hemoglobin 9.5, hematocrit 28. Hematologist gave maltofer pill a day. In a month hemoglobin 10 hematocrit 30?

My dad 70 yrs has macrocytic anemia. Hemoglobin 9.5, hematocrit 28. Hematologist gave maltofer pill a day. In a month hemoglobin 10 hematocrit 30?

What is the question: Please rephrase your question to get a better answer. Please discuss in detail with his hematologist. The fact that hematologist gave the iron- means that your hematologist thinks there is a component of iron deficiency. So, continue iron and f/u with your md. However, it does not fit exactly with macrocytosis. Other work up still needs to be done to see explanation for macrocytosis. ...Read more

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Normocyt, WNL RDW, anemia-hgb 13, rbc 4.3. PO Fe for 1 yr w/ no improvement. Fe 58, ferritin 15, TIBC 347. Asymptomatic. Thoughts on IV iron?

Normocyt, WNL RDW, anemia-hgb 13, rbc 4.3. PO Fe for 1 yr w/ no improvement. Fe 58, ferritin 15, TIBC 347. Asymptomatic. Thoughts on IV iron?

Too aggressive: With the numbers you're presenting I'm not sure who put the idea of doing IV iron into your thought process. Hb-13 for age 74 isn't far off of expected norms for age. If you want to do SOMETHING check thyroids, serum zinc, serum magnesium, & serum Vitamin D. Eat more spinach, beans, dried fruit, seafood, & poultry. Questions? www.healthtap.com/drsaghafi Use Key Code: PDXFNR to make appointment. ...Read more