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Doctor insights on: Allergic Compazine Other Drugs Avoid

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If I am allergic to compazine, (prochlorperazine) are there other drugs I should avoid?

If I am allergic to compazine, (prochlorperazine) are there other drugs I should avoid?

Some similar drugs: Prochlorperazine (compazine) is a phenothiazine type of drug. Other phenothiazine drugs include: Promethazine (phenergan), Chlorpromazine (thorazine), Fluphenazine (prolixin), trifluoperazine (stelazine), etc... A person allergic to Compazine (prochlorperazine) may choose to avoid other drugs of the same type, but it is hard to predict which similar drug he will react to. ...Read more

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Dr. John Landi
49 doctors shared insights

Prochlorperazine (Definition)

Prochlorperazine is an inotrope which is a kind of heart ...Read more


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If I am allergic to Compazine (prochlorperazine) (tongue swelled up 26 years ago!), is it safe to take Hydroxyzine? Always told to be aware of "zine" drugs.

They are not close: in this case, the name does NOT tell you much about the chemical structure of the drug and these two are not very similar and do NOT generally cross react at all. Without an actual examination, I cannot give specific medical advice on your particular health, and you could have reactions to more than one drug regardless of which two drugs we choose, but these two drugs aren't closely related. ...Read more

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Can i take antivert if i'm allergic to compazine (prochlorperazine)?

Can i take antivert if i'm allergic to compazine (prochlorperazine)?

Yes: They are in different drug classes and should not cross react. However they are not usually given for the same indication. If you are looking for a good substitute for nausea a better choice would be zofran and/ or possibly dramamine. Phenergan (promethazine) is very sedating and may not be tolerated but is also a possibility if looking for nausea solution. Antivert is acceptable. ...Read more

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If I'm allergic to compazine (prochlorperazine) can I take Dramamine?

Allergy: Please contact your primary doctor about this. If you are allergic to compazine (prochlorperazine) please stop taking it and listen to your doctor's advice. Hope all goes well. ...Read more

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If i am allergic to compazine can i take phenergan (promethazine)?

If i am allergic to compazine can i take phenergan (promethazine)?

Probably: Compazine causes some people to have weird, extrapyramidal reactions (not an allergy). I think it's a bad drug. Phenergan (promethazine) is much better tolerated by most people. ...Read more

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Im allergic to Compazine, was recently prescribed reglan (metoclopramide) and it gave me the same side affects. Was the dr right in giving me relan?

Im allergic to Compazine, was recently prescribed reglan (metoclopramide) and it gave me the same side affects. Was the dr right in giving me relan?

Probable: You have an idiosyncratic response to these two drugs. The neuromuscular responses may be quite similar but these two drugs do not share similar allergenic or chemical structure. I can't tell you whether it is appropriate for the doctor to prescribe Reglan (metoclopramide) for you not knowing much about your history or previous response to alternate therapy. ...Read more

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How are antipsychaotic drugs like compazine (prochlorperazine) used for sedation and psychosis when they cause akithesia and dystonia? I've seen it make people crazier

How are antipsychaotic drugs like compazine (prochlorperazine) used for sedation and psychosis when they cause akithesia and dystonia? I've seen it make people crazier

Antipsychotics: Every medication has side-effects, and antipsychotics are no exception. If used cautiously ; with clear indications ; close monitoring, they are for the most part safe. ...Read more

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Compazine (Definition)

Prochlorperazine is an inotrope which is a kind of heart ...Read more