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Doctor insights on: All Blast Crisis

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Help please? I want to know what are the clinical features in a patient having cml with blast crisis?

Help please? I want to know what are the clinical features in a patient having cml with blast crisis?

It is like Acute Leu: CML is a chronic leukemia which can transform(Change) into an Acute phase called Blast Crisis. If that happens patient will likely develop symptoms similar to those in acute Leukemia. These may include Fever(repeated infections), bleeding from low platelets and marked weakness, fatigue and often some weight loss. Regular blood count checks(CBC) can easily answer the question that you have raised. ...Read more

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Doctors, what are the clinical features in a patient having cml with blast crisis?

Doctors, what are the clinical features in a patient having cml with blast crisis?

Blast crisis in CML: ... is usually picked up by a blood test or bone marrow biopsy showing increased numbers of immature blast cells, not necessarily by symptoms. It can be accompanied by low numbers of normal RBC (anemia) causing shortness of breath with exercise, or easy bruising from low platelets. The spleen can become enlarged causing abdominal fullness. ...Read more

Dr. Liawaty Ho Dr. Ho
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CML 10/12. Gleevec .5 log at 6 mths. Sprycel (dasatinib) .5 log at 6 mths. Stem cell transplant 4/14. 7/14 Blast crisis - 65% blast BM + Aspergillus F lung Help?

Dr. Liawaty Ho Dr. Ho
1 doctor agreed:
CML 10/12. Gleevec .5 log at 6 mths. Sprycel (dasatinib) .5 log at 6 mths. Stem cell transplant 4/14.  7/14 Blast crisis - 65% blast BM + Aspergillus F lung Help?

Difficult case: it is a complicated case obviously. first and foremost the infection has to be treated. i would suggest you to follow up with ID and oncologist very closely. importantly is to check if there is certain mutation like T315i mutation as this mutation is resistant to gleevec, sprycel, tasigna (nilotinib) - and should be treated with ponatinib or aurora kinase inhibitor etc. discuss with oncologist. God bless ...Read more

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What is oculogyric crisis?

What is oculogyric crisis?

Dyskinesia: It's a type of dyskinesia (movement disorder showing either diminished movement or too much movement, with tics and jerks, etc) involving the muscles of the eye. It's acute, and can be relieved quickly also. It's most commonly seen with medicines that block the neurotransmitter dopamine, such as haldol, stelazine, and thorazine -- but also newer antipsychotics, as well as the GI drug reglan (metoclopramide). ...Read more

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What is midlife crisis for men?

What is midlife crisis for men?

Midlife crisis: This is time when men realize their own mortality & how much time they have left in their life. This can be triggered by changes such as loss or job or financial, etc. ...Read more

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What is a midlife crisis for men?

What is a midlife crisis for men?

Midlife crisis: This is time when men realize their own mortality & how much time they have left in their life. This can be triggered by changes such as loss or job or financial, etc. ...Read more

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What is midlife crisis in women caused by?

What is midlife crisis in women caused by?

Midlife crisis: This is time when men realize their own mortality & how much time they have left in their life. This can be triggered by changes such as loss or job or financial, etc. In women, this occurs commonly in mid 40's. & shows similar symptoms of sadness & remorse & more attention to appearances. ...Read more

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Had a badd experience with crisis services?

Had a badd experience with crisis services?

Question: Is this a comment or question? I'm sorry you had a bad experience. I would call back on monday, ask to speak with a supervisor about your experience. ...Read more

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Can 24 year olds go through a midlife crisis?

Can 24 year olds go through a midlife crisis?

Not really, but...: In each period of life, one can have troubles dealing with the challenges during that period. A primary care doctor can help with such problems. A person can also talk with non-medical people, such as family relatives, friends, clergy, counselors, etc... When such problems happen during the middle of life (age 40-50 years), it can be called a midlife crisis. ...Read more

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How do you help someone going through a midlife crisis?

How do you help someone going through a midlife crisis?

Professional help: Have your friend see a psychologist or psychiatrist to help in making good decisions and understand what they are going through. ...Read more

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Men 101: what is a midlife crisis for women / wives like?

Men 101: what is a midlife crisis for women / wives like?

Midlife crisis: This is time when men realize their own mortality & how much time they have left in their life. This can be triggered by changes such as loss or job or financial, etc. In women, this occurs commonly in mid 40's. & shows similar symptoms of sadness & remorse & more attention to appearances. ...Read more

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In what way can I tell if I am having an addisonian's crisis?

In what way can I tell if I am having an addisonian's crisis?

Well...: If you were having a true Addisonian crisis, you would be in a comma or close to it... You would not be able to type ...Read more

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I want to know if my husband is going through a midlife crisis?

????: What is he doing? It may be a good idea to see a marriage counsellor together.Good luck. ...Read more

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I am actually in crisis right now as I have gone through a lot of grief and loss recently and am in deep despair?

I am actually in crisis right now as I have gone through a lot of grief and loss recently and am in deep despair?

Call crisis line:: Sounds like you feel pretty awful. That is so too bad! There are a lot of people who can help you through this, in the fastest, safest way possible. Since you are in crisis, try this number Suicide & Crisis Hotline 1-800-999-9999, or this one: Suicide Prevention Lifeline 1-800-273-TALK If these folks can't help, call your doc, if you have one, or please go to ER. Help is there for you, call! ...Read more

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I have apologized but she says she is having a midlife crisis and she wants space how long do the side affects last(just a couple weeks)?

I have apologized but she says she is having a midlife crisis and she wants space how long do the side affects last(just a couple weeks)?

Mid life crisis: if possible counseling may be helpful in the adjustment for both of you. You can call during business hour to speak to a psychiatrist on health tap prime. ...Read more

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I have been going through a crisis lately with a break up, all my thoughts gather up and they come consistently and they cause me to freak out. ?

I have been going through a crisis lately with a break up, all my thoughts gather up and they come consistently and they cause me to freak out. ?

Panic attacks: Hi Bobby307,it appears that you are having panic attacks when you have these thought insertions, and this is completely normal under the circumstances. The best way to deal with this is with "talk therapy" with a psychologist, because that will give you the opportunity to to find closure of this event in a supervised and controlled manner thx ...Read more

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Is it normal to lose 10% of body weight when going through an irremediable life crisis that is not indicative of illness either physical or mental?

Is it normal to lose 10% of body weight when going through an irremediable life crisis that is not indicative of illness either physical or mental?

Possible.: Not normal, but possible to lose a large amount of wt secondary to stress. Wt loss that increases progressively or is accompanied by fevers, chills is worrisome. ...Read more

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Due 2 be done with Forteo, but my med conditions don't let me be on many cause of crisis. What would be comparable to Forteo without complications?

Due 2 be done with Forteo, but my med conditions don't let me be on many cause of crisis. What would be comparable to Forteo without complications?

Varies: There are multiple osteoporosis meds from pills, to nasal sprays, injections; they all have a variety of different side affect profiles. Usually with your primary care doctor, you would select the medication that is most likely to be tolerated by you with the most potential benefit. ...Read more