Doctor insights on:
Alkaline Phosphatase Levels In Children
Wrong approach: Alkaline phosphatase is a lab value to tell a physician what is happening, not a medical problem to treat. It can be high just because you're growing (teens tend to be maybe 5x the upper limit of the reference range). About 5% of older folks have a high alk phos for "no reason", presumably paget's of the bone that never becomes evident; nonfasting samples may have it from the intestine. ...Read more
Plenty: You describe yourself as a 73 year old lady and I'm betting you feel well but have an alk phos a bit high on your routine chemical profile. Many folks, depending on blood type, shoot the alk phos up after eating. Maybe 5% of folks your age have a high alk phos because of subclinical paget's disease which we aren't going to treat or worry about. "treat the person, not the labs.". ...Read more
No reason.: There are ranges of "normal" for each blood test done. These may be different from one lab to other, depending on the type testing done and reliability of lab. Also, if a specific test is very abnormal and doesn't make sense clinically to the doc, it's probably lab error: just repeat it. That being said, low levels on many tests are not a problem: alk phosphatase is one. 'fagetabatit'-:). ...Read more
Upper end of normal:
The level is above the upper limit for normal but not by much. All lab results need to be interpreted in the clinical context and you should discuss it with your doctor and see this site for info.
http://www. Nlm. Nih. Gov/medlineplus/ency/article/003470.htm. ...Read more
Normal: No lab value means anything in isolation. Further, assuming the units are IU/mL, this is right in the middle of the reference range. Usually alk phos is part of a panel that's used for health screening. You are probably not a teen in your growth spurt, in the third trimester of pregnancy, a Paget's sufferer, or a person with a liver mass obstructing bile flow. Thanks for asking and best wishes. ...Read more
Bone turnover: Alkaline phosphotase is an indirect measure of bone turnover. Bone remodels like any other living system and this shows how biologically active your skeletal system is. ...Read more
Low alk phos (ALP): Deficiencies in vitamin b6, folic acid, vitamin c, phosphorus, zinc, and protein can lead to low alp as well as an excessive intake of vitamin d. Hypophosphatasia, a rare genetic disorder affecting bone development, can cause low alp. other conditions associated with low alp include cardiac surgery, hypothyroidism, and pernicious anemia. ...Read more
Alkaline phosphatase: No need to do anything, this is not going to cause you any problems. ...Read more
Not concerned: You have stated in your history that you have hepatitis c with known cirrhosis. This may be the cause if is extensive enough to cause obstruction to bile flow in some areas, or several percent of men your have have high alkaline phosphatase from subclinical / harmless paget's of bone, or the specimen being nonfasting. Don't treat a number. Stay proactive. ...Read more
Is a 194 alkaline phosphatase level something that should be investigated? I am a 47 yr Old female
Alkaline phosphate: Elevated alkaline phosphate can be a sign of hyperparathyroid. It is best to talk with your physician and see if this has been slowly elevating over the years along with your Calcium. It is also elevated in other skeletal diseases and liver diseases, but seems to be at higher levels in those diseases. ...Read more
Stop worrying: Unless there is something else obviously wrong, the fact that your alk phos is slightly above the range for most (not all) apparently healthy middle-aged sedentary people shouldn't bother you. You may even still be growing, or might be one of those folks whose alk-phos is up on a non-fasting specimen. ...Read more
Liver disease, etc..: This usually means liver involvement. It can also mean biliary obstruction, pregnancy, and bone diseases. If can be transiently elevated in acute pancreatitis. Other lab values need to be looked at to determine the specific cause. See your doctor to go over the rest of the blood work. ...Read more
My blood work showed a level of 228 for alkaline phosphatase test. Will I need more test? What could it mean?
Yes: An elevated alkaline phosphatase will need to be evaluated with additional blood tests to determine why it is elevated. Most commonly this is due to some form of insult to the liver, usually alcohol. But even a cold can cause an elevated alkaline phosphatase. If your other liver enzymes are elevated, particularly, ggt, your doctor will likely order an ultrasound. ...Read more
What could cause alkaline phosphatase levels to steadily increase over a period of years, now at an elevated level?
Alkaline phosphatase: Causes for elevated Alk phos: biliary obstruction stone, tumor, stricture; autoimmune biliary cirrhosis; liver infiltrates do to granuloma, fatty liver, amyloidosis, sarcoidosis, malignancy; meds like estrogen, chlorpromazine, erythromycin ; viral hepatitis; bone diseases: Paget's, osteomalacia, mets to bone, PTH disease, vitamin d def, fracture ...Read more
Two recent blood tests indicate alkaline phosphatase levels of 150 and 146. All my other blood tests are well within normal. Should I be worried?
There are none: Lab reference ranges are set up so that several percent of healthy folks fall outside on either end. ...Read more
What are the causes of and how can the levels be reduced of serum creatinine, serum alkaline phosphatase?
Elevated ALT levels and alkaline phosphatase direct bilirubin is. 2 not very old only 18 gained about 30 pounds in 3 months what do these test mean?
U R seriously sick: I see you are an 18 year old male taking "provigil", a stimulant prescribed for sleep apnea and narcolepsy and used illicitly to promote wakefulness. It can poison your liver and you need to talk with your physician about this. The fact that you've gotten fat in 3 months is very worrisome. Your doctor must rule hepatitis, hemochromatosis, wilson's, fatty liver and more in or out. ...Read more
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