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Doctor insights on: Alimta Avastin And Carboplatin

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Can Abraxane and Avastin (bevacizumab) be used for treating ovarian cancer?

Can Abraxane and Avastin (bevacizumab) be used for treating ovarian cancer?

Yes it is an option: The standard therapy for ovarian cancer initially is still a taxane (usually Taxol) and Carboplatin. However, Abraxane is an effective taxane down the line for recurrences, and is potentially less toxic. Avastin (bevacizumab) has been combined safely with Abraxane and the two may be helpful for recurrence management. But the question is a bit difficult to answer concretely because circumstances differ. ...Read more

Dr. Brad Goldenberg
49 doctors shared insights

Carboplatin (Definition)

Carboplatin is an aklylating agent which is a ...Read more


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Ciii ovarian cancer in 06, 1212, surgery and chemo paxitaxtel/carboplatin. In remission. Recurrence treated with tamoxifen, carboplatin alone, abraxan, then topotacan to no avail. Which chemo next?

Ciii  ovarian cancer in 06, 1212, surgery and chemo paxitaxtel/carboplatin.  In remission. Recurrence treated with tamoxifen, carboplatin alone, abraxan, then topotacan to no avail. Which chemo next?

Many options: Choosing chemo depends on many factors, so only your doctor can decide what might work for you. Drugs you haven't mentioned include altretamine, capecitabine, cytoxan, (cyclophosphamide) vinorelbine, ifosfamide, etoposide, and irinotecan. There are also several hormonal agents. And a clinical trial might be an option. Check out www.Cancer.Gov for more info. And good luck. ...Read more

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Is Abraxane or Taxol (paclitaxel) better for neuropathy?

Is Abraxane or Taxol (paclitaxel) better for neuropathy?

Not really: Abraxane is a derivative of Taxol. It is employed after recurrent or metastatic pancreas cancers have failed Gemzar (gemcitabine) adding about 8 wks to the overall survival in these patients. The drug,protein-bound paclitaxel is an injectable formulation of paclitaxel, It has almost the same extent of neuropathy. ...Read more

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Is the chemo drug, docetaxel (taxotere) a carboplatin based duplex ?

Is the chemo drug, docetaxel (taxotere) a carboplatin based duplex ?

YES DOUBLET: Taxotere (docetaxel) + carboplatin: is a combination regimen used in certain cancers like lung, ovary and breast (with herceptin). ...Read more

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Why has the drug temozolomide replaced the combination of procarbazine, carmustine and vincristine?

Why has the drug temozolomide replaced the combination of procarbazine, carmustine and vincristine?

Newer treatment: In treatment of Cancer, newer drugs come along and are then compared to the standard(old/conventional treatments). If the new treatment if better(more effective or less toxic) then the new drug takes over and the older drugs put on the back burner. That is what has happened in this instance. This is what has happened in the treatment of brain tumors. ...Read more

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Can gemcitabine be substituted for taxotere (docetaxel)?

Can gemcitabine be substituted for taxotere (docetaxel)?

Gem for taxotere (docetaxel): Short answer is no. It cannot be substituted. Now depending upon the underlying cancer whether lung, breast, pancreatic or any other primary solid tumor, one can use taxol, Abraxane or Navelbine (vinorelbine) (they are taxanes like taxotere). If we want to move to a different agent altogether, then Gemzar or a no of other drugs would be available depending upon what the primary tumor is. ...Read more

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What can prognosis b like for metastic colon cancer that chemotherapy oxyplatin and raltitrexed ?

What can prognosis b like for metastic colon cancer that chemotherapy oxyplatin and raltitrexed ?

Colon mets: Not having your chart and you in front of me makes it very hard to give you an accurate idea on prognosis. When chemo is started, that means your CA cells have gone beyond the boundaries which would have made txing it simple. The simpler the tx, the better the prgns. The harder the tx, the worse the prgns. On a positive note, f/u with your docs, stay faithful, and you might get a pleasant surprise ...Read more

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Is herceptin (trastuzumab) effective in treating bowel cancer?

Is herceptin (trastuzumab) effective in treating bowel cancer?

No: There is no evidence that Herceptin (trastuzumab) is useful in treating colon cancer. It' s use has been expanded to patients with metastatic esophageal and stomach cancers who over express the her2 protein ...Read more

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How effective is avastin (bevacizumab) as targeted therapy for the metastatic colorectal cancer?

How effective is avastin (bevacizumab) as targeted therapy for the metastatic colorectal cancer?

See below: It is not a curall for colon cancer but is effective therapy to a large extent it depends onthe size and wehre it is. Almost certianly it requires more than this drug to get a cure if acure is possible. ...Read more

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Liver and peritoneal mets for mcrc patient . What is approx survival With chemo , oxyplatin and raltitrexed ?

Liver and peritoneal mets for mcrc patient . What is approx survival
With chemo , oxyplatin and raltitrexed ?

We can not guess: We can not tell you what the approx. survival as we do not have all the information to make a comment on the approx. survival You should discuss with your treating Oncologist There are second and third line treatments as well which may change the course ...Read more

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Which is more effective: Avastin (bevacizumab) or Erbitux?

Which is more effective: Avastin (bevacizumab)  or Erbitux?

Identical: Data on Bevacizumab or Erbitux in patients with metastatic colorectal cancer, patients who do not have a KRAS 12/13 gene mutation, have nearly identical survival rates. These identical results were seen after chemotherapy, where survival with chemo alone was about 5 months vs. 7-8 months using either bevacizumab (Avastin) or cetuximab (Erbitux). ...Read more

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For what cancers does chemotherapy with cytoxan, (cyclophosphamide) 5-fu help?

For what cancers does chemotherapy with cytoxan, (cyclophosphamide) 5-fu help?

Not a standard treat: Cytoxan (cyclophosphamide) and 5-fu jused to be used as first line chemo for breast cancer, but there are much more effacious drugs available now. I would not use these drugs now as first line treatment fofr anything except in special circumstances. ...Read more

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What are trastuzumab and herceptin?

What are trastuzumab and herceptin?

Biologic Therapy: Herceptin/trastuzumab is an antibody to a cell surface proteint coded for by the her2neu gene. Its present in some normal cells but in a subset of breast cancers (10-15%) there are multiple copies of the gene producing large amounts of the protein. The herceptin/trastuzumab antibody binds to that protein and reduces that aggressive nature of her2+cancer. It is usually given with chemo. ...Read more

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Diagnoged with cutaneous tcell lymphoma .Treated with eletron beam.Interferon, gemcitabine, anthracycline, etoposide, procarbazine without improv.I'm 64 y?

Diagnoged with cutaneous tcell lymphoma .Treated with eletron beam.Interferon, gemcitabine, anthracycline, etoposide, procarbazine without improv.I'm 64 y?

There are new agents: There are several new agents for this disease. It is uncommon and you need a good assessment of the status of both your disease and your ability to take treatment. There are oral agents, antibodies, drugs like velcade (bortezomib) that might be helpful. I would suggest an evaluation by an oncologist who is familiar with this disease. ...Read more

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Dr. Lynne Weixel
33 doctors shared insights

Paraplatin (Definition)

Paraplatin is an aklylating agent which is a ...Read more