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Doctor insights on: Aldosterone Serum Lc Ms Ms

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?+oligoclonal in csf, + opt neuritis,vep abn,EMG Abn, ocular CT abn,neuro cog test abn. No lesions. ? MS. +s/s- n/t legs,balance,speech.ms imitat.Neg

?+oligoclonal  in csf, + opt neuritis,vep abn,EMG Abn, ocular CT abn,neuro cog test abn. No lesions. ? MS. +s/s- n/t legs,balance,speech.ms imitat.Neg

Clarification: You have multiple issues, and most would strongly implicate MS. But if an MRI of both brain and spinal cord is normal, you do NOT have MS. However, several other possibilities exist, and you need to clarify your diagnosis. May help to obtain another opinion. ...Read more

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Dr. Narina Baburyan
374 doctors shared insights

Aldosterone (Definition)

Aldosterone is a steroid hormone (mineralocorticoid family) produced by the outer section (zona glomerulosa) of the adrenal cortex in the adrenal gland. It is involved in blood pressure regulation, potassium ...Read more


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2.8 oligoclonal bands IgG in CSF. Zero serum bands in CSF. Why does Mayo Clinic standards require 4 oligoclonal IGg CSF for MS diagnosis?

Other causes: Oligoclonal bands can be present in some other conditions such as infections and inflammation of the central nervous system. Increasing the threshold for diagnosing MS by requiring at least 4 oligoclonal bands, allows to exclude these other causes and diagnose MS with greater certainty. ...Read more

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Been diagnosed with peripheral neuropathy blood test showed high immunoglobulin m w/polyclonal gammopathy. Kappa/lambda increase. Possible meaning?

Been diagnosed with peripheral neuropathy   blood test showed high immunoglobulin m w/polyclonal gammopathy. Kappa/lambda increase. Possible meaning?

PlasmaCellDIsorder: May have plasma cell disorder/multiple myeloma. Plasma cells are a type of white blood cells that produces immunoglobulin(antibodies). Multiple myeloma is a cancerous or excessive proliferation of these plasma cells which may lead to excessive high levels of calcium/bone pain/renal failure/anemia (low blood counts). Need to see hematologist (blood doctor specialist). ...Read more

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CSF IgG is 2.6, CSF Albumin is 28, CFS IgG/Albumin Ratio is 9%. Could this indicate MS or Lyme Disease if clinically the symptoms fit?

CSF IgG is 2.6, CSF Albumin is 28, CFS IgG/Albumin Ratio is 9%. Could this indicate MS or Lyme Disease if clinically the symptoms fit?

Test results: The IGG Index requires a comparison to the IGG in blood and CSF. It is a nonspecific test for inflammatory diseases like those you referred to. What were the blood levels? A better test for MS is CSF oligoclonal bands. Do you have that? Along with an MRI result? For Lyme disease you would want a CSF ELISA or Western blot for Lyme proteins. Hope that helps. ...Read more

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LP Done. Monocytes 1%, Serum IgG 587/mg/DL,Albumin 4100ml,IGG Index 1.1mg,WBC 23/mm3,RBC 1/mm3, CSF IGG 3.6 mg/DL,Lymphocytoid 97%, protein, neutrophils, glucose, CSF albumin all norm. Any ideas?

LP Done. Monocytes 1%, Serum IgG 587/mg/DL,Albumin 4100ml,IGG Index 1.1mg,WBC 23/mm3,RBC 1/mm3, CSF IGG 3.6 mg/DL,Lymphocytoid 97%, protein, neutrophils, glucose, CSF albumin all norm. Any ideas?

CSF Results: If I am reading the results correctly, there appears to be a mononuclear pleocytosis with normal protein, glucose and essentially normal immune response. The fluid analysis cn be seen in many disorders including viral meningitis. Need additional information. ...Read more

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Serum free light chain test shows normal kappa (8.7mg/dl), low lambda (3.80), high kap/lam ratio (2.31). Serum $ urine electrophoresis show no monoclonal protein, nor does serum immunofixation. Likely MGUS, myeloma, or admyloidosis? CBC/met panel ok.

Serum free light chain test shows normal kappa (8.7mg/dl), low lambda (3.80), high kap/lam ratio (2.31). Serum $ urine electrophoresis show no monoclonal protein, nor does serum immunofixation. Likely MGUS, myeloma, or admyloidosis? CBC/met panel ok.

False positive rate: There is 30% or so false positive rate of kappa/lambda ratio in people without MGUS, myeloma or other disorders. For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex. ...Read more

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Aldosterone 161 pmol/l - renin/aldosterone ratio 5 - renin 11.4 ng/l - angiotensin II 8ng/l. I have postural orthostatic tachycarda. Why low angioten?

Aldosterone 161 pmol/l - renin/aldosterone ratio 5 - renin 11.4 ng/l - angiotensin II 8ng/l. I have postural orthostatic tachycarda. Why low angioten?

All connected: I am not an expert on this and you don't mention your lab standards so it is hard to say, but they are all connected to each other to regulate the volume of fluid and salt held or released by your kidney and there for your blood pressure. Too little salt then too little volume of blood and BP drops when you stand. ...Read more

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More info on serum immunofixation..no monoclonal proteins detected.a faint IgG labda cannot be ruled out.suggest repeat 6 mths.igg 841 IgA 251 IgM 44.

More info on serum immunofixation..no monoclonal proteins detected.a faint IgG labda cannot be ruled out.suggest repeat 6 mths.igg 841 IgA 251 IgM 44.

Correct advice: It is prudent to retest in about six months to see which way the low level monoclonal spike is going. It may disappear, stay unchanged or increase in amount. The next step will depend on the direction of the quantity of the protein. Your immunoglobulin levels are normal. There is no need to worry. ...Read more

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ACTH challenge done10am, baseline ACTH less than 5, cortisol is at 8 (mayo range) symptoms of Adrenal fatigue, Autoimmune, pots. Tests still needed?

ACTH challenge done10am, baseline ACTH less than 5, cortisol is at 8 (mayo range) symptoms of Adrenal fatigue, Autoimmune, pots. Tests still needed?

What test?: Are you asking whether the ACTH challenge is needed after it has been done? This is best discussed with your endocrinologist who can explain to you the rationale behind his request. ...Read more

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MGUS iggLambda .19 for 1yr. FLC lambda8.04 stable. Kappa drop<1 from 4.2 no ratio calculable.IGM 27 SPEPGammaGlob .63 Doc not avail SLE tooThoughts?

MGUS iggLambda .19 for 1yr. FLC lambda8.04 stable. Kappa drop<1 from 4.2 no ratio calculable.IGM 27 SPEPGammaGlob .63 Doc not avail SLE tooThoughts?

MGUS: There are multiple issues regarding your health. MGUS is actually the simplest. With spike at a concentration of 0.19 and stable, you are at no immediate risk. The risk of myeloma is about 1%/year, but it does require regular follow-up. See this site for info. http://www.mayoclinic.org/diseases-conditions/mgus/basics/definition/CON-20026422 ...Read more

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Recently had pituitary surgery. Current cortisol levels bl 4.1, 30 min a/i 18.6, acth plasma level 6. All numbers seem low, dr said norm. Second opin?

Recently had pituitary surgery. Current cortisol levels bl 4.1, 30 min a/i 18.6, acth plasma level 6. All numbers seem low, dr said norm. Second opin?

Don't know enough: About your case to be specific. I assume the "a/i" is after syncortropin injection, which is an appropriate response, but only checks your adrenal glands. Cortisol and acth are slightly low but not dangerously so. I would discuss your concerns with your doctor. ...Read more

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Ana positive 160 poss mtcd w/o lupus markers. What can cause 300 mg/dL lambda 200 lambda if no paraprotein? Check igd/e? Urine spot lambda bjp found

Ana positive 160 poss mtcd  w/o lupus markers. What can cause 300 mg/dL lambda 200 lambda if no paraprotein? Check igd/e? Urine spot lambda bjp found

BJP: Bence Jones proteins, light chain, occur in multiple myeloma , lymphomas/chronic leukemias, monoclonal gammopathy of undetermined significance which can go on to myeloma at the rate of only 1%/yr -small risk),amylodosis,cryoglobunemia, Autoimmune disease can give false positive. Check IFE & bone marrow http://www.livestrong.com/article/372234-about-multiple-myeloma-and-bence-jones-protein/ ...Read more

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Adnorm. Blood & cfs results: high: CSF protein-47, high cfs albumin-30.9; low total protein-5.7, low gamma globulin-.5, low IgG quantitative -621 worry?

Adnorm. Blood & cfs results: high: CSF protein-47, high cfs albumin-30.9; low total protein-5.7, low gamma globulin-.5, low IgG quantitative -621 worry?

CSF: Some experts consider CSF protein levels to be normal if the value is equal to or below your age in years. I don't think in your case there is a reason to worry. Other CSF components are important as well. Check with your physician to see if there is any reasons to worry. Hope you feel well soon. ...Read more

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Ana 160:1 with u1rnp 5 u/ml. Other lupus screens negative. Pulmonary hypertension, Renal failure reverses with bicarbonate (sodium bicarbonate). Can it be mtcd/sjogren?

Ana 160:1 with u1rnp 5 u/ml. Other lupus screens negative. Pulmonary hypertension, Renal failure reverses with bicarbonate (sodium bicarbonate).  Can it be mtcd/sjogren?

Unlikely: None of these would be typical presentations of either MCTD or Sjogren's syndrome. You need a good internist or rheumatologist on your care team to help winnow the possibilities and care for your extant medical problem. Best wishes. ...Read more

Serum (Definition)

Serum is the component of blood that does not contain cells or clotting factors. It does contain electrolytes an ...Read more