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Doctor insights on: Aldosterone Plasma Renin Act Ratio

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Low aldosterone, normal renin. Sodium 141(135-145), potassium 3.4(3.5-5.0) confused, shouldnt sodium be lower if low aldosterone and potassium higher?

Low aldosterone, normal renin. Sodium 141(135-145), potassium 3.4(3.5-5.0) confused, shouldnt sodium be lower if low aldosterone and potassium higher?

Sodium is difficult: Sodium regulation is complex and not directly related to any single hormone. Mineralocorticoids like Fludrocortisone can increase sodium a bit and do cause sodium retention of sodium, but the sodium level is mostly regulated by a hormone called adh (vasopressin). ...Read more

Dr. Narina Baburyan
372 doctors shared insights

Aldosterone (Definition)

Aldosterone is a steroid hormone (mineralocorticoid family) produced by the outer section (zona glomerulosa) of the adrenal cortex in the adrenal gland. It is involved in blood pressure regulation, potassium ...Read more


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Does testosterone raise circulating aldosterone in the body?

Does testosterone raise circulating aldosterone in the body?

Testosterone aldo: When testosterone is given as a supplement in men with "low T", fluid retention is often noted as a side effect. The cause of this fluid retention is complex, and not just related to aldosterone levels. In a normal male with normal testosterone, this is not really a factor. ...Read more

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Globulin level: 4.5, Albumin level: 3.9, Total Protein: 8.4, Albumin/Globulin Ratio: 0.9, AST: 68, ALT: 105. What do these levels mean?

Globulin level: 4.5, Albumin level: 3.9, Total Protein: 8.4, Albumin/Globulin Ratio: 0.9, AST: 68, ALT: 105. What do these levels mean?

Need med history: You need to tell us why was this test done. Did you have some complaints? Once we know your symtoms, if any, it is easier to interpret your lab results. Your liver enzymes are slightly high and so is the globulin level which can occur due to liver problems like Hepatitis. Your doctor needs to recheck these labs in another one or two months and find the cause?hepatitis? ...Read more

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What is plasma acth cortisol response?

What is plasma acth cortisol response?

Test adrenal fxn.: This test is to check on whether or not your adrenal glands are working right. The acth action is to increase production and release of corticosteroids. In the test, a small amount of synthetic acth is injected and the amount of cortisol the adrenals produce in response is measured. This is used to check for things like primary and secondary adrenal insufficiency, and addison's disease. ...Read more

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What does a high plasma renin act, lc/ms/ms mean?

What does a high plasma renin act, lc/ms/ms mean?

Renin...: ...Is the hormone kidneys make to raise blood pressure. If your blood pressure is low, this is an appropriate response by the kidneys. If it is high, it might represent a problem such as narrowing of the renal artery. ...Read more

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What does "plasma aldosterone concentration" mean?

What does "plasma aldosterone concentration" mean?

Aldo concentration?: The concentration of a analyte is the amount of the substance in a specified volume of blood. So is Aldo concentration is 10 it may mean there are 10 ng/ml. Different labs express if differently as well. So best to ask your team what values your lab uses ...Read more

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What is plasma osmolarity? Plasma osmolality?

What is plasma osmolarity? Plasma osmolality?

Conc. electrolytes.: These refer to the concentration of electrolytes in the body/plasma, or the electrolyte-water balance. These measure the same thing, only that osmolality is the number of osmoles per kilogram of solvent or osm/kg, while osmolarity is the number of osmoles per liter of solution or osm/ltr. Osmolality excludes the solute, while osmolarity includes it, so osmolality has a slightly higher reading. ...Read more

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Aldosterone 161 pmol/l - renin/aldosterone ratio 5 - renin 11.4 ng/l - angiotensin II 8ng/l. I have postural orthostatic tachycarda. Why low angioten?

All connected: I am not an expert on this and you don't mention your lab standards so it is hard to say, but they are all connected to each other to regulate the volume of fluid and salt held or released by your kidney and there for your blood pressure. Too little salt then too little volume of blood and BP drops when you stand. ...Read more

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What is the difference between plasma renin activity (pra) vs plasma renin concentration (prc)?

What is the difference between plasma renin activity (pra) vs plasma renin concentration (prc)?

See below:: Not all proteins are functionally active, especially in the case of enzymes. Discordance between renin concentration (prc) and renin activity (pra) allows detection of adrenal tumors. See this site for more info. http://www.ncbi.nlm.nih.gov/pubmed/15080782. ...Read more

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Bun createnine ratio high 29, bun 12.99 and createnine 0.44. Sodium136, k 4.23 chloride 99 ,bicarbonate (sodium bicarbonate) 25.4, specific gravity 1.015. ?

Bun createnine ratio high 29, bun 12.99 and createnine 0.44. Sodium136, k 4.23 chloride  99 ,bicarbonate (sodium bicarbonate) 25.4, specific gravity 1.015. ?

No problem: The ratio seems high because your creatinine is lower than usual. There is nothing with a low creatinine. Women tend to have lower creatinine due to smaller muscle mass, as compared to men. You lab results are fine. ...Read more

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Does acth causes both aldosterone and cortisol secretion?

Does acth causes both aldosterone and cortisol secretion?

ACTH ALDO Cortisol: I have seen two families in which ACTH is the major driver for aldo production. They have the syndrome called GRA (Glucocorticoid Remedial Aldosteronism) caused by a cross over mutation in the genes controlling aldo production so that the major controller of aldo is ACTH. As you are young and making this question if you also have HTN your team should consider this. Many do not have low K. ...Read more

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Protein Total Serum 8.7 Globulin Serum 4.20 Albumin/ Globulin Ratio 1.07 ALP 132 Urea/ CreatinineRatio 18.54 rest normal . Any worries here ?

 
Protein Total  Serum  8.7
Globulin Serum 4.20
Albumin/ Globulin Ratio 1.07
ALP  132
Urea/ CreatinineRatio 18.54
rest normal . Any worries here ?

Need more info.: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, there is no immediate concern, however, your globulin level may be higher than normal and you should discuss it with the doctor who ordered the tests. For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Drink enough water daily, so that your urine is mostly colorless. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex. ...Read more

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Sodium serum 144, potassium serum 4.7, chloride serum 102, carbon dioxide 23, calcium serum 10.3 RBC 6.36, and hematocrit 52.6% what could this be?

Sodium serum 144, potassium serum 4.7, chloride serum 102, carbon dioxide 23, calcium serum 10.3 RBC 6.36, and hematocrit 52.6% what could this be?

Probably dehydration: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, since all of these values are elevated, you were likely dehydrated when blood was drawn, however, you should discuss the findings with your doctor. ...Read more

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Low aldosterone ~3, normal renin. Low Na, co2, high k in blood. Creatinine 1.4-2.2 in same week.Can type 4 RTA cause this fluctuation in diabetic ckd?

Creat fluctuates: Many things cause Cr to go up or down. So need to answer these questions. 1.What meds r u taking? 2. Any imaging procedure with contrast? 3. recent dehydration? 4 recent illness" and many more. When you had gotten all this together consult with me and can probably help figure out what is going on. ...Read more

Plasma (Definition)

It is the fluid portion of both the blood and lymph system in which the ...Read more