Doctor insights on:
Aldosterone Level 2
Tough to answer in a short space.
Please go online and type in "elevated aldosterone levels".
Start at the top and slowly work your way down.
It might be hard at first but the more you read the more you will understand.
There is also a section "Images" but that is much more difficult to fully understand. ...Read more
Correct measurement: Aldosterone levels vary quite a bit with even position. First make sure that it is measured correctly. Truly high levels of aldosterone may be related to overgrowth or tumor in the adrenal gland, or be secondary to high renin levels driving higher production. Further labs and imaging may be needed to accurately diagnose. Discuss with your doctor. ...Read more
I have been taking spiro for hyperaldosteronism for a year. By now has my aldosterone level returned to normal and will I ever be able to stop taking?
It is unlikely: If you have conn disease you will likely need for long. But have to know if your hyperaldestronism is temporary to suggest duration of treatment. ...Read more
Could be: Could be a sign of congenital adrenal hyperplasia with one of several enzyme defects. This is rare. Depends on who's ordering the test. If endocrinology, this is the reason. Adrenal fatigue is a popular diagnosis now but really represents metabolic stress and is a reaction of the system to stress. The answer is not to address the symptom of the stress but to address the stress itself. ...Read more
If there is a normal level of renin, there should be a normal level of angiotensin II and aldosterone right? So low angiotensin II = low aldosterone?
Aldosterone: Not really. It depends upon sensitivity of adrenal galnds to angitensin ii. ...Read more
Poor correlation: Hi. Oral cortisol (aka hydrocortisone) does not reliably affect ACTH secretion nor aldosterone levels. That is somewhat unfortunate for those of us treated adrenal insufficiency, since determination of proper dose is based solely on clinical response, and not labs. Aldosterone is driven by the renin-angiotensin system bypassing the pituitary. UIHC is excellent, so you have great docs close at hand ...Read more
27y/o f w/very high BP - renin level is 6.4, aldosterone is 47.6. Just stopped birth control pills...What does this indicate, and what could cause it?
HBP in a 27 year old: Your doctor was checking you for conn's (c) syndrome. It is ruled out by your aldosterone/renin ratio of >7 (47.6/6.4). To diagnose c, the ratio has to be > 23. You need to be evaluated for a renal artery stenosis (ras), as you are 27 and are too young have essential hypertension and may have a ras causing it. Get referred to a vascular surgeon for a renal angiogram to see if you have a ras. ...Read more
What should a CAH pregnant woman look out for? Now on hydrocortisone with normal aldosterone level.
Serum androstenedione, testosterone, and 17-hydroxyprogesterone should be measured quite regularly and any increase needed in your hydrocortisone should be taken right away.
Symptoms can be quite tough to pick up on in pregnancy because you will already have many new symptoms and signs which are unique to being pregnant which is why we monitor through regular serum testing. ...Read more
My potassium levels are consistently low so doc wants to order blood tests to check aldosterone & renin blood levels. I'm on propranolol. Is that ok?
Hyperaldosteronism: 21 M Louisiana notes K low & doc wants to test aldo & renin. I'm on propranolol. Is that OK? ANS: better to test off all BP meds atleast 6 wks. I specialize in aldo % happy to do 2nd opinion. 1st need to find cause of low K and a 24 hr urine for Na, K and creat and plasma renin and aldo off meds is best start. See my Yahoo Group at [email protected] Com 2, 000 like u. ...Read more
A cause of high BP: It is not very useful used alone without testing for plasma renin activity. Ask your doctor why he is recommending it. ...Read more
Aldosterone was 2 ng/dL (fasted, early morning, upright) is this normal or low? Does it warrant further testing? Cortisol was high/normal 22.2 mcg/dL
More history: I don't know much about your history or what has caused you to have this testing in the first place so I won't be of much help, BUT the aldosterone level is low and may warrant further testing for Cushing's syndrome, 17-alpha-hydroxylase deficiency, Liddle's syndrome, ectopic ACTH syndrome, or mutations of your mineralcorticoid receptors. You need to talk to your doctor for more direction. ...Read more
Adjust chemistries: Aldosterone is important for adjusting the amount of salt excreted in the kidney. Too much salt excreted can cause low blood pressure and too little salt excreted can cause hypertension. Aldosterone is also important for regulating potassium excretion in the kidney. If blood potassium is allowed to go too high or too low, people can have life-threatening abnormal heart rhythms. ...Read more
Is an a.m. Aldosterone of 6ng/dl on the low side? Range is < or = 28 which seems dumb because a value of 0 or 1 would be "in range".
No: That is an acceptable level in and of itself, but it must be evaluated in the context of other hormonal levels and other symptoms and signs you are experiencing. ...Read more
The concentration of a analyte is the amount of the substance in a specified volume of blood.
So is Aldo concentration is 10 it may mean there are 10 ng/ml.
Different labs express if differently as well. So best to ask your team what values your lab uses ...Read more
Counteracts effects: Aldosterone is a hormone produced by the body which acts to reabsorb sodium from the urine, which is very helpful during periods of dehydration. Diuretics counteract this activity by promotng sodium excretion in the urine. There are many types of diuretics but some like spironolactone directly inhibitthe activity of aldosterone. ...Read more
Aldo of 10: In order to be able to interpret an aldo level in the urine you must know your salt intake measured in that 24 hr urine. If urine Na is low then this is a low urine aldo as low salt in diet increases aldo. If your salt intake is high then this may be a normal urine aldo. You must ask the lab that did the test for their normal range based on salt intake. Has K ever been low? This may lower aldo ...Read more
Physiology: Hi. Aldosterone is primarily there to regulate renal handling of sodium, potassium, and acid. Urine concentration/osmolality is more a function of anti-diuretic hormone (ADH) regulating tubular luminal (phenobarbital) water channels and the ambient solute gradient in the loop of Henle. Water follows sodium in general, but the kidneys place quite a degree of regulation on this, so aldo has trivial effect on conc. ...Read more
Function Aldosterone: 48 F form MI asks what is "function" of aldosterone. Its first function is to keep you from dying of salt depletion. Second it keeps you from dying of high blood potassium. It acts on the kidney to increase salt (Na) retention when your body salt is too low: such as from diarrhea, vomiting, sweating, low alt diet. If you have no aldo you die of salt depletion unless you eat salt by handful. ...Read more
ACTH ALDO Cortisol: I have seen two families in which ACTH is the major driver for aldo production. They have the syndrome called GRA (Glucocorticoid Remedial Aldosteronism) caused by a cross over mutation in the genes controlling aldo production so that the major controller of aldo is ACTH. As you are young and making this question if you also have HTN your team should consider this. Many do not have low K. ...Read more
An article from a credible source says to be tested for aldosterone when having a hypertension resistant situation (like me). Agree with testing?
See below: You shoulg be tested for several things, given your situaton. ...Read more
Saline intake aldo: Well depends on how much saline you are intaking. If you mean infusion IV or a very large salt meal aldo will go down within minutes unless you have a problem like an adrenal adenoma making too much aldo (and HTN). or a renal artery stenosis causing HBP. I can think of no reason it would go up unless the before and after saline infusion bloods were mixed up. ...Read more
Testosterone aldo: When testosterone is given as a supplement in men with "low T", fluid retention is often noted as a side effect. The cause of this fluid retention is complex, and not just related to aldosterone levels. In a normal male with normal testosterone, this is not really a factor. ...Read more
AII vs aldo and salt:
Aldo causes more Na retention and water follows salt.
But depends on circumstances. AII is major drive to aldo production so if AII high get same effect if you don't die form the severe HTN from excess AII.
Both can be counteracted if you eat less salt. I am a specialist in the renin angiotensin aldosterone system and happy to consult with you. ...Read more