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Doctor insights on: Aldesleukin Medication

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Results of trial of proleukin (aldesleukin) in recent onset type 1 diabetes?

Results of trial of proleukin (aldesleukin) in recent onset type 1 diabetes?

Ongoing Study: According to clinicaltrials. Gov, the phase I trial is still on-going; there are no results yet. ...Read more

Dr. Bernard Seif
13 Doctors shared insights

Aldesleukin (Definition)

Aldesleukin is a cancer-related immune system affecting agent which is a ...Read more


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Can phase I trial of proleukin (aldesleukin) and Rapamune lead to type 1 diabetes?

Can phase I trial of proleukin (aldesleukin) and Rapamune lead to type 1 diabetes?

NIH study: The combination of these drugs is being studied in adult patients already diagnosed with type 1 diabetes. The thought is that the combination might help slow down the progress of diabetes. The study isn't complete yet. If there is another phase 1 trial using these drugs in a different study, the investigator should be approached with your question. ...Read more

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Phase I trial of proleukin (aldesleukin) and Rapamune in recent onset type 1 diabetes, what to do?

Phase I trial of proleukin (aldesleukin) and Rapamune in recent onset type 1 diabetes, what to do?

Phase I trials: This is a question best asked of your endocrine specialist. I suppose you are contemplating entering the trial? Do your research and make sure that your questions are answered, be sure that you are willing to make the necessary time commitment. Discuss with family and trusted peers/friends before deciding to join a study.
http://clinicaltrials. Gov/show/NCT00525889 ...Read more

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Any good results from the phase I trial of proleukin (aldesleukin) and Rapamune in recent onset type 1 diabetes?

Any good results from the phase I trial of proleukin (aldesleukin) and Rapamune in recent onset type 1 diabetes?

Probably not: It appears that a phase 1 trial of these medications was attempted in 2007, but results were never published. This probably means that the trial was abandoned. Years ago, another immunosuppressive med was used (cyclosporin) to treat early Type 1 diabetes and was successful in preserving pancreatic function. However further studies were abandoned because of excessive toxicity of this class of med ...Read more

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What makes Trovax different from other kidney cancer meds (like nexavar, proleukin, torisel, (temsirolimus) sutent)?

What makes Trovax different from other kidney cancer meds (like nexavar, proleukin, torisel, (temsirolimus) sutent)?

Other drugs worked: Nexavar, torisel, and sutent all received FDA approval because they improved progression free survival.

The initial Trovax trial was terminated early because there was little or no prospect of demonstrating a statistically significant survival benefit compared to placebo.

http://clincancerres. Aacrjournals. Org/content/16/22/5539.long ...Read more

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Why is interleukin important?

Why is interleukin important?

Interleukins: One of a large group of proteins produced mainly by t cells and in some cases by mononuclear phagocytes or other cells. Interleukins participate in communication among leukocytes and are important in the inflammatory response. Most interleukins direct other cells to divide and differentiate. Each acts on a particular group of cells that have receptors specific to that interleukin. ...Read more

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Is Interleukin IL-6 typically elevated with advanced stage lymphoma???

Is Interleukin IL-6 typically elevated with advanced stage lymphoma???

Lymphoma: If you have advanced stage lymphoma, the IL-6 level will not make or break the diagnosis. IL-6 is an inflammatory cytokine and anything from infection to arthritis can increase levels. ...Read more

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What are EPO and interleukin-11?

What are EPO and interleukin-11?

Important proteins: Epo (erythropoietin) is a key hormone (made by kidneys in adults, liver in babies) in stimulating/signalling the production of red blood cells--it is used to treat anemia in folks wth kidney failure. Interleukin-11 is a cellular protein encoded by the gene il-11 and is important is regulation of a megakaryocyte--the cell which makes platelets. Very complex processes. Have fun learning. Good luck. ...Read more

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What is interleukin 12?

What is interleukin 12?

Signaling molecule: Interleukin-12 (il-12) is known as a cytokine, which are small cell-signaling protein molecules that are secreted by numerous cells and are used extensively in intercellular communication. Il-12 is secreted by certain types of immune cells (such as dendritic cells) to regulate other members of the immune cells (for example, natural killer (nk) cells). ...Read more

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Is interleukin 6 (IL-6) elevated in lymphoma?

Is interleukin 6 (IL-6) elevated in lymphoma?

IL6: IL6 is a blood marker of inflammation. It can be seen elevated in some cases of lymphoma or be elevated in other medical conditions not necessarily lymphoma. ...Read more

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Does interleukin inhibit or turn down the immune response?

Does interleukin inhibit or turn down the immune response?

Interleukins: One of a large group of proteins produced mainly by t cells and in some cases by mononuclear phagocytes or other cells. Interleukins participate in communication among leukocytes and are important in the inflammatory response. Most interleukins direct other cells to divide and differentiate. Each acts on a particular group of cells that have receptors specific to that interleukin. ...Read more

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Is interleukin-1 increased in fever?

Is interleukin-1 increased in fever?

IL 1: Interleukins are cytokines. These are chemical substances released by one cell (often inflammatory), which influence the behavior of other cells. Several interleukins, particularly il 1, are known as pyrogens, in that they may induce fever. Since the interactions among these are quite complex it is possible that the fever was induced by one pyrogen which also caused release of il 1. ...Read more

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What makes interleukin-2 and what makes interferon gamma? Are they both made by t-lymphocytes?

What makes interleukin-2 and what makes interferon gamma? Are they both made by t-lymphocytes?

Yes: Interleukin 2 (aldesleukin) is made by t-cells and is important for the growth of other t-cells. Interferon gamma is made by both t cells and natural killer cells and is part of the innate immune response. ...Read more

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What is a "medication HA"?

What is a "medication HA"?

I think: Medication headache....a type of frequent or daily headache. I'm not positive though. Need to see what the context the phrase was used. ...Read more

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What is best pain medication?

What is best pain medication?

There are none...: Even the strongest opiates only "take the edge off" for people in chronic pain. Meds are only one part of dealing with the pain. A useful tool, but pain is so necessary for survival that we are not "allowed" to monkey with it much. In acute pain, the transition from miserable to less miserable can be great. In chronic pain, it's just part of the plan. ...Read more

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I need refills on my medications?

Not here: For that you will likely need the prime service of healthtap. Easier to call your pop imo ...Read more

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Are expired medications effective?

Sometimes: Sometimes they are. For the most part, expired drugs simply lose potency once past their expiration date. There are, however, some drugs that actually become harmful if taken after they expire. As such, it is best to throw out any medications you have after a year. ...Read more

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Which pain medication works better?

No answer: The best drug is the one that works with the lowest side effect incidence. That will change between patients. ...Read more

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Safest medication to take for pain?

ASPRIN: Actually no one has decided on 'safest'. Asprin has been around since before you were born and unless you take too much (yes, too much of anything isn't good) most people are okay with it. If the pain it too severe for asprin you need to know what causes it. Good diagnosis is called for. See the dr. ...Read more

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How can I dispose unused medications?

How can I dispose unused medications?

Several options: You can take them to your local pharmacy for proper disposal. Some medically oriented charities will also take medication for distribution to the disadvantaged. ...Read more

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Please describe the medication: topical?

Please describe the medication: topical?

Applies to skin: Topical just refers to how a medication is applied. In this case to the skin and is meant to treat local skin problems. Some meds are applied to the skin but are meant to be absorbed into the body in which case we use the term "transdermal" since it is meant to pass through the skin to affect the whole body. ...Read more

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What medications are given fordepression?

What medications are given fordepression?

Why R you depressed?: If your depression is affecting your life and/or those around you and you have trouble dealing with it or not knowing how to etc. It is very reasonable to seek help, either from a therapist, your physician/nurse, or both. Psychotherapy may be adequate for some, others may need both meds (many choices, depending on your symptoms/needs) and therapy. Consult doc. Good luck. ...Read more

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What medication is equivalent to covance d?

What medication is equivalent to covance d?

Yes: Covance d is a combination of losartan and hydrochlorthiazide- a diuretic). There are a number of such combinations for the treatment of hypertension. If this is a question of your co-pay, ask your physician about generic alternatives. ...Read more

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What pain medication can be taken for r.S.D.?

What pain medication can be taken for r.S.D.?

RSD, or: Complex regional pain syndrome can be difficult to treat and each patient needs to be treated differently. Opioid medications are definitely not the first option. Consider medications that affect nerve pain most, like neuromodulators such as gabapentin. Clonidine has been found to help some as well. Stellate ganglion blocks can be diagnostic/therapeutic. Consider topical ketamine creams as well. ...Read more

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What medication need to be taken for acidity?

What medication need to be taken for acidity?

Antacid: An h2 blocker (like Pepcid (famotidine) or its generic) once or twice daily, provides relief for many after about a week. If this fails, a proton pump inhibitor (ppi--like Prilosec or its generic) will often work where h2's have failed. If both fail after at least one week trial of each, see your dr or a GI dr for eval. ...Read more

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Would it be okay if I use hash as medication?

Would it be okay if I use hash as medication?

Condition?: There are some conditions that medical marijuana is helpful for. However there can be significant problems related to cannabis use. Thus, would only consider this when prescribed or directed by a physician who is knowledgable in this area. Take care. ...Read more

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I have rhititis. What medication shoud I take?

I have rhititis. What medication shoud I take?

Antihistamine: You can try an over the counter antihistamine to begin with. Would use one that is non drowsy. ...Read more

Dr. Lawrence Kessler
7 Doctors shared insights

Proleukin (Definition)

Proleukin is a cancer-related immune system affecting agent which is a ...Read more