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Doctor insights on: Aldesleukin

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Dr. Katharine Cox
13 doctors shared insights

Aldesleukin (Overview)

Aldesleukin is a cancer-related immune system affecting agent which is a kind of cancer drug.


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Is revlimid (lenalidomide) effective for acute myelogenous leukemia?

Is revlimid (lenalidomide) effective for acute myelogenous leukemia?

Possibly: If the leukemia develops out of a myelodysplasia and has evidence of a 5q-, then possibly. But, the results are mediocre at best. Not curative by any stretch but could possibly slow the leukemia down for a short time. Hope this helps. ...Read more

Dr. Katharine Cox
13 doctors shared insights

Aldesleukin (Overview)

Aldesleukin is a cancer-related immune system affecting agent which is a kind of cancer drug.


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Results of trial of proleukin (aldesleukin) in recent onset type 1 diabetes?

Results of trial of proleukin (aldesleukin) in recent onset type 1 diabetes?

Ongoing Study: According to clinicaltrials.Gov, the phase i trial is still on-going; there are no results yet. ...Read more

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Results of trial of proleukin (aldesleukin) in recent onset type 1 diabetes?

Ongoing Study: According to clinicaltrials.Gov, the phase i trial is still on-going; there are no results yet. ...Read more

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Peripheral t-cell lymphoma cure: chop induction+ifosfamide/mtx + autologous transplant or romidepsim+brenduximab?

Peripheral t-cell lymphoma cure: chop induction+ifosfamide/mtx + autologous transplant or romidepsim+brenduximab?

Complex problem: Cannot comment with 2 lines of information. Need the entire clinical context. If you seek more detailed information get a formal second opinion. ...Read more

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Is cytoxan (cyclophosphamide) chemotherapy?

Is cytoxan (cyclophosphamide) chemotherapy?

Yes.: Generic name of Cytoxan is cyclophosphamide. It is a drug commonly used to treat a variety of cancers, but may also be used to treat some autoimmune disorders, such as lupus. ...Read more

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Effects of leukemia drugs: mylotarg and cytosine arabinoside?

Effects of leukemia drugs: mylotarg and cytosine arabinoside?

Mylotarg-cytarabine: Open these links: http://www.Drugs.Com/mtm/mylotarg.Html http://www.Drugs.Com/mtm/cytarabine.Html.

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Phase I trial of proleukin (aldesleukin) and Rapamune in recent onset type 1 diabetes, what to do?

Phase I trial of proleukin (aldesleukin) and Rapamune in recent onset type 1 diabetes, what to do?

Phase I trials: This is a question best asked of your endocrine specialist. I suppose you are contemplating entering the trial? Do your research and make sure that your questions are answered, be sure that you are willing to make the necessary time commitment. Discuss with family and trusted peers/friends before deciding to join a study. http://clinicaltrials.gov/show/NCT00525889 ...Read more

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Best waldenstrom macroglobulinemiatreatment?

Best waldenstrom macroglobulinemiatreatment?

Many options: Go see a good hematologist who can guide you best. It is soften treated like a lymphoma. Lenalidomide is one good new drug. Another one is ibrutinib. ...Read more

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Discuss monoclonal antibody production?

Discuss monoclonal antibody production?

Monospecific Ab.: Monoclonal antibodies are those that are produced by the identical immune cells that are descended from the same parent cell. They produce anitibodies that bind to only one epitope or site on an antigen. This means that they are monospecific. This makes them useful in things like research because they can isolate a strain purely and completely. ...Read more

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Can phase I trial of proleukin (aldesleukin) and Rapamune lead to type 1 diabetes?

Can phase I trial of proleukin (aldesleukin) and Rapamune lead to type 1 diabetes?

NIH study: The combination of these drugs is being studied in adult patients already diagnosed with type 1 diabetes. The thought is that the combination might help slow down the progress of diabetes. The study isn't complete yet. If there is another phase 1 trial using these drugs in a different study, the investigator should be approached with your question. ...Read more

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Mult.Myeloma relapsed after treatment with velcade (bortezomib), (bortezomib) melphalan&dexamethasone. Melphalan stopped in dec, velcade (bortezomib) in april. Now takes carfilzomib& dexamethasone fever39.5. No infections.What causes fever?

Mult.Myeloma relapsed  after treatment with velcade (bortezomib), (bortezomib) melphalan&dexamethasone. Melphalan stopped in dec, velcade (bortezomib) in april. Now takes carfilzomib& dexamethasone fever39.5. No infections.What causes fever?

Fever could be side : Effects of the chemotherapeutic agents and steroids considering there's no blood infection. Tylenol (acetaminophen) should help control the fever. Follow up with your oncologist. God bless you! http://www.Livestrong.Com/article/36171-herbs-cancer/. ...Read more

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Best first-line treatment for mantle cell lymphoma now: high doses of ara-c+rituximab and autologous sc transplant, or rituximab+bendamustine?

Best first-line treatment for mantle cell lymphoma now: high doses of ara-c+rituximab and autologous sc transplant, or  rituximab+bendamustine?

There is no: Definitive answer to your question. Studies have compared the strategies you mention. The high dose ara-c arm was closed because it was difficult to mobilize stem cells for transplant after these regimens. Bendamustine-r is a good program, and many centers would consolidate a good response with an autograft. ...Read more

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Whats imatinib mesylate?

Whats imatinib mesylate?

Enzyme inhibitor: This drug, gleevec, (imatinib) is used to treat chronic myeloid leukemia and gastro-intestinal stromal tumors. It acts by inhibiting and enzyme produced by tumor cells. ...Read more

Dr. Liawaty Ho Dr. Ho
8 doctors agreed:
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Zytiga (abiraterone acetate) or xtandi for pre-chemo castration resistant prostate cancer? Thoughts?

Dr. Liawaty Ho Dr. Ho
8 doctors agreed:
Zytiga (abiraterone acetate) or xtandi for pre-chemo castration resistant prostate cancer? Thoughts?

Good options: Both are good options. It will depend on safety profiles and the need of using steroid with zytiga (abiraterone acetate) but not for extandi. Discuss further with your oncologist to select which one is the best for you. ...Read more

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What are interferon alpha-2a and pegylated interferon alfa-2a (pegasys)?

What are interferon alpha-2a and pegylated interferon alfa-2a (pegasys)?

2 versions 1 drug: They are the same drug except that the pegylation makes that drug longer acting, so it can be given less often. ...Read more

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What makes Trovax different from other kidney cancer meds (like nexavar, proleukin, torisel, (temsirolimus) sutent)?

What makes Trovax different from other kidney cancer meds (like nexavar, proleukin, torisel, (temsirolimus) sutent)?

Other drugs worked: Nexavar, torisel, and sutent all received FDA approval because they improved progression free survival. The initial Trovax trial was terminated early because there was little or no prospect of demonstrating a statistically significant survival benefit compared to placebo. http://clincancerres.aacrjournals.org/content/16/22/5539.long ...Read more

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Dr. Liawaty Ho Dr. Ho
5 doctors agreed:
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Can doxil (liposomal doxorubicin) treat multiple myeloma?

Dr. Liawaty Ho Dr. Ho
5 doctors agreed:
Can doxil (liposomal doxorubicin) treat multiple myeloma?

Yes: Yes, Doxil (liposomal doxorubicin) can be used to treat multiple myeloma. Discuss further in detail with your oncologist -whether the chemotherapy would be appropriate for your case. ...Read more

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Can gleevec (imatinib) cure retinoblastoma?

Can gleevec (imatinib) cure retinoblastoma?

No data yet...: Gleevec (imatinib) inhibits a number of tyrosine kinases in cells (c-kit, pdgfralpha, c-abl) . There is very recent data that Gleevec (imatinib) may have activity in retinoblastoma, but these experiments where done on isolated retinoblastoma cells grown in culture. There are no clinical trials showing that Gleevec (imatinib) can treat retinoblastoma. Future clinical trials may be planned to address this question. ...Read more

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Dr. Alan Ali Dr. Ali
1 doctor agreed:
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Whats camptosar (irinotecan) for?

Dr. Alan Ali Dr. Ali
1 doctor agreed:
Whats camptosar (irinotecan) for?

Camptosar (irinotecan): Is hormonal antineoplastic medication given by injection in treatment of metastatic colorectal cancers. ...Read more

Dr. Hirenkumar Italia
7 doctors shared insights

Proleukin (Definition)

Proleukin is a cancer-related immune system affecting agent which is a ...Read more