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Doctor insights on: Albumin Globulin Ratio Calculation

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What is the normal range for urine albumin/globulin ratio?

What is the normal range for urine albumin/globulin ratio?

No such thing: Serum Albumin globulin ratio may be used, but it is better to look at individual levels of each protein rather than ratios. There is no valid reason to look for Albumin globulin ratio in urine. ...Read more

Dr. Raj Singh
267 Doctors shared insights

Albumin (Definition)

Albumins are proteins which dissolve in water and are not covered with chains of sugars. The most common is serum albumin. These molecules transport other molecules which don't dissolve in water very well. But its main function is to regulate the amount of water in the blood. Another type of Albumin is the ...Read more


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Is it ok that my albumin and albumin/globulin ratio was a little high in my blood work?

Is it ok that my albumin and albumin/globulin ratio was a little high in my blood work?

Is the globulin hi?: If the reason is because your globulin is high, needs to be attended to with further analysis. Some collagen diseases (lupus, etc.)., myeloma etc. Can present with asymptomatic hypergammaglobulinemia. ...Read more

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Total protein 7.9 albumin 3.7 globulin 4.2. And albumin/globulin ratio is 0.9. Is this concerning?

Total protein 7.9 albumin 3.7 globulin 4.2. And albumin/globulin ratio is 0.9. Is this concerning?

Generically not prob: Overall this is not a problem. Typically you want your Albumin a little higher so it would be helpful to know if you are dieting or have a good amount of protein in your meals. Ratio should be about 1. ...Read more

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I had blood work done. My albumin level was just a little high. Also my albumin/globulin ratio was just a little high. Is that normal?

Normal: Slightly elevated Albumin level is not considered abnormal. Labs are best interpreted in the context of signs/symptoms. ...Read more

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My physical bloodwork came back with a 2.4 albumin/globulin ratio. My total protein was 6.4. Is this something I should have checked into further?

My physical bloodwork came back with a 2.4 albumin/globulin ratio. My total protein was 6.4. Is this something I should have checked into further?

Ignore it: If your other labs are unremarkable and you feel well, this kind of inquiry is not likely to provide any useful information. Many people do not understand that lab reference ranges are set up so that several percent of healthy people fall outside. Best wishes. ...Read more

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A cmp blood test says albumin/globulin ratio is 2.6 (says normal range is 1-2.1). What is this ratio, and what do results mean? Should I be concerned?

A cmp blood test says albumin/globulin ratio is 2.6 (says normal range is 1-2.1). What is this ratio, and what do results mean? Should I be concerned?

I wouldn't worry: High albumin doesn't occur except in dehydration which also raises globulin, so your total globulin is a bit low overall. Chances are you're one of the folks who makes less in the way of antibodies than other folks, at least right now. This level's no danger to you. These investigations are seldom productive and if you feel well, I'd simply be thankful for good health and keep an eye on it. ...Read more

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Total protein 8.3, serum albumin 4.2, serum globulin 3.8, albumin globulin ratio 1.2. Is this abnormal?

Abnormal labs: It would be helpful that for the labs mentioned above. If you. Can find the normal range or reference range and list it than our answer can be more educated and helpful. The reference range does vary from one lab to another. ...Read more

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Worried about cancer. Should I be? I had my blood drawn. Protein total 6.9. Albumin 4.9. Globulin 2.0. Albumin/globulin ratio 2.5. Is this normal?

Worried about cancer. Should I be? I had my blood drawn. Protein total 6.9. Albumin 4.9. Globulin 2.0. Albumin/globulin ratio 2.5. Is this normal?

You're fine: Reference ranges are set so that several percent of healthy folks fall outside. If you have no localizing symptoms, your physical exam (including testicular check) is nonrevealing and your complete blood count is normal without bizarre cells, you're almost certainly not sick with cancer. ...Read more

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Protein Total Serum 8.7 Globulin Serum 4.20 Albumin/ Globulin Ratio 1.07 ALP 132 Urea/ CreatinineRatio 18.54 rest normal. Any worries here?

Need more info.: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, there is no immediate concern, however, your globulin level may be higher than normal and you should discuss it with the doctor who ordered the tests.
For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Drink enough water daily, so that your urine is mostly colorless. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form.
Practice safe sex. ...Read more

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Doc says constant albumin/globulin ratio of 2.2 (4.9/2.2) not rare in some health conditions, so should monitor it. What conditions? Protein is norm.

Doc says constant albumin/globulin ratio of 2.2 (4.9/2.2) not rare in some health conditions, so should monitor it. What conditions? Protein is norm.

A/G Ratio: Normally there is a little more Albumin than globulins, giving a normal a/g ratio of slightly over 1. Because disease states affect the relative amounts of Albumin and globulin, the a/g ratio may provide a clue as to the cause. A high a/g ratio suggests underproduction of immunoglobulins as may be seen in some genetic deficiencies. More specific tests are needed for an accurate diagnosis. ...Read more

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Globulin level: 4.5, Albumin level: 3.9, Total Protein: 8.4, Albumin/Globulin Ratio: 0.9, AST: 68, ALT: 105. What do these levels mean?

Need med history: You need to tell us why was this test done. Did you have some complaints? Once we know your symtoms, if any, it is easier to interpret your lab results. Your liver enzymes are slightly high and so is the globulin level which can occur due to liver problems like Hepatitis. Your doctor needs to recheck these labs in another one or two months and find the cause? Hepatitis? ...Read more

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Blood work results, chloride was low at 98 mmol, anion gap was high at 17.4, glucose was high at 108 mg/dl, A1c was 6.2, albumin/globulin ratio 2.0?

Blood work results, chloride was low at 98 mmol, anion gap was high at 17.4, glucose was high at 108 mg/dl, A1c was 6.2, albumin/globulin ratio 2.0?

Prediabetes: Hi. That A1c is above normal, & if that glucose is FASTING, it is too (it's not abnormal if it's not fasting). They demonstrate "prediabetes", the abnormal state between normal & diabetes. What was your bicarb/total CO2? Unless it was low, anion gap (a calculated value) doesn't mean anything; it's useful in states of ketoacidosis, lactic acidosis, etc). A:G ratio is fine too. Eat healthy, exercise ...Read more

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I want a hematologist opinion pls tel me why n how is there a m spike when protein albumin globulin ag ratio all are in good range?

See explanation: An M spike describes a monoclone (single type) of immunoglobulin. (Ig) If the rest of the normal globulins are low, but there is an excess of one type of Ig, then the ratio of albumin to (total) globuline can still be normal despite presence of an M spike. ...Read more

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Low globulin, high albumin/globulin, high ALT what does it mean?

Need more info: Lab test results need to be interpreted in the clinical context and is best done by the doctor who ordered the test as s/he likely knows your health history. A doctor needs to know the actual values of the results and more clinical information. ...Read more

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Can you tell me how to get my liver to produce the globulin to raise the albumin/globulin level?

Stop worrying: There is no need to treat a lab test result. Actually, a low A/G ratio reflect lowish albumin, which your liver makes for you, and the most abundant globulins are made by your plasma cells instead. If your albumin is not way-low, don't give it another thought. Reference ranges are set so that several percent of healthies fall outside on either end. ...Read more

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My albumin, globulin values came slightly off in blood test. Albumin: 5.1 gm/dl (normal 3.5-4.8) globulin: 2.1 gm/dl (normal 2.5-3.2) shd I worry?

My albumin, globulin values came slightly off in blood test. Albumin: 5.1 gm/dl (normal 3.5-4.8) globulin: 2.1 gm/dl (normal 2.5-3.2) shd I worry?

How do you feel?: First thing to consider is dehydration. Next time you take the test, make sure you are well hydrated, even though you were asked to come fasting; that does not exclude drinking water. If you do not have symptoms, there is no need to worry. ...Read more

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Urea nitrogen24mg/dl. Cholride110mmol/l. Globulin1.8g/dl (calc)albumin/globulin ratio2.5 (calc).Platelet count216thousand/ul. What does this mean?

Urea nitrogen24mg/dl. Cholride110mmol/l. Globulin1.8g/dl (calc)albumin/globulin ratio2.5 (calc).Platelet count216thousand/ul. What does this mean?

Normal labs likely: Lab numbers without a patient are just that, lab numbers. They mean nothing to a doctor without knowing more about a patient. This is more true when labs numbers fall slightly out of range. Certain labs such as potassium (k) have a very narrow range. For instance, a slightly elevated k level may be nothing (erroneous) or could mean a medical emergency in a patient with end stage renal disease. ...Read more

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Last month ast, ALT all normal, albumin, globulin, bilirubin not normal, this month albumin, bilirubin, globulin normal but AST and ALT very high. Possible?

Last month ast, ALT all normal, albumin, globulin, bilirubin not normal, this month albumin, bilirubin, globulin normal but AST and ALT very high. Possible?

Yes: This is not only possible but commonplace. I believe we've met. Cirrhosis is a chaotic system and labs fluctuate based on activity (damage / healing). We're not going to know for certain, but if we could talk to your liver, i'd bet he would tell you he's regenerated a huge number of cells which is why he's working better and has more total cells though still bearing injury. Be glad. ...Read more

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I am on methotrexate. Labs say that albumin/globulin and anion gap are low with bilirubin in urine. Should I be worried?

I am on methotrexate. Labs say that albumin/globulin and anion gap are low with bilirubin in urine. Should I be worried?

Yes: Your physician knows how to handle this. Managing patients on Methotrexate is a matter of weighing the benefits in treating the illness against the predictable danger to the liver. The bilirubinuria is more specific for a liver problem. Trust your physician on this; I trust you stay physically fit and do not use alcohol. ...Read more

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Raised Liver ALT&GGT, no history of being raised before - don't drink. Only new med is thyroxine. Bilrub, ALP, protein, albumin, globulin normal. Why raised?

How raised?: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, it would have been helpful to have the actual values. As a rule of thumb, it the values are more three times the normal limit, it is not an emergency and you may see your doctor at your convenience. ...Read more

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What causes high globulin, but low globulin albumin ratio?

Liver blood tests: The liver is an amazing organ- it does many things including making proteins your body needs. Albumin is a major protein product of the liver. Chronic illness can cause that to decline- esp. If you're not eating. Globulins are other proteins usually made to fight diseases like infections- perhaps you've been fighting an illness for a few weeks/months that explain this pattern. ...Read more

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I had a physical done - and I got my results pt is 8.3 [h] albumin 4.0 [normal] globulin 4.3 [ht] and ratio is 0.9 should I be concerned?

I had a physical done - and I got my results pt is 8.3 [h] albumin 4.0 [normal] globulin 4.3 [ht] and ratio is 0.9 should I be concerned?

Lab data: These values cannot be interpreted in any meaningful fashion without a full assessment of your clinical condition. The best means of assessing this is to discuss the results with the doctor who ordered the tests and it would specifically help to know why they were ordered. Good luck and best wishes. ...Read more

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Dr. Said my blood work was fine but globulin was high at4.4 (norm 2.0-4.0)A/G ratio was low at. 9 (norm 1.0-2.4)Total protein and albumin normal. This ok?

Repeat the test.: Your albumin/globulin ratio will be low with a normal albumin and high globulin, since it is simple a ratio of tests. Higher globulin may mean a chronic inflammatory or infectious disease or condition, leukemia or other bone marrow disease, an autoimmune disease such as lupus or rheumatoid arthritis, liver or kidney disease. In your case, the globulin may be elevated due to a past cold or virus. ...Read more

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I want a hematologist opinion please why Wud there be a m spike when proteins albumin globulins ag ratio are in good ranges pls kindly let me knw? Plsl

SPEP: A monoclonal (M) protein "spike" can occur with a normal albumin and normal immunoglobulin (Ig, eg IgA, IgG, IgM) levels. A monoclonal gammopathy of undetermined significance (MGUS) can be further evaluated for smoldering multiple myeloma (SMM) or symptomatic MM with additional tests. MM patients may have CRAB findings - hyperCalcemia, Renal (kidney) insufficiency, Anemia, and Bone problems. ...Read more