Doctor insights on:
Aggressive Non Hodgkins T Cell Lymphoma Prognosis
Not really: Non-hodgkin's lymphomas are a very large group of diseases. Lymph cell can be called t cells or b cells based on surface proteins. T cell lymphomas are just one group of non-hodgkins lymphomas. There are also several types of those tcell lymphomas. ...Read more
NK/T cell NHL: The treatment is largely determined by the extent of disease. Patients with localized stage, therapy would be combined radiation and chemotherapy. Patients with disseminated lymphoma, combination chemo would be recommended. For most patients who achieve a partial response after induction therapy, a bone marrow transplant as consolidation would be recommended. Discuss with your oncologist. ...Read more
Not exactly...: Cutaneous t cell lymphoma (ctcl) is a disorder of a type of immune cell, the t cell. Hodgkin's disease is a cancer of b cells, another type of immune cell. Thus ctcl is technically a non-hodgkin's lymphoma. However, people typically use 'non-hodgkin's lymphoma' to describe other types of b cell cancers that do not fit the characteristics of hodgkin's disease. Talk with your doctor for more info. ...Read more
Start with this link: Http://www. Cancerresearchuk. Org/cancer-help/about-cancer/cancer-questions/childhood-non-hodgkins-lymphomaGet a more detailed answer ›
What is the prognosis of stage 4 cancer non hodgkins lymphoma b cell with walderstoms IgM protein 4000?
Fairly good: We have good treatments for nonhodgkins lymphoma such that a fairly large proportion of patients are cured and can live a normal life. At least we can keep them alive for many years with the use of chemotherapy along with a biologic agent/immunotherapy drug called rituximab. ...Read more
Multiple fashions: It varies by stage (spread). It can be treated via chemotherapy or radiation therapy. Some use total skin radiation in some cases. In my practice, even when widespread and felt to be "incurable" focal radiation a small number of worst problemsites (say 2 or 3) can make it a long term issue when other methods of treatment fail. It is best to find a team of local md's who treat it often. ...Read more
Yes.: Stem cell transplantation, usually from the patient's own bone marrow (autologous stem cell transplantation) can dure certain types of lymphoma that was not cured by chemotherapy. Transplantation using another person's cells (allogeneic transplant) is more experimental, but also capable of curing patients where other treatments have failed. ...Read more
Depends: Some patients have had great success with such treatment. Depends on the specific cell type. ...Read more
It can be cured: We have good treatments for patients with this diagnosis. It is curable in a majority of patients. So tell us more about it such as... who has it and what is being done to treat it??? ...Read more
Good odds: Stem cells are used following high dose chemotherapy. The cure is effectively achieved with high dose chemotherapy, the stem cells are used to repopulate the bone marrow so that normal blood formation can be revived. This process is commonly used for treatment of non hodgkins lymphomas as a rescue therapy and can salvage/cure about 50% of cases who have filed to get well with initial chemotherapy. ...Read more
Type of NHL: Cutaneous t cell lymphoma (ctcl) is a type of non-hodgkin's lymphoma (nhl), which is a type of cancer of the immune system. Unlike most nhl (which are generally b-cell related), ctcl is caused by a mutation of t cells. The malignant t cells in the body initially migrate to the skin, causing various lesions to appear- reference wikipedia and cancer. Gov. Best wishes. ...Read more
The prognosis for t-cell non-hodgkin's lymphoma (nhl) vs. B-cell nhl depends on multiple factors, but in general t-cell nhl has a worse prognosis.
One reason is that b-cell, cd20+ nhl can be treated with the anti-cd20 monoclonal antibody Rituximab in addition to chemotherapy. We currently don't have such an effective, low toxicity antibody (biologic treatment) for t-cell nhl. ...Read more
There are no obvious: Causitive agents like there is for lung cancer. It doesn't tend to run in families most of the time either. Risk factors for developing it are increasing age, male sex (slightly more common) and being white. It is uncommon in young females such as yourself, but not unheard of. ...Read more
Skin biopsy for some reason tested cd3 but was neg does that ensure no t cell lymphoma or it could still be developing?
Yiour doctor/oncolog: Only your treating doctor can help explain what is going on. Please ask him/her to explain and get your answers from the person putting you thru the biopsies etc. It does not sound anything meaningful to me. ...Read more
My dad has stage 3b non hodgkins lymphoma of the diffuse large b cell type. What are the chances of his survival? First chemo went well.
Can 2 biopsies done at same time rule out cutaneous t-cell lymphoma completely? If symptoms point to ctcl but biopsy was neg when should we re-biopsy?
Not Completely: The average number of biopsies to completely diagnose CTCL is about 6. That said, if the type of CTCL is the common type, mycosis fungoides (MF), and not mimics of MF, then 1 or 2 biopsies could be diagnostic especially if typical patches, plaques of CTCL. If the latter, ancillary tests including molecular clonality T cell test are crucial for diagnosis excluding mimics. Rebiopsy in about 3 mos. ...Read more
A Rare Lymphoma: Hstcl is a rare cancer of the the white blood cells. It usually affects young men with a history of immunosuppression for other diseases like inflammatory bowel disease (uc and/or crohn's) or after an organ transplant. The bad cells usually grow in the liver, spleen and bone marrow. It is treated with chemotherapy and possibly a bone marrow transplant. It unfortunately can be difficult to cure. ...Read more
Itchy skin: Pruritus /itchy skin would be the most common symptoms. Skin manifestation can vary from redness, dryness, lumps, etc. ...Read more
What is the relationship of hepatosplenic t-cell lymphoma and low lymphocyte levels in the blood?
Retained in spleen: The spleen can be quite large and contain really high numbers of malignant lymphocytes. In these cases, both normal and malignant lymphocytes can be low in the peripheral blood. ...Read more
My dad has large diffuse b cell type non hodgkins lymphoma stage 3b.Will he be fine? Its very hard to believe he has cancer. Am I going to lose him?
Maybe: I'm sorry about your dad. If you have doubts, have a couple of pathologists review the biopsy. Very often this is asympatomatic. Maybe 70% overall get a cure. I am glad he has you during this difficult time. ...Read more
My cousin has large cell non hodgkins lymphoma. She has an infiltration of her liver. How is this treated & side effects? She's in stage 3.
Peripheral t-cell lymphoma cure: chop induction+ifosfamide/mtx + autologous transplant or romidepsim+brenduximab?
Complex problem: Cannot comment with 2 lines of information. Need the entire clinical context. If you seek more detailed information get a formal second opinion. ...Read more
Have itchy skin. 2 biopsies with lymphocyte infiltrate no T cell lymphoma. Ana was 640. Could it be autoamune. Have Hypothyroid.?
It could be: If your hypothyroidism is related to an autoimmune disorder, then your skin problem may be as well - guilty by association. Make sure that you have not become allergic to one of the medications you have been taking. There are several options on treatment and I suggest that you consult a dermatologist, a 2nd opinion if needed. ...Read more
Upper arms feel warm to touch, no allergies, past 4 days. What can cause this? Also have been diagnosed with cutaneous T cell lymphoma.
Uncertain but need e: You need to see your oncologist to be certain there is no relationship. As you are immunodeficient -we are concerned about infection. ...Read more