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Doctor insights on: Afp Amniotic Fluid

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What's alpha-fetoprotein (afp) in amniotic fluid?

What's alpha-fetoprotein (afp) in amniotic fluid?

See below: AFP is a protein produced by the yolk sac and liver of a fetus. Since it is in the plasma of the fetus, it can be found in the blood of the mother. ...Read more

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I had an amniotic fluid test which showed a high concentration of alpha-fetoprotein. What does this mean?

I  had an amniotic fluid test which showed a high concentration of alpha-fetoprotein. What does this mean?

AFP in amniotic fl: If an amniocentesis is performed and AFP is detectedin the amniotic fluid, this means that the fetus has an open neural tube defect or an abdominal wall defect. Sonographic evaluation needs to confirm the abnormality. ...Read more

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What is the purpose of amniotic fluid?

What is the purpose of amniotic fluid?

Lung Development: Amniotic fluid initially is filtered from the mother's blood and passes through the pregnancy's membranes to create a nourishing cushion during the first few weeks of development. Later, it is a byproduct (urine) of the baby's circulation which is taken into the lungs during the baby's practice breaths. The fluid pressure then induces growth and opening of the lung's branches. ...Read more

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What causes low amniotic fluid levels?

What causes low amniotic fluid levels?

Circulation issues: The amniotic fluid 'circulates' inside the uterus after it is manufactured including the baby swallowing some of it. If there are genetic problems with the fetus or problems in 'manufacturing' both can cause low levels. ...Read more

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What is amniotic fluid embolism?

What is amniotic fluid embolism?

Maternal illness: As a complication of pregnancy and delivery, amniotic fluid may gain entry into the maternal circulation. It induces intravascular thrombus formation followed by bleeding disorder, and respiratory problems and shock in the mother. ...Read more

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What causes amniotic fluid embolism?

Vein: It is when amniotic fluid enters the bloodstream through the venous system. It can be very dangerous, potentially causing a embolus in the lung. ...Read more

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What are the tests for amniotic fluid embolism?

What are the tests for amniotic fluid embolism?

Clinical and DIC: Amniotic fluid embolism, depending on the amount of fluid getting into maternal circulation can be catastrophic. The diagnosis depends on clinical suspicion and testing for disseminated intra-vascular coagulation, namely low platelet count, elevated pt ptt, abnormal shape of red cells, low fibrinogen and fibrin split products, chest x-ray etc. ...Read more

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Low amniotic fluid at 39 weeks. Should they deliver?

Low amniotic fluid at 39 weeks. Should they deliver?

Probably: If your afi is < 5, yes. If it's borderline, between 5-8, it should be strongly considered unless your cervix is unfavorable (difficult to induce d/t being closed, thick, and/or firm). If they wait, you also need a normal non-stress test (nst) or biophysical profile (bpp). If your afi > 8, it's ok to wait. Discuss this with your OB & make sure you understand "kick counts" & when to go to l&d. ...Read more

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