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Doctor insights on: Advanced Prostate Cancer With Bone Metastases

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Dr. Barry Rosen
4,421 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


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Treatments for prostate cancer with bone metastasis?

Treatments for prostate cancer with bone metastasis?

Many: The first line of treatment for this is androgen deprivation. In addition, there are medicines which reduce the risk of fractures with Denosumab showing the most efficacy compared to zoledronic acid, however with some risk of significant side effects. For more extensive disease, a newer IV radium therapy has shown improved survival. Localized radiation can be effective for painful foci. ...Read more

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Prognosis for hormone refractory metastatic prostate cancer with pathological fracture?

Prognosis for hormone refractory metastatic prostate cancer with pathological fracture?

Prostate cancer: This is an advanced stage of prostate cancer; the good news is there are many new drugs and treatments for men in this stage that have been shown to extend life; in this stage survival is extremely variable from months to years isn't impossible. ...Read more

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What are advanced testicular cancer and another advance cancer such as advanced lung cancer?

What are advanced testicular cancer and another advance cancer such as advanced lung cancer?

Variable: Obviously different cells and location of origin. Other adjectives are differentiation - wild growth histology. Once advanced stage includes spread-metastasis and locations. Testicular can go through local and systemic spread. Similarly lung can grow and invade locally and spread broadly. ...Read more

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I'm concerned about prostate cancer metastasis. Where can prostate cancer spread?

I'm concerned about prostate cancer metastasis. Where can prostate cancer spread?

In theory, prostate cancer cells can spread anywhere in the body: In practice, though, most cases of prostate cancer metastasis occur in the lymph nodes and the bones. Prostate cancer metastasis occurs when cells break away from the tumor in the prostate. The cancer cells can travel through the lymphatic system or the bloodstream to other areas of the body. More commonly prostate cancer metastasis can occur in the: Bones, Lymph nodes, Lungs, Liver, Brain. Rare locations of prostate cancer metastasis include: Adrenal glands, Breasts, Eyes, Kidneys, Muscles, Pancreas, Salivary glands, Spleen. If you've been diagnosed with prostate cancer and you're concerned about prostate cancer metastasis, talk with your doctor about your risk of prostate cancer metastasis and your treatment options. ...Read more

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Stage 4 prostate cancer bone pain?

Stage 4 prostate cancer bone pain?

Bone pain: When prostate cancer spreads it tends to go to the bone where it can cause pain. Tell your urologist or oncologist about the pain and they can order an x-ray. It can be treated so please don't think it is hopeless. ...Read more

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Do people with stage IV metastatic breast cancer often undergo chemo?

Do people with stage IV metastatic breast cancer often undergo chemo?

Yes.: Under certain circumstances hormone therapy might be the initial treatment, but most stage 4 patients eventually undergo chemotherapy treatment. This will depend on age, tolerence for treatment, hormone responsiveness and other tumor characteristics. ...Read more

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Dr. Liawaty Ho Dr. Ho
5 doctors agreed:
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Symptoms of prostate cancer metastasis?

Dr. Liawaty Ho Dr. Ho
5 doctors agreed:

Prostate cancer: The most common metastatic site would be bones-although it also can go to other sites- lymph glands, lung, liver etc.. Symptoms will depend on the location of metastases. Bone pain, fractures would be the symptoms of bony mets. If spread to the adjacent area such as bladder area- blood in urine, lower abdomen pain, prob wi/ urination, obstruction can happen. Weight loss, weakness are common too. ...Read more

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Metastatic breast cancer usually spread to liver?

Metastatic breast cancer usually spread to liver?

It may: Breast cancer can metastascise to many organs. Regionally to the lymph nodes and distantly to other organs. More commonly to the bones, lung, liver, brain and other visceral structures in the abdomen or pelvis. ...Read more

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Is advanced stage colon cancer treatable?

Is advanced stage colon cancer treatable?

Yes and no: It is treatable but not curable. That is, you can treat it and may knock it down for a while ..t but it will always come back. But there are many factors that play into it. See cancer.org or cancer.gov for excellent information on the stage and what to expect. ...Read more

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What are psa and tumor markers for prostate bone metastasis?

What are psa and tumor markers for prostate bone metastasis?

PSA means: Prostate specific antigen. Men all have a level of psa if they have a prostate. Arbitrary normal levels are age & race dependent. If you have prostate cancer, and bones are involved, your psa will likely be greater than 10 ng/ml. Psa levels that double in short intervals are more likely to do this. However, very undifferentiated prostate cancers may not generate psa, and one can have bony mets. ...Read more

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Bone cancer prognosis and remission rate?

Bone cancer prognosis and remission rate?

It depends: There are several cancers that are called bone cancer. To give you an accurate answer i would need to know the type of cancer. Did it start in the bone or is it a cancer that spread to bone? ...Read more

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Hepatocellular carcinoma.All spleen and partial liver resection.Later,secondary systemic cancer metastasis.any targeted therapy or immunotherapy?

Hepatocellular carcinoma.All spleen and partial liver resection.Later,secondary systemic cancer metastasis.any targeted therapy or immunotherapy?

Yes, for both: Hepatocellular Carcinoma is commonly treated with Sorafenib which is a type of targeted therapy. This is a good choice of treatment in case you have not yet received this drug. Immunotherapy using PD-1 inhibitors has also shown some modest evidence of benefit although it is not yet FDA approved for this indication. Ask your oncologist to guide your treatment further. ...Read more

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Metastatic breast cancer has gone to hip bone; prognosis?

Metastatic breast cancer has gone to hip bone; prognosis?

This depends: The answer depends on many factors. How old is the persone, what other medical problems do they have, when did the breast cancer first occur, what other sites are involved, what are the characteristics of the cancer (estrogen, Progesterone receptors, her2/neu status) and what prior treatments were administered are some of the issues that factor into an answer. ...Read more

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Is brachytherapy helpful for a prostate cancer patient who has metastasized cancer cells?

Is brachytherapy helpful for a prostate cancer patient who has metastasized cancer cells?

No.: Brachytherapy is used in the treatment of localized prostate cancer, or cancer that has not spread outside of the prostate gland. If a patient has metastatic disease, treatments need to be systemic, with the aim of halting the growth & spread of the cancer throughout the body. These treatments include hormonal therapy, chemotherapy, and immunotherapy. Urologists & medical oncologists can help. ...Read more

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Should stage 1 breast cancer patients with no lymph node involvement generally receive chemo?

Should stage 1 breast cancer patients with no lymph node involvement generally receive chemo?

Sometimes: While the prognosis for stage 1 breast cancer is excellent, many women may benefit from traditional chemotherapy. This is dependent on the age of the patient, whether the tumor is hormone-sensitive, if the her2/neu receptor is overexpressed, and, in select cases, what the oncotype-dx score is. While "negative" lymph nodes are very encouraging, some breast cancers may travel via the bloodstream. ...Read more

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Can bladder cancer metastasize?

Can bladder cancer metastasize?

Yes: Untreated bladder cancer can metastasize to other organs and structures when left untreated. The more aggressive the bladder cancer, the higher the likelihood of metastasis. It is not unusual for bladder cancer to metastasize. ...Read more

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Gallbladder cancer with severe lung metastasis 4th stage, does chemotherapy work?

Gallbladder cancer with severe lung metastasis 4th stage, does chemotherapy work?

GB cancer is: Uncommon, so few studies done prospectively. Looking at results in people treated empirically, perhaps one person in 10 will respond. That needs to be balanced against side effects that tend to occur in most. Frank discussion about symptom rrelief focus rather than "shrink tumor" at all cost. ...Read more

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How can metastatic breast cancer progress?

How can metastatic breast cancer progress?

It can and it does: Progress of cancer means the cancer is getting worse. This is not uncommon as the cancers tend to spead further in the body and tumors get larger in size especially when the treatment is not working. Cancer is either regressing(with good treatment) or progressing(without treatment or with the ineffective treatment). ...Read more

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Dr. Lynne Weixel
7 doctors shared insights

Prostate (Definition)

The prostate is a gland that lies at the base of the bladder and surrounding a segment of urethra. It secretes a milky fluid that is discharged by excretory ducts into the urethra during the emission of semen. It is clinically important because enlargement of the prostate with age, and prostate cancer are two common ...Read more


Dr. Arnold Malerman
25 doctors shared insights

Bone (Definition)

Bone is a living growing tissue made mostly of collagen (protein that provides soft framework) & the mineral calcium phosphate that adds strength & hardens the framework. Two types of bone are found in the body; cortical (dense compact outer layer) & trabecular (makes up inner layer, ...Read more