Doctor insights on:
Adrucil Topical Cancer Agent
What to do if I use fluorouracil cream(cancer drug) to treat a rash..will I get cancer because of that?
No: Efudex (fluorouracil) cream is a cutaneous method of applying 5 FU ( a chemotherapeutic agent) to cutaneous basal cell and some cutaneous squamous cell Ca's ..It is applied daily x 10 followed by an application of A&D ointment to the same area that has become inflamed. In many cases the skin tumor will completely regress. Sometimes a repeat treatment needed. Should not be used for rashes. Does not cause Ca. ...Read more
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
In combination: Chemotherapy has some benefit in colon cancer when used in combination with other drugs. FOLFOX is an example that when given in the adjuvant setting can be helpful in minimizing local recurrence. In the therapeutic setting immunotherapy is needed possibly in combination with chemo to prolong survival. ...Read more
Very very unlikely: Fluorouracil is a type of chemotherapy, and it works by interfering with dna reproduction. So yes, there is a very tiny chance that it could cause a mutation that would lead to cancer. However, the cream is used on the skin, and very little should be absorbed. The chance that you would get a cancer from it is miniscule. We give the same drug intravenously and by mouth at much higher doses! ...Read more
Very: The majority of small and even intermediate basal cell cancers can be cured by applying EFUDEX (fluorouracil). The resulting erythema is secondary to destruction of local suppressor cells in the tumor field and influx of effector cells to destroy the tumor. The EFUDEX (fluorouracil) is applied locally for 10 days followed by 10 days of A&D ointment May repeat if needed. ...Read more
Just diagnosed with precancerous squamish cell cancer. On efudex (fluorouracil) . What else should I do? I am male, balding, 64, live in ottawa, canada.
Easy to handle: Squamous precancers are called actinic keratoses and often (but not always) result from sun exposure. Efudex (fluorouracil) is hugely effective in changing their environment so they usually just go away without danger to you. They'll kill only if badly neglected. Here in the states, balding guys like to wear ball caps. Have somebody keep an eye on your head and other sun-exposed places as you'll likely get more. ...Read more
What is your opinion on fluorouracil 5 and other treatments you can recommend for skin cancer on nose?
Multiple options: Non-melanoma skin cancer is usually treated by surgery. Choice of other options, 5fu, (fluorouracil) radiation, etc. Usually is based on potential cosmetic result and feasibility of surgery. A very large lesion or one that recurs might not be able to be treated surgically. A lesion on the nose might be a problem re cosmetic result and then the other options are reasonable alternatives. ...Read moreSee 1 more doctor answer
Many: There are a few drugs that use this idea such as abraxane. There are mulle possibilities. Currently an chemotherapy is attached to a carrier molecule and attached to an antibody for breast cancer. Delivery might be less important than targeting weakness in cancer cells more specifically. ...Read more
Medical ethics: With out clinical trails best drugs can not be assessed for effectiveness, it is not with out risk as risks to the human body are known yet, also will loose critical time, . On moral and ethical ground one can't give advise, it is up to you and you decide. Good luck. ...Read more
While it one of: The oldest anti-cancers, it has no marrow suppressive effecs. As a vinca alkaloid, it interferes with the mitotic spindle formation necessary for actively dividing cells. It is used in many pediatric tumors as a cornerstone drug. Leukemias and lymphomas. It does not work very well in most adult solid tumors. ...Read moreSee 1 more doctor answer
It is Jakafi (ruxolitinib): It is a new drug which has been approved recently and is useful to treat a blood disorder called Myelofibrosis where the body doe snot produce enough blood. So this drug has offered some relief(we had no other drug to treat this type of Cancer before Jakafi (ruxolitinib). ...Read more
Various: As stated the typical side effects are inflammation of the bladder which usually resolves. Some patients becoem intolerant and cannot receive the treatment. If BCG is absorbed into the bloodstream it can result in massive infection and (rarely) death. Bcg should never be given if there is obvious blood in the urine. Also the pt shouldvoid into the same toilet for 24 hours after BCG and add bleach. ...Read moreSee 1 more doctor answer
Multidisciplinary: Developing a cancer drug is an involved process that need contributions of chemists, biochemists, molecular biologists, doctors, pharmacologists, and more. Nanotechnology has not played a major role, yet. ...Read more
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