Doctor insights on:
What makes Trovax different from other kidney cancer meds (like nexavar, proleukin, torisel, (temsirolimus) sutent)?
Other drugs worked: Nexavar, torisel, and sutent all received FDA approval because they improved progression free survival. The initial Trovax trial was terminated early because there was little or no prospect of demonstrating a statistically significant survival benefit compared to placebo. http://clincancerres.aacrjournals.org/content/16/22/5539.long ...Read moreSee 1 more doctor answer
Experts, might someone recommend nexavar (sorafenib) for a stage 4 inactive neuroendocrine pancreatic cancer patient?
Possibly: Stage 4 indicates that you have net at a site distant from the pancreas or regional lymph node, likely the liver. Not clear what you mean by"inactive", whether you mean it is stable or not secreting any substance. In any case, sorafenib (nexavar) is being tested in metastatic net in clinical trials (http://clinicaltrials.Gov/ct2/show/nct00131911) & (http://www.Ncbi.Nlm.Nih.Gov/pubmed/23475104). ...Read moreSee 1 more doctor answer
U/s confirmed many nodules.Bx schedules, high platelets, wbc, pot. &anemic.Chronic fever.Low acth 3. Checking addison's, cancer, hashimotos. Any thoughts?
What R symptoms of Glutamate Excitotoxicity.Post OD of Pseudoephdrine I've had severe nervousness,migraines, hyperacusis, hyperinsomnia. Excitoxicity?
See below: Some people develop symptoms of headaches, insomnia, anxiety, mood swings when they ingest too much glutamate in their diet. Pseudoephedrine overdose can cause Headaches, insomnia, anxiety, mood swings, brain hemorrhage and heart attack. Excitotoxicity is the process by which nerve cells are damaged and killed by excessive stimulation by neurotransmitters such as glutamate ...Read more
Ch.Rhinitis 8 yrs, IgE 867, eosinophil count 9, redness&itching during spt.No defect in nose.Is vasomotor rhinitis?Laser desensitization of nose is cure?
Nasal allergies: A high ige and eosinophil count speaks against vasomotor rhinitis. You need to get tested for environmental allergies and determine your triggers and get desensitized to them by allergen immunotherapy. Nasal surgery is not the answer. Seek the opinion of an allergist, not ent. ...Read more
What are the chances of a southern siberian russian having huntington's? I'm adopted from there. Symptoms: tremor, fatigue, dizzy,
I get savage irrational rage & full-body dysesthesia when eating food high in aspartic, glutamic, & arachidonic acid. Why? Nmda receptor dysfunction?
Mch 32.2, auto leuts 53.3, auto lymphs 39.2. history of cancer in family. Gist, lymphoma, pt is feeling confusion and fatigue. Being sent to hemotologist?
Good idea: Considering the high leukocyte count that appears to be mostly the consequence of a significantly increased lymphocyte count, it is a good idea for the patient to consult a hematologist in order to address the possibility of hematologic malignancy, especially chronic lymphocytic leukemia. ...Read moreSee 1 more doctor answer
Translation: I am sorry but this was not translated into English. ...Read more
condropatia rouliana grade 111 1v artropatia patelofemoral
external avanzada in relation probably con hiperpresion
lesion intransustancial 2?
Try again: Not sure of your question. Can you try again? ...Read more
Can bioidentical progesterone, Biest, testosterone, Ativan, Prozac, allergy nasal sprays slow tracer from entering gallbladder during HIDA?
Enlarged pituitary, no adenoma. Neurological endocrine system disregulation incl. fluctuating thyroid hormone w/goiter (when high). High urine pH 9.0.
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Colon cancer 3yrs ago. Surgery, 2spots was in liver..Chemo for 2yrs.Now z tumor is 15 cm& 7.5 wiz spots in lungs!fatigue &dysfunction liver. What help?
NCI: It does not seem as though surgery is an option for you at this time. Body-wide treatment such as chemotherapy is going to be the preferred way to treat this. Seek care at a national cancer institute designated comprehensive cancer center. This will give you the best access to available clinical trials. Another option is to go to the website www.Cancer.Gov and click in the clinical trial link! ...Read moreSee 1 more doctor answer
Possibly: Removal of liver metastases can sometimes be helpful for patients with colon cancer. A remarkable amount of cancer can be removed usually after there has been some response to chemotherapy. If surgery is not recommended alternatives such as radioembolization, chemoembolization, radiosurgery, or rfa or cryoablation may be considered. Get with an experienced team to determine the best course! ...Read moreSee 5 more doctor answers
Post Thyrodectomy (Hurthle cancer) TSH 16.89 (T3 250, T4 0.92). Dr increased Synthroid (thyroxine) 150 to 200 Is it enough? risk of cancer if not more aggressive?
Gradual adjustment: It is prudent to gradually adjust the dose of synthyroid so as to not cause hyperthyroid state. It would be prudent to follow your doctor's advice. ...Read more
35yo m HIV neg. Cd3, cd4, cd8 mildly depressed, cd19 mildly elevated.Fatigue large complaint. Possible causes of immune dysfunction listed?
Horses, not zebras: You don't have "immune dysfunction." you have a mild abnormality of a lab test that shouldn't have been drawn in the first place. Focus on common causes of fatigue, not rare ones. ...Read more
Any dr read this destroying the myth about testosterone replacement and prostate cancer
by abraham morgentaler, md, facs introduction by william fa?
Thyroid from 4cm to 7.1cm. Uptake 20.5%/34%. Fnb significant # multinucleated giant cells with positive pet scan prior to surgery 4 breast ca surgery?
Goiter: A goiter, size increased from 4 cm to 7.1 cm? Suspicious needle biopsy and positive pet scan? Possible breast cancer? You need consult with surgery and endocrinology. More information is needed, but likely you will benefit from thyroid surgery. The pathology exam will make diagnosis, and cancer is a concern. This is complicated, so take a friend with you for your consult. ...Read more
Initial diagnose,Hodgkin stage IIb,bulky.After 4 cycle of ABVD (total of 8 sessions),PET pos. SUV 14.No significa shirinkage in mass.is it refractory?
Possible: Although 4 cycles of ABVD is generally minimum for patients with bulky disease, you should see response by now. If no response at all, you may consider re-biopsy the FDG-avid mass. If biopsy proves refractory disease, consider 2nd line treatment (high dose chemotherapy, stem cell transplant and/or radiation). In addition, re-review of the initial pathology may also be helpful. Good luck! ...Read more