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Adriamycin Cytoxan Taxol And Fertility
Had an ultrasound that showed the liver to be slightly heterogeneous. Can that be due to past chemo therapy with Adriamycin, (doxorubicin) Cytoxan and Taxol?
Hx ILC, tx high dose Adriamycin/Cytoxan 2006. Now, fatigue, difficult swallow, CT scan = one tonsil & lymph nodes in neck enlarged. Risk lymphoma?
Yes: Cytoxan (cyclophosphamide) can be damaging both to eggs and sperm and therefore needs to be monitored closely by your rheumatologist and fertility doctor. Cytoxan (cyclophosphamide) is also considered class d in pregnancy suggesting risk of fetal harm. Long term Prednisone therapy has little effect on sperm production or ovulation. ...Read more
Was on Taxol and didn't work now going on doxil (liposomal doxorubicin) is that......Going to help?
Can you tell me about the long term side effects from the chemotherapy drugs adriamycin (doxorubicin) and cytoxin?
TWO MAJOR ONES: Adriamycin (doxorubicin) and Cytoxan is a great combination regimen used in breast cancer. The major long term side effects for both of these drugs is secondary leukemias, risk is around 1%. For adriamycin (doxorubicin) there is a concern for cardiotoxicity, but risk rises with cumulative dose. Risk is less than 10%. Patients get an echocardiogram or muga scan prior to therapy to evaluate heart status. Talk to your md. ...Read moreSee 1 more doctor answer
Rarely affects it.: Chemotherapy when given over a prescribed period of time such as in the neoadjuvant setting or post surgery rarely effects fertility. In the presence of metastatic disease where long term therapy is given then there is a chance of infertility. This can be true when doxorubicin and Ifex (ifosfamide) are employed for advanced metastatic sarcoma. ...Read more
Taxol (paclitaxel): TAXOL (paclitaxel) is contraindicated in patients who have a history of hypersensitivity reactions to TAXOL (paclitaxel) or other drugs formulated in Cremophor® EL (polyoxyethylated castor oil). TAXOL (paclitaxel) should not be used in patients with solid tumors who have baseline neutrophil counts of ...Read more
Precautions are...: The known cautions to taking Taxol (paclitaxel) include: - low blood counts - known hypersensitivity to castor oil - pre-existing liver problems - advanced age check with your doctor to see if any of your other medications interact with taxol (paclitaxel). ...Read moreSee 2 more doctor answers
Stops cell division.: In order to grow and spread, cancer cells need to divide and make copies of themselves. In order to divide and make copies of itself, the cell must prepare by organizing a kind of internal scaffolding, called microtubules. Taxol (paclitaxel) works by preventing the microtubules from functioning properly. Consequently, the cells can't divide properly and cancer growth is slowed. ...Read moreSee 1 more doctor answer