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Adriamycin Cytoxan Taxol And Fertility
Had an ultrasound that showed the liver to be slightly heterogeneous. Can that be due to past chemo therapy with Adriamycin, Cytoxan and Taxol?
Yes: Cytoxan can be damaging both to eggs and sperm and therefore needs to be monitored closely by your rheumatologist and fertility doctor. Cytoxan is also considered class d in pregnancy suggesting risk of fetal harm. Long term Prednisone therapy has little effect on sperm production or ovulation. ...Read more
Can you tell me about the long term side effects from the chemotherapy drugs adriamycin and cytoxin?
TWO MAJOR ONES: Adriamycin and Cytoxan is a great combination regimen used in breast cancer. The major long term side effects for both of these drugs is secondary leukemias, risk is around 1%. For adriamycin there is a concern for cardiotoxicity, but risk rises with cumulative dose. Risk is less than 10%. Patients get an echocardiogram or muga scan prior to therapy to evaluate heart status. Talk to your md. ...Read moreSee 1 more doctor answer
Rarely affects it.: Chemotherapy when given over a prescribed period of time such as in the neoadjuvant setting or post surgery rarely effects fertility. In the presence of metastatic disease where long term therapy is given then there is a chance of infertility. This can be true when doxorubicin and Ifex are employed for advanced metastatic sarcoma. ...Read more
Stops cell division.: In order to grow and spread, cancer cells need to divide and make copies of themselves. In order to divide and make copies of itself, the cell must prepare by organizing a kind of internal scaffolding, called microtubules. Taxol works by preventing the microtubules from functioning properly. Consequently, the cells can't divide properly and cancer growth is slowed. ...Read moreSee 1 more doctor answer
Stops cell division: Taxol is a chemotherapeutic agent that act to arrest rapidly dividing cells such as cancer cells. As such, it can also impede certain "normal" cell division such as white blood cels. Cell counts must be monitored frequently during treatment with this agent. ...Read moreSee 1 more doctor answer
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