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Doctor insights on: Adrenal Insufficiency Hyponatremia

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Is adrenal insufficiency hereditary?

Is adrenal insufficiency hereditary?

It can be.: One cause of adrenal insufficiency, addison's disease, is an auto-immune disorder. The immune system mistakenly makes antibodies targeting one or more proteins in the adrenal cortex, and winds up destroying the adrenal cortex, so that the adrenals can no longer make cortisol, or other hormones. As is true for most auto-immune disorders, a tendency to develop addison's can run in families. ...Read more

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Dr. David Geffner
261 doctors shared insights

Addison's Disease (Definition)

Chronic adrenal insufficiency. You may consult this site for more information on this topic. http://www.mayoclinic.org/diseases-conditions/addisons-disease/home/ovc-20155636 For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Drink enough water daily, so that your urine is mostly colorless. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any ...Read more


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What causes adrenal insufficiency?

What causes adrenal insufficiency?

Multiple causes: Infections of the gland by bacteria, including meningococcus and tb, metastatic tumors and primary tumors of adrenals, metabolic disorders, e.g., congenital adrenal hyperplasia, lack of pituitary stimulation, amyloid infiltration and sudden stoppage of steroid treatment etc. ...Read more

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What is primary adrenal insufficiency (addisons disease)?

What is primary adrenal insufficiency (addisons disease)?

Adrenal cortex: The adrenal cortex makes lots of hormones. Very important are cortisol and aldosterone which help maintain life and salt balance. Addison's disease is caused by adrenal cortex damage rendering it unable to make these hormones anymore, mostly autoimmune cause in us. Patients often have a bronzed look. Hydrocortisone replacement is a lifesaving necessity. Fludrocortisone may also become necessary. ...Read more

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Can cryofibrinogenemia cause partial adrenal insufficiency?

Can cryofibrinogenemia cause partial adrenal insufficiency?

Theoretically yes: Cryofibrinogenemia increases your risk of arterial and venous clots. Antiphospholipid syndrome does the same thing, and is associated in rare cases with primary adrenal insufficiency. So it's theoretically possible that the same mechanism could cause adrenal insufficiency in cryofibrinogenemia, by clotting off the blood vessels that supply the adrenal glands. Good question! ...Read more

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Can kidney cysts cause adrenal insufficiency?

Can kidney cysts cause adrenal insufficiency?

No: The adrenal glands, sitting on top of each kidney, are typically preserved in cystic kidney diseases. However that does not exclude screening for ai if clinical features are present such as unexplained hypotension, salt craving or worsening headaches. ...Read more

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How is adrenal insufficiency diagnosed?

How is adrenal insufficiency diagnosed?

Stimulation Test: Cortisol levels vary widely between individuals, and by time of day and are affected by illness. So random levels may not be helpful. A stimulation test with an injection of Cortrosyn to make the adrenals release cortisol is used. Blood is drawn just before, and 30 and 60 minutes after the Cortrosyn injection. Stimulated levels above 18-20 usually indicate normal adrenal function. ...Read more

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What is adrenal insufficiency?

What is adrenal insufficiency?

Low adrenal function: The adrenal glands make a number of different hormones, most importantly cortisol. When a person's adrenals cannot make normal amounts of cortisol, they are diagnosed with adrenal insufficiency, or failure. This can be due to a problem in the adrenals (infection, tumor, bleeding, auto-immune destruction) or in the pituitary or parts of the brain that control the adrenals. ...Read more

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What is acute adrenal insufficiency?

What is acute adrenal insufficiency?

Low cortisol : It generally means acute (recent) drop in adrenal gland hormonal production namely cortisol, a very important and life sustaining steroid. There are many reason why some one can develop ai. Autoimmune, infection, acute illness and trauma are a few examples. Need to discuss with an endocrinologist if there is need for hormonal replacement. ...Read more

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Can spironolactone cause low DHEA leading to adrenal insufficiency?

No: Spironolactone blocks some of the effects of "androgens" (including DHEA). It could potentially lower the levels of some of the androgens, but it will not lower cortisol and cause adrenal insufficiency. ...Read more

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Can Lyme disease cause adrenal insufficiency?

Lyme disease: There is much speculation, primarily in the lay press about "adrenal exhaustion" due to lyme disease. This seems to be purely theoretical and not based on any firm scientific evidence. The problem is that there is much we do not understand about lyme disease, and it has been the speculative cause of many unexplained illnesses. Stick to "proven" facts, and adrenal insufficiency is not. ...Read more

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Hypoadrenalism, hypocortisolism and adrenal insufficiency.. Is it the same?

Hypoadrenalism, hypocortisolism and adrenal insufficiency.. Is it the same?

Yes and no: They are often, and incorrectly, used interchangeably. Hypocortisolism is low cortisol, no matter what the cause. Hypoadrenalism is a general term which does not specify which hormone or hormones are low. Adrenal insufficiency means a deficiency in all adrenal hormones, but is incorrectly used to refer to low cortisol levels. Pituitary deficiency can cause low cortisolare you now properly confused. ...Read more

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Can adrenal insufficiency cause high blood pressure?

Can adrenal insufficiency cause high blood pressure?

Quite the opposite: Low cortisol level as its usually the case in ai, generally leads to low or low normal bp, not the contrary. If hypertension takes place in the presence of ai (and new in onset), then this may be an ominous sign as it may imply a cerebral (brain) insult either due to hypoglycemia or brain ischemia due to poor vascular perfusion. Please discuss this with your physician in a timely manner. ...Read more

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Will T3 (liothyronine) cure adrenal insufficiency?

Will T3 (liothyronine) cure adrenal insufficiency?

No: Adrenal insufficiency is the result of the failure of the adrenal glands to make cortisol. T3 (liothyronine) will not treat adrenal insufficiency because it is a thyroid hormone. ...Read more

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Do women with addison's adrenal insufficiency have low estrogen ?

Not significantly: The adrenal glands produce hormones which are precursors to estrogen, but that only comprises a small amount relative to what the ovaries make. Ovaries are the source of most estrogen in females. If menstrual cycles are irregular in properly treated addison's disease, autoimmune disease of the ovaries may need to be considered also. ...Read more

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Can adrenal insufficiency contribute to osteoporosis?

Over-treatment: In patients with adrenal insufficiency because of adrenal cortex dysfunction or central acth deficiency, over treating with steroids (ie: hydrocortisone, prednisone, dexamethasone) can certainly lead to osteoporosis. Patients with adrenal insufficiency are closely followed by their endocrinologists. ...Read more

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Why does thyroid replacement therapy in hypoadrenalism cause adrenal crisis?

Great question!: Even people with adrenal problems often make a little bit of cortisol. This little bit can be enough to keep them from getting very sick. In hypothyroidism the body's need for cortisol goes down and the little bit you make lasts longer. So if a person has both thyroid and adrenal disease, treating the thyroid without treating the adrenal problem first causes the little cortisol to run out quicker. ...Read more

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Does arterial insufficiency cause edema like chronic venous insufficiency?

Does arterial insufficiency cause edema like chronic venous insufficiency?

Venous edema: One of the hallmarks of chronic venous insufficiency is ankle and leg swelling. In the early stages of venous insufficiency, ankle and leg swelling occur at the end of the day and are relieved by leg elevation. In longstanding venous insufficiency, leg swelling is constant. Arterial insufficiency patients do not typically complain of lower extremity swellling. ...Read more

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Is adrenal insufficiency the same as addison's disease?

Not exactly: Addison' s disease is a state of adrenal insufficiency but not vice versa as there are many other causes besides ad ( an autoimmune disease) that can lead to cortisol deficiency state such as tuberculosis of the adrenals, hemorrhage of the adrenals, certain genetic storage syndromes and hypopituitarism. ...Read more

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Dr. Chad Levitt
4 doctors shared insights

Hyponatremia (Definition)

Normal sodium range from 135 to 145. Low sodium (hyponatremia) is less than 135. Some may have no symptoms at slight decrease in sodium level especially if the level dropped slowly. Rapid decrease or large drop in levels can cause confusion, seizures, coma and even death. Labs should always be rechecked to ...Read more


Addisonian Crisis (Definition)

Addisonian or acute adrenal crisis is a life-threatening condition that occurs when there is not enough cortisol, a hormone produced by the adrenal glands. It can manifest with fatigue, nausea, poor appetite, fever, joint pain, fatigue, coma, or seizure. Addison's disease is usually treated ...Read more