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Doctor insights on: Adrenal Insufficiency Acth

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Is adrenal insufficiency hereditary?

Is adrenal insufficiency hereditary?

It can be.: One cause of adrenal insufficiency, addison's disease, is an auto-immune disorder. The immune system mistakenly makes antibodies targeting one or more proteins in the adrenal cortex, and winds up destroying the adrenal cortex, so that the adrenals can no longer make cortisol, or other hormones. As is true for most auto-immune disorders, a tendency to develop addison's can run in families. ...Read more

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Dr. David Geffner
264 doctors shared insights

Addison's Disease (Definition)

Chronic adrenal insufficiency. You may consult this site for more information on this topic. http://www.mayoclinic.org/diseases-conditions/addisons-disease/home/ovc-20155636 For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Drink enough water daily, so that your urine is mostly colorless. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any ...Read more


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Acth level in cushings?

Acth level in cushings?

High in Cushing's: Elevated. Melanocortin secretion is also high and gives rise to frequent hyperpigmentation. ...Read more

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What is primary adrenal insufficiency (addisons disease)?

What is primary adrenal insufficiency (addisons disease)?

Adrenal cortex: The adrenal cortex makes lots of hormones. Very important are cortisol and aldosterone which help maintain life and salt balance. Addison's disease is caused by adrenal cortex damage rendering it unable to make these hormones anymore, mostly autoimmune cause in us. Patients often have a bronzed look. Hydrocortisone replacement is a lifesaving necessity. Fludrocortisone may also become necessary. ...Read more

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Adrenal fatigue, hypoadrenia, adrenal glands. Can i rebuild my adrenals?

Adrenal fatigue, hypoadrenia, adrenal glands. Can i rebuild my adrenals?

Yes: Should there be loss of adrenocortical function, steroid replacement is advocated to rebuild the normal stamina. ...Read more

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What is adrenal insufficiency?

What is adrenal insufficiency?

Low adrenal function: The adrenal glands make a number of different hormones, most importantly cortisol. When a person's adrenals cannot make normal amounts of cortisol, they are diagnosed with adrenal insufficiency, or failure. This can be due to a problem in the adrenals (infection, tumor, bleeding, auto-immune destruction) or in the pituitary or parts of the brain that control the adrenals. ...Read more

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What causes adrenal insufficiency?

What causes adrenal insufficiency?

Multiple causes: Infections of the gland by bacteria, including meningococcus and tb, metastatic tumors and primary tumors of adrenals, metabolic disorders, e.g., congenital adrenal hyperplasia, lack of pituitary stimulation, amyloid infiltration and sudden stoppage of steroid treatment etc. ...Read more

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Will T3 (liothyronine) cure adrenal insufficiency?

Will T3 (liothyronine) cure adrenal insufficiency?

No: Adrenal insufficiency is the result of the failure of the adrenal glands to make cortisol. T3 (liothyronine) will not treat adrenal insufficiency because it is a thyroid hormone. ...Read more

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How is adrenal insufficiency diagnosed?

How is adrenal insufficiency diagnosed?

Stimulation Test: Cortisol levels vary widely between individuals, and by time of day and are affected by illness. So random levels may not be helpful. A stimulation test with an injection of Cortrosyn to make the adrenals release cortisol is used. Blood is drawn just before, and 30 and 60 minutes after the Cortrosyn injection. Stimulated levels above 18-20 usually indicate normal adrenal function. ...Read more

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Hypoadrenalism, hypocortisolism and adrenal insufficiency.. Is it the same?

Hypoadrenalism, hypocortisolism and adrenal insufficiency.. Is it the same?

Yes and no: They are often, and incorrectly, used interchangeably. Hypocortisolism is low cortisol, no matter what the cause. Hypoadrenalism is a general term which does not specify which hormone or hormones are low. Adrenal insufficiency means a deficiency in all adrenal hormones, but is incorrectly used to refer to low cortisol levels. Pituitary deficiency can cause low cortisolare you now properly confused. ...Read more

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What is acth hormone deficiency?

Adrenal Insufficient: Acth is a pituitary hormone which stimulates the adrenal gland to secrete cortisol, a hormone necessary for life. When you no longer make acth you get adrenal insufficiency and have to take medication to replace the cortisol. Acth deficiency is often associated with other pituitary hormone deficiencies for which patients are screened. ...Read more

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Do women with addison's adrenal insufficiency have low estrogen ?

Not significantly: The adrenal glands produce hormones which are precursors to estrogen, but that only comprises a small amount relative to what the ovaries make. Ovaries are the source of most estrogen in females. If menstrual cycles are irregular in properly treated addison's disease, autoimmune disease of the ovaries may need to be considered also. ...Read more

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Can cryofibrinogenemia cause partial adrenal insufficiency?

Can cryofibrinogenemia cause partial adrenal insufficiency?

Theoretically yes: Cryofibrinogenemia increases your risk of arterial and venous clots. Antiphospholipid syndrome does the same thing, and is associated in rare cases with primary adrenal insufficiency. So it's theoretically possible that the same mechanism could cause adrenal insufficiency in cryofibrinogenemia, by clotting off the blood vessels that supply the adrenal glands. Good question! ...Read more

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Would acth and cortisol be low or high with adrenal insufficiency?

Would acth and cortisol be low or high with adrenal insufficiency?

Cortisol: Would be low. Acth would be high if it were an adrenal cause; low if it was a pituitary cause. ...Read more

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Could a pituitary tumor cause delayed cortisol response on acth stim test?

Could a pituitary tumor cause delayed cortisol response on acth stim test?

Definitely: If the tumor has destroyed the pituitary's ability to respond appropriately to hypothalamic cortisol releasing hormone, it can even lead to secondary adrenocortical insufficiency. Check w/your doctor. ...Read more

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Is central diabetes insipidus related to adrenal insuffiency? Im having an ACTH test to check adrenal function.

Is central diabetes insipidus related to adrenal insuffiency? Im having an ACTH test to check adrenal function.

Can be: Hi. If you have Addison's (skin, crease, gum, and scar darkening, malaise, nausea, dizziness, vital signs abnormalities, electrolyte abnormalities, etc), your ACTH will be very high. Addison's is most commonly an autoimmune disease. At least a subset of idiopathic central DI appears to be autoimmune in nature, and the risk of that goes up with other autoimmune diseases. If real, you got 2 rare 1's ...Read more

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What is acute adrenal insufficiency?

What is acute adrenal insufficiency?

Low cortisol : It generally means acute (recent) drop in adrenal gland hormonal production namely cortisol, a very important and life sustaining steroid. There are many reason why some one can develop ai. Autoimmune, infection, acute illness and trauma are a few examples. Need to discuss with an endocrinologist if there is need for hormonal replacement. ...Read more

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Does acth causes both aldosterone and cortisol secretion?

Does acth causes both aldosterone and cortisol secretion?

ACTH ALDO Cortisol: I have seen two families in which ACTH is the major driver for aldo production. They have the syndrome called GRA (Glucocorticoid Remedial Aldosteronism) caused by a cross over mutation in the genes controlling aldo production so that the major controller of aldo is ACTH. As you are young and making this question if you also have HTN your team should consider this. Many do not have low K. ...Read more

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Is adrenal insufficiency the same as addison's disease?

Not exactly: Addison' s disease is a state of adrenal insufficiency but not vice versa as there are many other causes besides ad ( an autoimmune disease) that can lead to cortisol deficiency state such as tuberculosis of the adrenals, hemorrhage of the adrenals, certain genetic storage syndromes and hypopituitarism. ...Read more

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Is primary adrenal insufficiency the same as addison's disease?

Often, yes: Addison's disease is an autoimmune disease which harms the cortex of the adrenal glands. However, anything that damages the adrenal cortex can also cause primary adrenal insufficiency. ...Read more

Dr. Oscar Novick
133 doctors shared insights

Addisonian Crisis (Definition)

Addisonian or acute adrenal crisis is a life-threatening condition that occurs when there is not enough cortisol, a hormone produced by the adrenal glands. It can manifest with fatigue, nausea, poor appetite, fever, joint pain, fatigue, coma, or seizure. Addison's disease is usually treated ...Read more


Dr. Walter Husar
148 doctors shared insights

Adrenocorticotropic Hormone (Definition)

It is one of several pituitary hormones - acth for short (the others control the thyroid gland, gonad glands, and others) that controls adrenal gland function in primarily making the hormone called cortisol (not to be confused with "adrenaline"), though the adrenal gland also ...Read more